[Term]
id: PR:000048325
name: mitogen-activated protein kinase 6 phosphorylated 2 (human)
def: "A mitogen-activated protein kinase 6 (human) that has been post-translationally modified to include phosphoserine at positions 684, 688 and 705, and phosphothreonine at position 698 of the amino acid sequence represented by UniProtKB:Q16659. UniProtKB:Q16659, Ser-684/Ser-688/Ser-705, MOD:00046|Thr-698, MOD:00047." [PRO:DNx, Reactome:R-HSA-5692665]
comment: Category=organism-modification.
synonym: "hMAPK6/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q16659, Ser-684/Ser-688/Ser-705, MOD:00046|Thr-698, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5692665 "PR:000048325 located_in GO:0005654"
is_a: PR:Q16659 ! mitogen-activated protein kinase 6 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000048324
name: mitogen-activated protein kinase 6 phosphorylated 1 (human)
def: "A mitogen-activated protein kinase 6 (human) that has been phosphorylated on the residue at the position equivalent to Ser-189 of the amino acid sequence represented by UniProtKB:Q16659. UniProtKB:Q16659, Ser-189, MOD:00046." [PRO:DNx, Reactome:R-HSA-5687015, Reactome:R-HSA-5687019]
comment: Category=organism-modification.
synonym: "hMAPK6/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q16659, Ser-189, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5687015 "PR:000048324 located_in GO:0005654"
xref: Reactome:R-HSA-5687019 "PR:000048324 located_in GO:0005829"
is_a: PR:Q16659 ! mitogen-activated protein kinase 6 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q16659
name: mitogen-activated protein kinase 6 (human)
def: "A mitogen-activated protein kinase 6 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q16659]
comment: Category=organism-gene.
synonym: "ERK3" RELATED Gene-based [UniProtKB:Q16659]
synonym: "MAPK6" RELATED Gene-based [UniProtKB:Q16659]
synonym: "PRKM6" RELATED Gene-based [UniProtKB:Q16659]
synonym: "hMAPK6" EXACT PRO-short-label [PRO:DNx]
synonym: "ERK-3 (human)" EXACT [UniProtKB:Q16659]
synonym: "MAPK 6 (human)" EXACT [UniProtKB:Q16659]
synonym: "p97-MAPK (human)" EXACT [UniProtKB:Q16659]
synonym: "MAP kinase 6 (human)" EXACT [UniProtKB:Q16659]
synonym: "MAP kinase isoform p97 (human)" EXACT [UniProtKB:Q16659]
synonym: "extracellular signal-regulated kinase 3 (human)" EXACT [UniProtKB:Q16659]
xref: Reactome:R-HSA-5686979 "PR:Q16659 located_in GO:0005829"
xref: Reactome:R-HSA-5692686 "PR:Q16659 located_in GO:0005654"
xref: DTO:03100318
xref: UniProtKB:Q16659
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000010158 ! mitogen-activated protein kinase 6
relationship: has_gene_template HGNC:6879 ! MAPK6 (human)

[Term]
id: PR:000010158
name: mitogen-activated protein kinase 6
def: "A protein that is a translation product of the human MAPK6 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "ERK3" RELATED Gene-based []
synonym: "ERK-3" EXACT []
synonym: "MAPK6" EXACT PRO-short-label [PRO:DNx]
synonym: "PRKM6" RELATED Gene-based []
synonym: "Prkm4" RELATED Gene-based []
synonym: "MAPK 6" EXACT []
synonym: "p97-MAPK" EXACT []
synonym: "MAP kinase 6" EXACT []
synonym: "MAP kinase isoform p97" EXACT []
synonym: "extracellular signal-regulated kinase 3" EXACT []
xref: IUPHARobj:2092
is_a: PR:000000001 ! protein