[Term]
id: PR:000011115
name: E3 ubiquitin-protein ligase NEDD4
def: "A HECT domain-containing E3 ubiquitin-protein ligase with WW domains that is a translation product of the human NEDD4 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "RPF1" RELATED Gene-based []
synonym: "NEDD4" EXACT PRO-short-label [PRO:DNx]
synonym: "PIG53" RELATED Gene-based []
synonym: "NEDD-4" EXACT []
synonym: "Nedd4a" RELATED Gene-based []
synonym: "NEDD4-1" RELATED Gene-based []
synonym: "KIAA0093" RELATED Gene-based []
synonym: "HECT-type E3 ubiquitin transferase NEDD4" EXACT []
synonym: "cell proliferation-inducing gene 53 protein" EXACT []
synonym: "neural precursor cell expressed developmentally down-regulated protein 4" EXACT []
is_a: PR:000000016 ! HECT domain-containing E3 ubiquitin-protein ligase with WW domains

[Term]
id: PR:P46934-2
name: E3 ubiquitin-protein ligase NEDD4 isoform h2 (human)
def: "An E3 ubiquitin-protein ligase NEDD4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P46934-2." [PRO:DNx, UniProtKB:P46934]
comment: Category=organism-sequence.
synonym: "hNEDD4/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P46934-2
is_a: PR:P46934 ! E3 ubiquitin-protein ligase NEDD4 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P46934-3
name: E3 ubiquitin-protein ligase NEDD4 isoform h3 (human)
def: "An E3 ubiquitin-protein ligase NEDD4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P46934-3." [PRO:DNx, UniProtKB:P46934]
comment: Category=organism-sequence.
synonym: "hNEDD4/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P46934-3
is_a: PR:P46934 ! E3 ubiquitin-protein ligase NEDD4 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P46934
name: E3 ubiquitin-protein ligase NEDD4 (human)
def: "An E3 ubiquitin-protein ligase NEDD4 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P46934]
comment: Category=organism-gene.
synonym: "RPF1" RELATED Gene-based [UniProtKB:P46934]
synonym: "NEDD4" RELATED Gene-based [UniProtKB:P46934]
synonym: "PIG53" RELATED Gene-based [UniProtKB:P46934]
synonym: "hNEDD4" EXACT PRO-short-label [PRO:DNx]
synonym: "NEDD4-1" RELATED Gene-based [UniProtKB:P46934]
synonym: "KIAA0093" RELATED Gene-based [UniProtKB:P46934]
synonym: "NEDD-4 (human)" EXACT [UniProtKB:P46934]
synonym: "HECT-type E3 ubiquitin transferase NEDD4 (human)" EXACT [UniProtKB:P46934]
synonym: "cell proliferation-inducing gene 53 protein (human)" EXACT [UniProtKB:P46934]
synonym: "neural precursor cell expressed developmentally down-regulated protein 4 (human)" EXACT [UniProtKB:P46934]
xref: Reactome:R-HSA-975992 "PR:P46934 located_in GO:0005829"
xref: UniProtKB:P46934
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000011115 ! E3 ubiquitin-protein ligase NEDD4
relationship: has_gene_template HGNC:7727 ! NEDD4 (human)

[Term]
id: PR:P46934-1
name: E3 ubiquitin-protein ligase NEDD4 isoform h1 (human)
def: "An E3 ubiquitin-protein ligase NEDD4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P46934-1." [PRO:DNx, UniProtKB:P46934]
comment: Category=organism-sequence.
synonym: "hNEDD4/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P46934-1
is_a: PR:P46934 ! E3 ubiquitin-protein ligase NEDD4 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P46934-4
name: E3 ubiquitin-protein ligase NEDD4 isoform h4 (human)
def: "An E3 ubiquitin-protein ligase NEDD4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P46934-4." [PRO:DNx, UniProtKB:P46934]
comment: Category=organism-sequence.
synonym: "hNEDD4/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P46934-4
is_a: PR:P46934 ! E3 ubiquitin-protein ligase NEDD4 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens