[Term]
id: PR:O75914
name: serine/threonine-protein kinase PAK 3 (human)
def: "A serine/threonine-protein kinase PAK 3 that is encoded in the genome of human." [PRO:DNx, UniProtKB:O75914]
comment: Category=organism-gene.
synonym: "PAK3" RELATED Gene-based [UniProtKB:O75914]
synonym: "OPHN3" RELATED Gene-based [UniProtKB:O75914]
synonym: "hPAK3" EXACT PRO-short-label [PRO:DNx]
synonym: "PAK-3 (human)" EXACT [UniProtKB:O75914]
synonym: "beta-PAK (human)" EXACT [UniProtKB:O75914]
synonym: "oligophrenin-3 (human)" EXACT [UniProtKB:O75914]
synonym: "p21-activated kinase 3 (human)" EXACT [UniProtKB:O75914]
xref: Reactome:R-HSA-428457 "PR:O75914 located_in GO:0005829"
xref: DTO:03100386
xref: UniProtKB:O75914
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000012242 ! serine/threonine-protein kinase PAK 3
relationship: has_gene_template HGNC:8592 ! PAK3 (human)

[Term]
id: PR:000012242
name: serine/threonine-protein kinase PAK 3
def: "A protein that is a translation product of the human PAK3 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "PAK3" EXACT PRO-short-label [PRO:DNx]
synonym: "Pakb" RELATED Gene-based []
synonym: "Stk4" RELATED Gene-based []
synonym: "OPHN3" RELATED Gene-based []
synonym: "PAK-3" EXACT []
synonym: "beta-PAK" EXACT []
synonym: "oligophrenin-3" EXACT []
synonym: "p21-activated kinase 3" EXACT []
synonym: "CDC42/RAC effector kinase PAK-B" EXACT []
xref: IUPHARobj:2135
is_a: PR:000000001 ! protein

[Term]
id: PR:000048693
name: serine/threonine-protein kinase PAK 3 phosphorylated 1 (human)
def: "A serine/threonine-protein kinase PAK 3 (human) that has been phosphorylated on the residue at the position equivalent to Ser-154, and phosphothreonine at position 436 of the amino acid sequence represented by UniProtKB:O75914. UniProtKB:O75914, Ser-154, MOD:00046|Thr-436, MOD:00047." [PRO:DNx, Reactome:R-HSA-3928479, Reactome:R-HSA-5357471]
comment: Category=organism-modification.
synonym: "hPAK3/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O75914, Ser-154, MOD:00046|Thr-436, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-3928479 "PR:000048693 located_in GO:0005886"
xref: Reactome:R-HSA-5357471 "PR:000048693 located_in GO:0005829"
is_a: PR:O75914 ! serine/threonine-protein kinase PAK 3 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O75914-4
name: serine/threonine-protein kinase PAK 3 isoform h4 (human)
def: "A serine/threonine-protein kinase PAK 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75914-4." [PRO:DNx, UniProtKB:O75914]
comment: Category=organism-sequence.
synonym: "hPAK3/iso:h4" EXACT PRO-short-label [PRO:DNx]
synonym: "serine/threonine-protein kinase PAK 3 isoform PAK3c (human)" EXACT [UniProtKB:O75914]
xref: UniProtKB:O75914-4
is_a: PR:O75914 ! serine/threonine-protein kinase PAK 3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O75914-3
name: serine/threonine-protein kinase PAK 3 isoform h3 (human)
def: "A serine/threonine-protein kinase PAK 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75914-3." [PRO:DNx, UniProtKB:O75914]
comment: Category=organism-sequence.
synonym: "hPAK3/iso:h3" EXACT PRO-short-label [PRO:DNx]
synonym: "serine/threonine-protein kinase PAK 3 isoform PAK3cb (human)" EXACT [UniProtKB:O75914]
xref: UniProtKB:O75914-3
is_a: PR:O75914 ! serine/threonine-protein kinase PAK 3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O75914-2
name: serine/threonine-protein kinase PAK 3 isoform 2 (human)
def: "A serine/threonine-protein kinase PAK 3 isoform 2 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hPAK3/iso:2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O75914-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000038407 ! serine/threonine-protein kinase PAK 3 isoform 2

[Term]
id: PR:O75914-1
name: serine/threonine-protein kinase PAK 3 isoform 1 (human)
def: "A serine/threonine-protein kinase PAK 3 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hPAK3/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "serine/threonine-protein kinase PAK 3 isoform PAK3b (human)" EXACT [UniProtKB:O75914]
xref: UniProtKB:O75914-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000038406 ! serine/threonine-protein kinase PAK 3 isoform 1