[Term]
id: PR:000036290
name: NAD(P)H dehydrogenase [quinone] 1 isoform 1 acetylated 1 (human)
def: "An NAD(P)H dehydrogenase [quinone] 1 isoform 1 (human) that is N-terminal Met acetylated. UniProtKB:P15559-1, Met-1, MOD:00058." [PRO:DAN, TDR:2431]
comment: Category=organism-modification. Note: Top down proteomics. Evidence=(ECO:0000006).
synonym: "hNQO1/iso:1/Ac:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P15559-1, Met-1, MOD:00058" EXACT PRO-proteoform-std [PRO:DNx]
xref: TDR:2431
is_a: PR:P15559-1 ! NAD(P)H dehydrogenase [quinone] 1 isoform 1 (human)
relationship: has_part MOD:00058 ! N-acetyl-L-methionine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000048632
name: NAD(P)H dehydrogenase [quinone] 1, initiator methionine removed form (human)
def: "An NAD(P)H dehydrogenase [quinone] 1 (human) that has had the initiator methionine removed. UniProtKB:P15559, 2-274." [PRO:DNx, Reactome:R-HSA-350610]
comment: Category=organism-modification.
synonym: "PRO_0000071622" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hNQO1/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P15559, 2-274" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-350610 "PR:000048632 located_in GO:0005829"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:P15559 ! NAD(P)H dehydrogenase [quinone] 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P15559
name: NAD(P)H dehydrogenase [quinone] 1 (human)
def: "An NAD(P)H dehydrogenase [quinone] 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P15559]
comment: Category=organism-gene.
synonym: "DIA4" RELATED Gene-based [UniProtKB:P15559]
synonym: "NQO1" RELATED Gene-based [UniProtKB:P15559]
synonym: "NMOR1" RELATED Gene-based [UniProtKB:P15559]
synonym: "hNQO1" EXACT PRO-short-label [PRO:DNx]
synonym: "DTD (human)" BROAD [UniProtKB:P15559]
synonym: "QR1 (human)" EXACT [UniProtKB:P15559]
synonym: "azoreductase (human)" EXACT [UniProtKB:P15559]
synonym: "DT-diaphorase (human)" EXACT [UniProtKB:P15559]
synonym: "menadione reductase (human)" EXACT [UniProtKB:P15559]
synonym: "quinone reductase 1 (human)" EXACT [UniProtKB:P15559]
synonym: "phylloquinone reductase (human)" EXACT [UniProtKB:P15559]
synonym: "NAD(P)H:quinone oxidoreductase 1 (human)" EXACT [UniProtKB:P15559]
xref: UniProtKB:P15559
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000011388 ! NAD(P)H dehydrogenase [quinone] 1
relationship: has_gene_template HGNC:2874 ! NQO1 (human)

[Term]
id: PR:P15559-3
name: NAD(P)H dehydrogenase [quinone] 1 isoform h3 (human)
def: "An NAD(P)H dehydrogenase [quinone] 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P15559-3." [PRO:DNx, UniProtKB:P15559]
comment: Category=organism-sequence.
synonym: "hNQO1/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P15559-3
is_a: PR:P15559 ! NAD(P)H dehydrogenase [quinone] 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P15559-2
name: NAD(P)H dehydrogenase [quinone] 1 isoform h2 (human)
def: "An NAD(P)H dehydrogenase [quinone] 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P15559-2." [PRO:DNx, UniProtKB:P15559]
comment: Category=organism-sequence.
synonym: "hNQO1/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P15559-2
is_a: PR:P15559 ! NAD(P)H dehydrogenase [quinone] 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P15559-1
name: NAD(P)H dehydrogenase [quinone] 1 isoform 1 (human)
def: "An NAD(P)H dehydrogenase [quinone] 1 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hNQO1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P15559-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000038934 ! NAD(P)H dehydrogenase [quinone] 1 isoform 1

[Term]
id: PR:000011388
name: NAD(P)H dehydrogenase [quinone] 1
def: "A protein that is a translation product of the human NQO1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "DTD" EXACT []
synonym: "QR1" EXACT []
synonym: "DIA4" RELATED Gene-based []
synonym: "NQO1" EXACT PRO-short-label [PRO:DNx]
synonym: "Nmo1" RELATED Gene-based []
synonym: "NMOR1" RELATED Gene-based []
synonym: "azoreductase" EXACT []
synonym: "DT-diaphorase" EXACT []
synonym: "menadione reductase" EXACT []
synonym: "quinone reductase 1" EXACT []
synonym: "phylloquinone reductase" EXACT []
synonym: "NAD(P)H:quinone oxidoreductase 1" EXACT []
is_a: PR:000000001 ! protein