[Term] id: PR:P08581-1 name: hepatocyte growth factor receptor isoform 1 (human) def: "A hepatocyte growth factor receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08581-1." [PRO:DNx, UniProtKB:P08581] comment: Category=organism-sequence. Requested by=PubChem. synonym: "hMET/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P08581-1 is_a: PR:P08581 ! hepatocyte growth factor receptor (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P08581-2 name: hepatocyte growth factor receptor isoform h2 (human) def: "A hepatocyte growth factor receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08581-2." [PRO:DNx, UniProtKB:P08581] comment: Category=organism-sequence. synonym: "hMET/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P08581-2 is_a: PR:P08581 ! hepatocyte growth factor receptor (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P08581-3 name: hepatocyte growth factor receptor isoform h3 (human) def: "A hepatocyte growth factor receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08581-3." [PRO:DNx, UniProtKB:P08581] comment: Category=organism-sequence. synonym: "hMET/iso:h3" EXACT PRO-short-label [PRO:DNx] synonym: "hepatocyte growth factor receptor isoform Soluble MET variant 4 (human)" EXACT [UniProtKB:P08581] xref: UniProtKB:P08581-3 is_a: PR:P08581 ! hepatocyte growth factor receptor (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000045657 name: hepatocyte growth factor receptor phosphorylated 1 (human) def: "A hepatocyte growth factor receptor (human) that has been phosphorylated on the residue at the position equivalent to Ser-985 of the amino acid sequence represented by UniProtKB:P08581-1. Example: UniProtKB:P08581-1, Ser-985, MOD:00046." [PMID:15075332, iPTMnet:P08581] comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:15075332). Status=unreviewed. synonym: "hMET/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P08581-1, Ser-985, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P08581 ! hepatocyte growth factor receptor (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000010335 name: hepatocyte growth factor receptor def: "An HGF/MSP receptor type tyrosine-protein kinase that is a translation product of the human MET gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "MET" EXACT PRO-short-label [PRO:DNx] synonym: "SF receptor" EXACT [] synonym: "HGF receptor" EXACT [] synonym: "HGF/SF receptor" EXACT [] synonym: "proto-oncogene c-Met" EXACT [] synonym: "scatter factor receptor" EXACT [] synonym: "tyrosine-protein kinase Met" EXACT [] xref: IUPHARobj:1815 is_a: PR:000001816 ! HGF/MSP receptor type tyrosine-protein kinase [Term] id: PR:000048370 name: hepatocyte growth factor receptor, signal peptide removed form (human) def: "A hepatocyte growth factor receptor (human) that has had the signal peptide removed. UniProtKB:P08581, 25-1390." [PRO:DNx, Reactome:R-HSA-419603] comment: Category=organism-modification. synonym: "hMET/SigPep-" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000024440" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:P08581, 25-1390" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-419603 "PR:000048370 located_in GO:0005886" intersection_of: PR:P08581 ! hepatocyte growth factor receptor (human) intersection_of: lacks_part SO:0000418 ! signal_peptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P08581 name: hepatocyte growth factor receptor (human) def: "A hepatocyte growth factor receptor that is encoded in the genome of human." [PRO:DNx, UniProtKB:P08581] comment: Category=organism-gene. synonym: "MET" RELATED Gene-based [UniProtKB:P08581] synonym: "hMET" EXACT PRO-short-label [PRO:DNx] synonym: "SF receptor (human)" EXACT [UniProtKB:P08581] synonym: "HGF receptor (human)" EXACT [UniProtKB:P08581] synonym: "HGF/SF receptor (human)" EXACT [UniProtKB:P08581] synonym: "proto-oncogene c-Met (human)" EXACT [UniProtKB:P08581] synonym: "scatter factor receptor (human)" EXACT [UniProtKB:P08581] synonym: "tyrosine-protein kinase Met (human)" EXACT [UniProtKB:P08581] xref: DTO:03100313 xref: UniProtKB:P08581 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000010335 ! hepatocyte growth factor receptor relationship: has_gene_template HGNC:7029 ! MET (human)