[Term]
id: PR:000010369
name: mitofusin-1
def: "A protein that is a translation product of the human MFN1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "MFN1" EXACT PRO-short-label [PRO:DNx]
synonym: "Fzo homolog" EXACT []
synonym: "transmembrane GTPase MFN1" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000048376
name: mitofusin-1 ubiquitinated form (human)
def: "A mitofusin-1 (human) that includes at least one ubiquitinated lysine. UniProtKB:Q8IWA4, MOD:01148." [PRO:DNx, Reactome:R-HSA-5205679]
comment: Category=organism-modification.
synonym: "hMFN1/UbiqLys+" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q8IWA4, MOD:01148" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5205679 "PR:000048376 located_in GO:0005741"
intersection_of: has_part MOD:01148 ! ubiquitinylated lysine
intersection_of: PR:Q8IWA4 ! mitofusin-1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q8IWA4-1
name: mitofusin-1 isoform h1 (human)
def: "A mitofusin-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IWA4-1." [PRO:DNx, UniProtKB:Q8IWA4]
comment: Category=organism-sequence.
synonym: "hMFN1/iso:h1" EXACT PRO-short-label [PRO:DNx]
synonym: "mitofusin-1 isoform TG741 (human)" EXACT [UniProtKB:Q8IWA4]
xref: UniProtKB:Q8IWA4-1
is_a: PR:Q8IWA4 ! mitofusin-1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q8IWA4-2
name: mitofusin-1 isoform h2 (human)
def: "A mitofusin-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IWA4-2." [PRO:DNx, UniProtKB:Q8IWA4]
comment: Category=organism-sequence.
synonym: "hMFN1/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "mitofusin-1 isoform TG370 (human)" EXACT [UniProtKB:Q8IWA4]
xref: UniProtKB:Q8IWA4-2
is_a: PR:Q8IWA4 ! mitofusin-1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q8IWA4-3
name: mitofusin-1 isoform h3 (human)
def: "A mitofusin-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IWA4-3." [PRO:DNx, UniProtKB:Q8IWA4]
comment: Category=organism-sequence.
synonym: "hMFN1/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8IWA4-3
is_a: PR:Q8IWA4 ! mitofusin-1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q8IWA4
name: mitofusin-1 (human)
def: "A mitofusin-1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q8IWA4]
comment: Category=organism-gene.
synonym: "MFN1" RELATED Gene-based [UniProtKB:Q8IWA4]
synonym: "hMFN1" EXACT PRO-short-label [PRO:DNx]
synonym: "Fzo homolog (human)" EXACT [UniProtKB:Q8IWA4]
synonym: "transmembrane GTPase MFN1 (human)" EXACT [UniProtKB:Q8IWA4]
xref: Reactome:R-HSA-992745 "PR:Q8IWA4 located_in GO:0005741"
xref: UniProtKB:Q8IWA4
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000010369 ! mitofusin-1
relationship: has_gene_template HGNC:18262 ! MFN1 (human)