[Term] id: PR:000048368 name: myocyte-specific enhancer factor 2C phosphorylated 2 (human) def: "A myocyte-specific enhancer factor 2C (human) that has been post-translationally modified to include phosphothreonine at positions 293 and 300, and phosphoserine at position 419 of the amino acid sequence represented by UniProtKB:Q06413. UniProtKB:Q06413, Thr-293/Thr-300, MOD:00047|Ser-419, MOD:00046." [PMID:9069290, PRO:DAN] comment: Category=organism-modification. Note: The modified site indicated here (Ser-419) is referred to as Ser-387 in some manuscripts. [PRO:DAN, PMID:9069290] synonym: "hMEF2C/Phos:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q06413, Thr-293/Thr-300, MOD:00047|Ser-419, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q06413 ! myocyte-specific enhancer factor 2C (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: has_part MOD:00047 ! O-phospho-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q06413-1 name: myocyte-specific enhancer factor 2C isoform 1 (human) def: "A myocyte-specific enhancer factor 2C isoform 1 that is encoded in the genome of human." [PRO:CNA] comment: Category=organism-sequence. synonym: "hMEF2C/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q06413-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000027925 ! myocyte-specific enhancer factor 2C isoform 1 [Term] id: PR:Q06413-5 name: myocyte-specific enhancer factor 2C isoform h5 (human) def: "A myocyte-specific enhancer factor 2C (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q06413-5." [PRO:DNx, UniProtKB:Q06413] comment: Category=organism-sequence. synonym: "hMEF2C/iso:h5" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q06413-5 is_a: PR:Q06413 ! myocyte-specific enhancer factor 2C (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q06413-3 name: myocyte-specific enhancer factor 2C isoform h3 (human) def: "A myocyte-specific enhancer factor 2C (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q06413-3." [PRO:DNx, UniProtKB:Q06413] comment: Category=organism-sequence. synonym: "hMEF2C/iso:h3" EXACT PRO-short-label [PRO:DNx] synonym: "myocyte-specific enhancer factor 2C isoform Brain (human)" EXACT [UniProtKB:Q06413] synonym: "myocyte-specific enhancer factor 2C isoform hMEF2C-delta32 (human)" EXACT [UniProtKB:Q06413] xref: UniProtKB:Q06413-3 is_a: PR:Q06413 ! myocyte-specific enhancer factor 2C (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q06413-2 name: myocyte-specific enhancer factor 2C isoform 2 (human) def: "A myocyte-specific enhancer factor 2C isoform 2 that is encoded in the genome of human." [PRO:CNA] comment: Category=organism-sequence. synonym: "hMEF2C/iso:2" EXACT PRO-short-label [PRO:DNx] synonym: "myocyte-specific enhancer factor 2C isoform Muscle (human)" EXACT [UniProtKB:Q06413] xref: UniProtKB:Q06413-2 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000027927 ! myocyte-specific enhancer factor 2C isoform 2 [Term] id: PR:000010311 name: myocyte-specific enhancer factor 2C def: "A protein that is a translation product of the human MEF2C gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "MEF2C" EXACT PRO-short-label [PRO:DNx] synonym: "myocyte enhancer factor 2C" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:Q06413-4 name: myocyte-specific enhancer factor 2C isoform h4 (human) def: "A myocyte-specific enhancer factor 2C (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q06413-4." [PRO:DNx, UniProtKB:Q06413] comment: Category=organism-sequence. synonym: "hMEF2C/iso:h4" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q06413-4 is_a: PR:Q06413 ! myocyte-specific enhancer factor 2C (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000048367 name: myocyte-specific enhancer factor 2C phosphorylated 1 (human) def: "A myocyte-specific enhancer factor 2C (human) that has been phosphorylated on the residue at the position equivalent to Ser-396 of the amino acid sequence represented by UniProtKB:Q06413. UniProtKB:Q06413, Ser-396, MOD:00046." [PRO:DNx, Reactome:R-HSA-199942] comment: Category=organism-modification. synonym: "hMEF2C/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q06413, Ser-396, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-199942 "PR:000048367 located_in GO:0005654" is_a: PR:Q06413 ! myocyte-specific enhancer factor 2C (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q06413-6 name: myocyte-specific enhancer factor 2C isoform h6 (human) def: "A myocyte-specific enhancer factor 2C (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q06413-6." [PRO:DNx, UniProtKB:Q06413] comment: Category=organism-sequence. synonym: "hMEF2C/iso:h6" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q06413-6 is_a: PR:Q06413 ! myocyte-specific enhancer factor 2C (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q06413 name: myocyte-specific enhancer factor 2C (human) def: "A myocyte-specific enhancer factor 2C that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q06413] comment: Category=organism-gene. synonym: "MEF2C" RELATED Gene-based [UniProtKB:Q06413] synonym: "hMEF2C" EXACT PRO-short-label [PRO:DNx] synonym: "myocyte enhancer factor 2C (human)" EXACT [UniProtKB:Q06413] xref: Reactome:R-HSA-199938 "PR:Q06413 located_in GO:0005654" xref: UniProtKB:Q06413 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000010311 ! myocyte-specific enhancer factor 2C relationship: has_gene_template HGNC:6996 ! MEF2C (human)