[Term] id: PR:Q8BIJ6-1 name: isoleucine--tRNA ligase, mitochondrial isoform 1 (mouse) def: "An isoleucine--tRNA ligase, mitochondrial isoform 1 that is encoded in the genome of mouse." [PRO:DNx] comment: Category=organism-sequence. synonym: "mIARS2/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q8BIJ6-1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000043559 ! isoleucine--tRNA ligase, mitochondrial isoform 1 [Term] id: PR:Q8RXK8-2 name: isoleucine--tRNA ligase, chloroplastic/mitochondrial isoform 2 (Arabidopsis thaliana) def: "An isoleucine--tRNA ligase, chloroplastic/mitochondrial (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8RXK8-2." [PRO:DNx, UniProtKB:Q8RXK8] comment: Category=organism-sequence. synonym: "At-IARS2/iso:2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q8RXK8-2 is_a: PR:Q8RXK8 ! isoleucine--tRNA ligase, chloroplastic/mitochondrial (Arabidopsis thaliana) relationship: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana [Term] id: PR:000049905 name: isoleucine--tRNA ligase, mitochondrial acetylated 4 (mouse) def: "An isoleucine--tRNA ligase, mitochondrial (mouse) that has been acetylated on the residue at the position equivalent to Lys-725 of the amino acid sequence represented by UniProtKB:Q8BIJ6. UniProtKB:Q8BIJ6, Lys-725, MOD:00064." [PMID:23576753, PRO:HJD] comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:23576753). Note: Large-scale experiment. synonym: "mIARS2/Ac:4" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q8BIJ6, Lys-725, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q8BIJ6 ! isoleucine--tRNA ligase, mitochondrial (mouse) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:Q8BIJ6 name: isoleucine--tRNA ligase, mitochondrial (mouse) def: "An isoleucine--tRNA ligase, mitochondrial that is encoded in the genome of mouse." [OMA:Q8BIJ6, PRO:DNx] comment: Category=organism-gene. synonym: "Iars2" RELATED Gene-based [UniProtKB:Q8BIJ6] synonym: "mIARS2" EXACT PRO-short-label [PRO:DNx] synonym: "IleRS (mouse)" BROAD [PRO:DAN, UniProtKB:Q8BIJ6] synonym: "isoleucine--tRNA ligase (mouse)" BROAD [PRO:DAN] synonym: "isoleucyl-tRNA synthetase (mouse)" BROAD [PRO:DAN, UniProtKB:Q8BIJ6] synonym: "isoleucyl-tRNA synthetase, mitochondrial (mouse)" EXACT [PRO:DAN] xref: UniProtKB:Q8BIJ6 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000008877 ! isoleucine--tRNA ligase, mitochondrial relationship: has_gene_template MGI:1919586 ! Iars2 (mouse) [Term] id: PR:000043559 name: isoleucine--tRNA ligase, mitochondrial isoform 1 def: "An isoleucine--tRNA ligase, mitochondrial that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NSE4-1 or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=sequence. synonym: "IARS2/iso:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000008877 ! isoleucine--tRNA ligase, mitochondrial [Term] id: PR:Q8RXK8-1 name: isoleucine--tRNA ligase, chloroplastic/mitochondrial isoform 1 (Arabidopsis thaliana) def: "An isoleucine--tRNA ligase, chloroplastic/mitochondrial (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8RXK8-1." [PRO:DNx, UniProtKB:Q8RXK8] comment: Category=organism-sequence. synonym: "At-IARS2/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q8RXK8-1 is_a: PR:Q8RXK8 ! isoleucine--tRNA ligase, chloroplastic/mitochondrial (Arabidopsis thaliana) relationship: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana [Term] id: PR:000049906 name: isoleucine--tRNA ligase, mitochondrial acetylated 5 (mouse) def: "An isoleucine--tRNA ligase, mitochondrial (mouse) that has been acetylated on the residue at the position equivalent to Lys-775 of the amino acid sequence represented by UniProtKB:Q8BIJ6. UniProtKB:Q8BIJ6, Lys-775, MOD:00064." [PMID:23576753, PRO:HJD] comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:23576753). synonym: "mIARS2/Ac:5" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q8BIJ6, Lys-775, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q8BIJ6 ! isoleucine--tRNA ligase, mitochondrial (mouse) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:000049907 name: isoleucine--tRNA ligase, mitochondrial acetylated 6 (mouse) def: "An isoleucine--tRNA ligase, mitochondrial (mouse) that has been acetylated on the residue at the position equivalent to Lys-803 of the amino acid sequence represented by UniProtKB:Q8BIJ6. UniProtKB:Q8BIJ6, Lys-803, MOD:00064." [PMID:23576753, PRO:HJD] comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:23576753). Note: Large-scale experiment. synonym: "mIARS2/Ac:6" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q8BIJ6, Lys-803, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q8BIJ6 ! isoleucine--tRNA ligase, mitochondrial (mouse) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:000049904 name: isoleucine--tRNA ligase, mitochondrial acetylated 3 (mouse) def: "An isoleucine--tRNA ligase, mitochondrial (mouse) that has been acetylated on the residue at the position equivalent to Lys-540 of the amino acid sequence represented by UniProtKB:Q8BIJ6. UniProtKB:Q8BIJ6, Lys-540, MOD:00064." [PMID:23576753, PRO:HJD] comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:23576753). Note: Large-scale experiment. synonym: "mIARS2/Ac:3" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q8BIJ6, Lys-540, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q8BIJ6 ! isoleucine--tRNA ligase, mitochondrial (mouse) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:000047932 name: isoleucine--tRNA ligase, mitochondrial, transit peptide removed form (human) def: "An isoleucine--tRNA ligase, mitochondrial (human) that has had the transit peptide removed. UniProtKB:Q9NSE4, 49-1012." [PRO:DNx, Reactome:R-HSA-379571] comment: Category=organism-modification. synonym: "PRO_0000233335" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hIARS2/TransPep-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q9NSE4, 49-1012" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-379571 "PR:000047932 located_in GO:0005759" intersection_of: PR:Q9NSE4 ! isoleucine--tRNA ligase, mitochondrial (human) intersection_of: lacks_part SO:0000725 ! transit_peptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000049902 name: isoleucine--tRNA ligase, mitochondrial acetylated 1 (mouse) def: "An isoleucine--tRNA ligase, mitochondrial (mouse) that has been acetylated on the residue at the position equivalent to Lys-74 of the amino acid sequence represented by UniProtKB:Q8BIJ6. UniProtKB:Q8BIJ6, Lys-74, MOD:00064." [PMID:23576753, PRO:HJD] comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:23576753). Note: Large-scale experiment. synonym: "mIARS2/Ac:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q8BIJ6, Lys-74, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q8BIJ6 ! isoleucine--tRNA ligase, mitochondrial (mouse) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:000049903 name: isoleucine--tRNA ligase, mitochondrial acetylated 2 (mouse) def: "An isoleucine--tRNA ligase, mitochondrial (mouse) that has been acetylated on the residue at the position equivalent to Lys-500 of the amino acid sequence represented by UniProtKB:Q8BIJ6. UniProtKB:Q8BIJ6, Lys-500, MOD:00064." [PMID:23576753, PRO:HJD] comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:23576753). Note: Large-scale experiment. synonym: "mIARS2/Ac:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q8BIJ6, Lys-500, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q8BIJ6 ! isoleucine--tRNA ligase, mitochondrial (mouse) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:Q9NSE4 name: isoleucine--tRNA ligase, mitochondrial (human) def: "An isoleucine--tRNA ligase, mitochondrial that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9NSE4] comment: Category=organism-gene. synonym: "IARS2" RELATED Gene-based [UniProtKB:Q9NSE4] synonym: "hIARS2" EXACT PRO-short-label [PRO:DNx] synonym: "IleRS (human)" BROAD [PRO:DAN] synonym: "isoleucine--tRNA ligase (human)" BROAD [PRO:DAN] synonym: "isoleucyl-tRNA synthetase (human)" BROAD [PRO:DAN] xref: UniProtKB:Q9NSE4 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000008877 ! isoleucine--tRNA ligase, mitochondrial relationship: has_gene_template HGNC:29685 ! IARS2 (human) [Term] id: PR:Q9USL3 name: isoleucine--tRNA ligase, mitochondrial (Schizosaccharomyces pombe 972h-) def: "An isoleucine--tRNA ligase, mitochondrial that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:Q9USL3, PRO:DNx] comment: Category=organism-gene. synonym: "ism1" RELATED Gene-based [UniProtKB:Q9USL3] synonym: "SPCC18B5.08c" RELATED Gene-based [UniProtKB:Q9USL3] synonym: "Spom972h-IARS2" EXACT PRO-short-label [PRO:DNx] synonym: "IleRS (Schizosaccharomyces pombe 972h-)" BROAD [PRO:DAN, UniProtKB:Q9USL3] synonym: "isoleucine--tRNA ligase (Schizosaccharomyces pombe 972h-)" BROAD [PRO:DAN] synonym: "isoleucyl-tRNA synthetase (Schizosaccharomyces pombe 972h-)" BROAD [PRO:DAN, UniProtKB:Q9USL3] synonym: "isoleucyl-tRNA synthetase, mitochondrial (Schizosaccharomyces pombe 972h-)" EXACT [PRO:DAN] xref: UniProtKB:Q9USL3 intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h- intersection_of: PR:000008877 ! isoleucine--tRNA ligase, mitochondrial relationship: has_gene_template PomBase:SPCC18B5.08c ! ism1 (Schizosaccharomyces pombe) [Term] id: PR:P48526 name: isoleucine--tRNA ligase, mitochondrial (yeast) def: "An isoleucine--tRNA ligase, mitochondrial that is encoded in the genome of yeast." [OMA:P48526, PRO:DNx] comment: Category=organism-gene. synonym: "ISM1" RELATED Gene-based [UniProtKB:P48526] synonym: "yIARS2" EXACT PRO-short-label [PRO:DNx] synonym: "YPL040C" RELATED Gene-based [UniProtKB:P48526] synonym: "P7102.10" RELATED Gene-based [UniProtKB:P48526] synonym: "IleRS (yeast)" BROAD [PRO:DAN, UniProtKB:P48526] synonym: "isoleucine--tRNA ligase (yeast)" BROAD [PRO:DAN] synonym: "isoleucyl-tRNA synthetase (yeast)" BROAD [PRO:DAN, UniProtKB:P48526] synonym: "isoleucyl-tRNA synthetase, mitochondrial (yeast)" EXACT [PRO:DAN] xref: UniProtKB:P48526 intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C intersection_of: PR:000008877 ! isoleucine--tRNA ligase, mitochondrial relationship: has_gene_template SGD:S000005961 ! ISM1 (yeast) [Term] id: PR:Q9NSE4-1 name: isoleucine--tRNA ligase, mitochondrial isoform 1 (human) def: "An isoleucine--tRNA ligase, mitochondrial isoform 1 that is encoded in the genome of human." [PRO:DNx] comment: Category=organism-sequence. synonym: "hIARS2/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9NSE4-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000043559 ! isoleucine--tRNA ligase, mitochondrial isoform 1 [Term] id: PR:Q54CE4 name: probable isoleucine--tRNA ligase, mitochondrial (Dictyostelium discoideum) def: "An isoleucine--tRNA ligase, mitochondrial that is encoded in the genome of Dictyostelium discoideum." [OMA:Q54CE4, PRO:DNx] comment: Category=organism-gene. synonym: "mileS" RELATED Gene-based [UniProtKB:Q54CE4] synonym: "Dicty-IARS2" EXACT PRO-short-label [PRO:DNx] synonym: "DDB_G0293030" RELATED Gene-based [UniProtKB:Q54CE4] synonym: "IleRS (Dictyostelium discoideum)" BROAD [PRO:DAN, UniProtKB:Q54CE4] synonym: "isoleucine--tRNA ligase (Dictyostelium discoideum)" BROAD [PRO:DAN] synonym: "isoleucyl-tRNA synthetase (Dictyostelium discoideum)" BROAD [PRO:DAN, UniProtKB:Q54CE4] synonym: "isoleucyl-tRNA synthetase, mitochondrial (Dictyostelium discoideum)" EXACT [PRO:DAN] xref: UniProtKB:Q54CE4 intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum intersection_of: PR:000008877 ! isoleucine--tRNA ligase, mitochondrial relationship: has_gene_template dictyBase:DDB_G0293030 ! mileS (Dictyostelium discoideum) [Term] id: PR:000008877 name: isoleucine--tRNA ligase, mitochondrial def: "A protein that is a translation product of the human IARS2 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "IARS2" EXACT PRO-short-label [PRO:DNx] synonym: "IleRS" BROAD [PRO:DAN] synonym: "isoleucine--tRNA ligase" BROAD [PRO:DAN] synonym: "isoleucyl-tRNA synthetase" BROAD [PRO:DAN] synonym: "isoleucyl-tRNA synthetase, mitochondrial" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:Q8RXK8 name: isoleucine--tRNA ligase, chloroplastic/mitochondrial (Arabidopsis thaliana) def: "An isoleucine--tRNA ligase, mitochondrial that is encoded in the genome of Arabidopsis thaliana." [OMA:Q8RXK8, PRO:DNx] comment: Category=organism-gene. synonym: "OVA2" RELATED Gene-based [UniProtKB:Q8RXK8] synonym: "At-IARS2" EXACT PRO-short-label [PRO:DNx] synonym: "At5g49030" RELATED Gene-based [UniProtKB:Q8RXK8] synonym: "K19E20.18" RELATED Gene-based [UniProtKB:Q8RXK8] synonym: "IleRS (Arabidopsis thaliana)" BROAD [PRO:DAN, UniProtKB:Q8RXK8] synonym: "isoleucine--tRNA ligase (Arabidopsis thaliana)" BROAD [PRO:DAN] synonym: "protein OVULE ABORTION 2 (Arabidopsis thaliana)" EXACT [UniProtKB:Q8RXK8] synonym: "isoleucyl-tRNA synthetase (Arabidopsis thaliana)" BROAD [PRO:DAN, UniProtKB:Q8RXK8] synonym: "isoleucyl-tRNA synthetase, chloroplastic/mitochondrial (Arabidopsis thaliana)" EXACT [PRO:DAN] xref: UniProtKB:Q8RXK8 intersection_of: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana intersection_of: PR:000008877 ! isoleucine--tRNA ligase, mitochondrial relationship: has_gene_template Araport:AT5G49030 ! OVA2 (Arabidopsis thaliana)