[Term]
id: PR:000045622
name: serine/threonine-protein kinase LATS1 phosphorylated 1 (human)
def: "A serine/threonine-protein kinase LATS1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-464 of the amino acid sequence represented by UniProtKB:O95835-1. Example: UniProtKB:O95835-1, Ser-464, MOD:00046." [PMID:19927127, iPTMnet:O95835]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:19927127). Status=unreviewed.
synonym: "hLATS1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O95835-1, Ser-464, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:O95835 ! serine/threonine-protein kinase LATS1 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O95835-2
name: serine/threonine-protein kinase LATS1 isoform h2 (human)
def: "A serine/threonine-protein kinase LATS1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O95835-2." [PRO:DNx, UniProtKB:O95835]
comment: Category=organism-sequence.
synonym: "hLATS1/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O95835-2
is_a: PR:O95835 ! serine/threonine-protein kinase LATS1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O95835-1
name: serine/threonine-protein kinase LATS1 isoform h1 (human)
def: "A serine/threonine-protein kinase LATS1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O95835-1." [PRO:DNx, UniProtKB:O95835]
comment: Category=organism-sequence.
synonym: "hLATS1/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O95835-1
is_a: PR:O95835 ! serine/threonine-protein kinase LATS1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000009686
name: serine/threonine-protein kinase LATS1
def: "A protein that is a translation product of the human LATS1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "LATS1" EXACT PRO-short-label [PRO:DNx]
synonym: "WARTS" RELATED Gene-based []
synonym: "WARTS protein kinase" EXACT []
synonym: "large tumor suppressor homolog 1" EXACT []
xref: IUPHARobj:1515
is_a: PR:000000001 ! protein

[Term]
id: PR:O95835
name: serine/threonine-protein kinase LATS1 (human)
def: "A serine/threonine-protein kinase LATS1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:O95835]
comment: Category=organism-gene.
synonym: "LATS1" RELATED Gene-based [UniProtKB:O95835]
synonym: "WARTS" RELATED Gene-based [UniProtKB:O95835]
synonym: "hLATS1" EXACT PRO-short-label [PRO:DNx]
synonym: "h-warts" EXACT [UniProtKB:O95835]
synonym: "WARTS protein kinase (human)" EXACT [UniProtKB:O95835]
synonym: "large tumor suppressor homolog 1 (human)" EXACT [UniProtKB:O95835]
xref: Reactome:R-HSA-2028562 "PR:O95835 located_in GO:0005829"
xref: DTO:03100264
xref: UniProtKB:O95835
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000009686 ! serine/threonine-protein kinase LATS1
relationship: has_gene_template HGNC:6514 ! LATS1 (human)

[Term]
id: PR:Q8BYR2
name: serine/threonine-protein kinase LATS1 (mouse)
def: "A serine/threonine-protein kinase LATS1 that is encoded in the genome of mouse." [OMA:Q8BYR2, PRO:DNx]
comment: Category=organism-gene.
synonym: "Lats1" RELATED Gene-based [UniProtKB:Q8BYR2]
synonym: "Warts" RELATED Gene-based [UniProtKB:Q8BYR2]
synonym: "mLATS1" EXACT PRO-short-label [PRO:DNx]
synonym: "WARTS protein kinase (mouse)" EXACT [UniProtKB:Q8BYR2]
synonym: "large tumor suppressor homolog 1 (mouse)" EXACT [UniProtKB:Q8BYR2]
xref: UniProtKB:Q8BYR2
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000009686 ! serine/threonine-protein kinase LATS1
relationship: has_gene_template MGI:1333883 ! Lats1 (mouse)