[Term]
id: PR:Q9Y6D9-3
name: mitotic spindle assembly checkpoint protein MAD1 isoform h2 (human)
def: "A mitotic spindle assembly checkpoint protein MAD1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y6D9-3." [PRO:DNx, UniProtKB:Q9Y6D9]
comment: Category=organism-sequence.
synonym: "hMAD1L1/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9Y6D9-3
is_a: PR:Q9Y6D9 ! mitotic spindle assembly checkpoint protein MAD1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9Y6D9-1
name: mitotic spindle assembly checkpoint protein MAD1 isoform h1 (human)
def: "A mitotic spindle assembly checkpoint protein MAD1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y6D9-1." [PRO:DNx, UniProtKB:Q9Y6D9]
comment: Category=organism-sequence.
synonym: "hMAD1L1/iso:h1" EXACT PRO-short-label [PRO:DNx]
synonym: "mitotic spindle assembly checkpoint protein MAD1 isoform MAD1-alpha (human)" EXACT [UniProtKB:Q9Y6D9]
xref: UniProtKB:Q9Y6D9-1
is_a: PR:Q9Y6D9 ! mitotic spindle assembly checkpoint protein MAD1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000035562
name: mitotic spindle assembly checkpoint protein MAD1 phosphorylated 1 (human)
def: "A mitotic spindle assembly checkpoint protein MAD1 phosphorylated 1 in human." [PMID:10198256, PRO:KER]
comment: Category=organism-modification. Kinase=("BUB1"; PR:O43683).
synonym: "hMAD1L1/Phos:1" EXACT PRO-short-label [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000035561 ! mitotic spindle assembly checkpoint protein MAD1 phosphorylated 1
relationship: has_part MOD:00696 ! phosphorylated residue

[Term]
id: PR:000010037
name: mitotic spindle assembly checkpoint protein MAD1
def: "A protein that is a translation product of the human MAD1L1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "MAD1" RELATED Gene-based []
synonym: "MAD1L1" EXACT PRO-short-label [PRO:DNx]
synonym: "TXBP181" RELATED Gene-based []
synonym: "MAD1-like protein 1" EXACT []
synonym: "Tax-binding protein 181" EXACT []
synonym: "mitotic checkpoint MAD1 protein homolog" EXACT []
synonym: "mitotic arrest deficient 1-like protein 1" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000046109
name: mitotic spindle assembly checkpoint protein MAD1 phosphorylated 2 (human)
def: "A mitotic spindle assembly checkpoint protein MAD1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-214 of the amino acid sequence represented by UniProtKB:Q9Y6D9-1. Example: UniProtKB:Q9Y6D9-1, Ser-214, MOD:00046." [PMID:24728176, iPTMnet:Q9Y6D9]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:24728176). Status=unreviewed.
synonym: "hMAD1L1/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9Y6D9-1, Ser-214, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q9Y6D9 ! mitotic spindle assembly checkpoint protein MAD1 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9Y6D9
name: mitotic spindle assembly checkpoint protein MAD1 (human)
def: "A mitotic spindle assembly checkpoint protein MAD1 that is encoded in the genome of human." [PMID:10198256, PMID:12837246, PRO:KER]
comment: Category=organism-gene.
synonym: "MAD1" RELATED Gene-based [UniProtKB:Q9Y6D9]
synonym: "hMAD1" BROAD [PRO:DNx]
synonym: "HsMAD1" EXACT [UniProtKB:Q9Y6D9]
synonym: "MAD1L1" RELATED Gene-based [UniProtKB:Q9Y6D9]
synonym: "TXBP181" RELATED Gene-based [UniProtKB:Q9Y6D9]
synonym: "hMAD1L1" EXACT PRO-short-label [PRO:DNx]
synonym: "MAD1-like protein 1 (human)" EXACT [UniProtKB:Q9Y6D9]
synonym: "Tax-binding protein 181 (human)" EXACT [UniProtKB:Q9Y6D9]
synonym: "mitotic checkpoint MAD1 protein homolog (human)" EXACT [UniProtKB:Q9Y6D9]
synonym: "mitotic arrest deficient 1-like protein 1 (human)" EXACT [UniProtKB:Q9Y6D9]
xref: Reactome:R-HSA-141433 "PR:Q9Y6D9 located_in GO:0005829"
xref: UniProtKB:Q9Y6D9
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000010037 ! mitotic spindle assembly checkpoint protein MAD1
relationship: has_gene_template HGNC:6762 ! MAD1L1 (human)