[Term] id: PR:Q8CIN4 name: serine/threonine-protein kinase PAK 2 (mouse) def: "A serine/threonine-protein kinase PAK 2 that is encoded in the genome of mouse." [OMA:Q8CIN4, PRO:DNx] comment: Category=organism-gene. synonym: "Pak2" RELATED Gene-based [UniProtKB:Q8CIN4] synonym: "mPAK2" EXACT PRO-short-label [PRO:DNx] synonym: "PAK-2 (mouse)" EXACT [UniProtKB:Q8CIN4] synonym: "gamma-PAK (mouse)" EXACT [UniProtKB:Q8CIN4] synonym: "p21-activated kinase 2 (mouse)" EXACT [UniProtKB:Q8CIN4] xref: UniProtKB:Q8CIN4 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000012241 ! serine/threonine-protein kinase PAK 2 relationship: has_gene_template MGI:1339984 ! Pak2 (mouse) [Term] id: PR:Q13177-1 name: serine/threonine-protein kinase PAK 2 isoform 1 (human) def: "A serine/threonine-protein kinase PAK 2 isoform 1 that is encoded in the genome of human." [PRO:DNx] comment: Category=organism-sequence. synonym: "hPAK2/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q13177-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000040397 ! serine/threonine-protein kinase PAK 2 isoform 1 [Term] id: PR:Q8CIN4-1 name: serine/threonine-protein kinase PAK 2 isoform 1 (mouse) def: "A serine/threonine-protein kinase PAK 2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx] comment: Category=organism-sequence. synonym: "mPAK2/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q8CIN4-1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000040397 ! serine/threonine-protein kinase PAK 2 isoform 1 [Term] id: PR:Q64303-1 name: serine/threonine-protein kinase PAK 2 isoform 1 (rat) def: "A serine/threonine-protein kinase PAK 2 isoform 1 that is encoded in the genome of rat." [PRO:DNx] comment: Category=organism-sequence. synonym: "rPAK2/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q64303-1 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000040397 ! serine/threonine-protein kinase PAK 2 isoform 1 [Term] id: PR:Q13177 name: serine/threonine-protein kinase PAK 2 (human) def: "A serine/threonine-protein kinase PAK 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q13177] comment: Category=organism-gene. Requested by=PubChem. synonym: "PAK2" RELATED Gene-based [UniProtKB:Q13177] synonym: "hPAK2" EXACT PRO-short-label [PRO:DNx] synonym: "p58 (human)" BROAD [UniProtKB:Q13177] synonym: "PAK-2 (human)" EXACT [UniProtKB:Q13177] synonym: "PAK65 (human)" EXACT [UniProtKB:Q13177] synonym: "gamma-PAK (human)" EXACT [UniProtKB:Q13177] synonym: "S6/H4 kinase (human)" EXACT [UniProtKB:Q13177] synonym: "p21-activated kinase 2 (human)" EXACT [UniProtKB:Q13177] xref: Reactome:R-HSA-164946 "PR:Q13177 located_in GO:0005886" xref: DTO:03100385 xref: UniProtKB:Q13177 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000012241 ! serine/threonine-protein kinase PAK 2 relationship: has_gene_template HGNC:8591 ! PAK2 (human) [Term] id: PR:000040397 name: serine/threonine-protein kinase PAK 2 isoform 1 def: "A serine/threonine-protein kinase PAK 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13177-1 or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=sequence. synonym: "PAK2/iso:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000012241 ! serine/threonine-protein kinase PAK 2 [Term] id: PR:000012241 name: serine/threonine-protein kinase PAK 2 def: "A protein that is a translation product of the human PAK2 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "p58" BROAD [PRO:DNx] synonym: "PAK2" EXACT PRO-short-label [PRO:DNx] synonym: "PAK-2" EXACT [] synonym: "PAK65" EXACT [] synonym: "gamma-PAK" EXACT [] synonym: "S6/H4 kinase" EXACT [] synonym: "p21-activated kinase 2" EXACT [] xref: IUPHARobj:2134 is_a: PR:000000001 ! protein [Term] id: PR:Q1PFH8 name: calcium-dependent protein kinase 19 (Arabidopsis thaliana) def: "A serine/threonine-protein kinase PAK 2 that is encoded in the genome of Arabidopsis thaliana." [OMA:Q1PFH8, PRO:DNx] comment: Category=organism-gene. synonym: "CPK19" RELATED Gene-based [UniProtKB:Q1PFH8] synonym: "At-PAK2" EXACT PRO-short-label [PRO:DNx] synonym: "F8K4.14" RELATED Gene-based [UniProtKB:Q1PFH8] synonym: "At1g61950" RELATED Gene-based [UniProtKB:Q1PFH8] xref: UniProtKB:Q1PFH8 intersection_of: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana intersection_of: PR:000012241 ! serine/threonine-protein kinase PAK 2 relationship: has_gene_template Araport:AT1G61950 ! CPK19 (Arabidopsis thaliana) [Term] id: PR:000048689 name: serine/threonine-protein kinase PAK 2, initiator methionine removed form (human) def: "A serine/threonine-protein kinase PAK 2 (human) that has had the initiator methionine removed. UniProtKB:Q13177, 2-524." [PRO:DNx, Reactome:R-HSA-211604] comment: Category=organism-modification. synonym: "PRO_0000086465" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hPAK2/InitMet-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q13177, 2-524" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-211604 "PR:000048689 located_in GO:0005829" intersection_of: lacks_part PR:000021937 ! initiator methionine intersection_of: PR:Q13177 ! serine/threonine-protein kinase PAK 2 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000048691 name: serine/threonine-protein kinase PAK 2 phosphorylated 3 (human) def: "A serine/threonine-protein kinase PAK 2 (human) that has been phosphorylated on the residue at the position equivalent to Ser-141, and phosphothreonine at position 402 of the amino acid sequence represented by UniProtKB:Q13177. UniProtKB:Q13177, Ser-141, MOD:00046|Thr-402, MOD:00047." [PRO:DNx, Reactome:R-HSA-399824, Reactome:R-HSA-5096524] comment: Category=organism-modification. synonym: "hPAK2/Phos:3" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q13177, Ser-141, MOD:00046|Thr-402, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-399824 "PR:000048691 located_in GO:0005829" xref: Reactome:R-HSA-5096524 "PR:000048691 located_in GO:0005886" is_a: PR:Q13177 ! serine/threonine-protein kinase PAK 2 (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: has_part MOD:00047 ! O-phospho-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000048690 name: serine/threonine-protein kinase PAK 2, initiator methionine removed phosphorylated 2 (human) def: "A serine/threonine-protein kinase PAK 2 (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphoserine at positions 19, 20, 55, 192 and 197 of the amino acid sequence represented by UniProtKB:Q13177. UniProtKB:Q13177, 2-524, Ser-19/Ser-20/Ser-55/Ser-192/Ser-197, MOD:00046." [PRO:DNx, Reactome:R-HSA-211609] comment: Category=organism-modification. synonym: "hPAK2/InitMet-/Phos:2" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000086465, Ser-19/Ser-20/Ser-55/Ser-192/Ser-197, MOD:00046" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q13177, 2-524, Ser-19/Ser-20/Ser-55/Ser-192/Ser-197, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-211609 "PR:000048690 located_in GO:0005829" is_a: PR:Q13177 ! serine/threonine-protein kinase PAK 2 (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000048692 name: serine/threonine-protein kinase PAK 2 phosphorylated 4 (human) def: "A serine/threonine-protein kinase PAK 2 (human) that has been phosphorylated on the residue at the position equivalent to Tyr-130, phosphoserine at position 141, and phosphothreonine at position 402 of the amino acid sequence represented by UniProtKB:Q13177. UniProtKB:Q13177, Tyr-130, MOD:00048|Ser-141, MOD:00046|Thr-402, MOD:00047." [PRO:DNx, Reactome:R-HSA-5218705] comment: Category=organism-modification. synonym: "hPAK2/Phos:4" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q13177, Tyr-130, MOD:00048|Ser-141, MOD:00046|Thr-402, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-5218705 "PR:000048692 located_in GO:0005829" is_a: PR:Q13177 ! serine/threonine-protein kinase PAK 2 (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: has_part MOD:00047 ! O-phospho-L-threonine relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000045902 name: serine/threonine-protein kinase PAK 2 phosphorylated 1 (human) def: "A serine/threonine-protein kinase PAK 2 (human) that has been phosphorylated at Tyr-130. UniProtKB:Q13177, Tyr-130, MOD:00048." [PMID:12215529, iPTMnet:Q13177] comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:12215529). Status=unreviewed. synonym: "hPAK2/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q13177, Tyr-130, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q13177 ! serine/threonine-protein kinase PAK 2 (human) relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q64303 name: serine/threonine-protein kinase PAK 2 (rat) def: "A serine/threonine-protein kinase PAK 2 that is encoded in the genome of rat." [OMA:Q64303, PRO:DNx] comment: Category=organism-gene. synonym: "Pak2" RELATED Gene-based [UniProtKB:Q64303] synonym: "rPAK2" EXACT PRO-short-label [PRO:DNx] synonym: "PAK-2 (rat)" RELATED [UniProtKB:Q64303] synonym: "gamma-PAK (rat)" EXACT [UniProtKB:Q64303] synonym: "p21-activated kinase 2 (rat)" EXACT [UniProtKB:Q64303] xref: UniProtKB:Q64303 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000012241 ! serine/threonine-protein kinase PAK 2 relationship: has_gene_template RGD:61953 ! Pak2 (rat) [Term] id: PR:000020865 name: serine/threonine-protein kinase PAK 2 proteolytic cleavage product def: "A serine/threonine-protein kinase PAK 2 that has been processed by proteolytic cleavage." [PRO:DNx] comment: Category=modification. synonym: "PAK2/ClvPrd" EXACT PRO-short-label [PRO:DNx] intersection_of: output_of GO:0016485 ! protein processing intersection_of: PR:000012241 ! serine/threonine-protein kinase PAK 2