[Term]
id: PR:P53779
name: mitogen-activated protein kinase 10 (human)
def: "A mitogen-activated protein kinase 10 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P53779]
comment: Category=organism-gene.
synonym: "JNK3" RELATED Gene-based [UniProtKB:P53779]
synonym: "JNK3A" RELATED Gene-based [UniProtKB:P53779]
synonym: "MAPK10" RELATED Gene-based [UniProtKB:P53779]
synonym: "PRKM10" RELATED Gene-based [UniProtKB:P53779]
synonym: "SAPK1B" RELATED Gene-based [UniProtKB:P53779]
synonym: "hMAPK10" EXACT PRO-short-label [PRO:DNx]
synonym: "MAPK 10 (human)" EXACT [UniProtKB:P53779]
synonym: "MAP kinase 10 (human)" EXACT [UniProtKB:P53779]
synonym: "MAP kinase p49 3F12 (human)" EXACT [UniProtKB:P53779]
synonym: "c-Jun N-terminal kinase 3 (human)" EXACT [UniProtKB:P53779]
synonym: "stress-activated protein kinase 1b (human)" EXACT [UniProtKB:P53779]
synonym: "stress-activated protein kinase JNK3 (human)" EXACT [UniProtKB:P53779]
xref: Reactome:R-HSA-450352 "PR:P53779 located_in GO:0005829"
xref: DTO:03100322
xref: UniProtKB:P53779
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000010151 ! mitogen-activated protein kinase 10
relationship: has_gene_template HGNC:6872 ! MAPK10 (human)

[Term]
id: PR:P53779-3
name: mitogen-activated protein kinase 10 isoform h3 (human)
def: "A mitogen-activated protein kinase 10 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P53779-3." [PRO:DNx, UniProtKB:P53779]
comment: Category=organism-sequence.
synonym: "hMAPK10/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P53779-3
is_a: PR:P53779 ! mitogen-activated protein kinase 10 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P53779-2
name: mitogen-activated protein kinase 10 isoform hAlpha-1 (human)
def: "A mitogen-activated protein kinase 10 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P53779-2." [PRO:DNx, UniProtKB:P53779]
comment: Category=organism-sequence.
synonym: "hMAPK10/iso:hAlpha-1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P53779-2
is_a: PR:P53779 ! mitogen-activated protein kinase 10 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P53779-1
name: mitogen-activated protein kinase 10 isoform hAlpha-2 (human)
def: "A mitogen-activated protein kinase 10 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P53779-1." [PRO:DNx, UniProtKB:P53779]
comment: Category=organism-sequence.
synonym: "hMAPK10/iso:hAlpha-2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P53779-1
is_a: PR:P53779 ! mitogen-activated protein kinase 10 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000010151
name: mitogen-activated protein kinase 10
def: "A protein that is a translation product of the human MAPK10 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "JNK3" RELATED Gene-based []
synonym: "JNK3A" RELATED Gene-based []
synonym: "Serk2" RELATED Gene-based []
synonym: "MAPK10" EXACT PRO-short-label [PRO:DNx]
synonym: "PRKM10" RELATED Gene-based []
synonym: "SAPK1B" RELATED Gene-based []
synonym: "MAPK 10" EXACT []
synonym: "MAP kinase 10" EXACT []
synonym: "MAP kinase p49 3F12" EXACT []
synonym: "c-Jun N-terminal kinase 3" EXACT []
synonym: "stress-activated protein kinase JNK3" EXACT []
xref: IUPHARobj:1498
is_a: PR:000000001 ! protein

[Term]
id: PR:000048315
name: mitogen-activated protein kinase 10 phosphorylated 1 (human)
def: "A mitogen-activated protein kinase 10 (human) that has been phosphorylated on the residue at the position equivalent to Thr-221, and phosphotyrosine at position 223 of the amino acid sequence represented by UniProtKB:P53779. UniProtKB:P53779, Thr-221, MOD:00047|Tyr-223, MOD:00048." [PRO:DNx, Reactome:R-HSA-450214, Reactome:R-HSA-450311]
comment: Category=organism-modification.
synonym: "hMAPK10/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P53779, Thr-221, MOD:00047|Tyr-223, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-450214 "PR:000048315 located_in GO:0005829"
xref: Reactome:R-HSA-450311 "PR:000048315 located_in GO:0005654"
is_a: PR:P53779 ! mitogen-activated protein kinase 10 (human)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens