[Term] id: PR:O60260-7 name: E3 ubiquitin-protein ligase parkin isoform h7 (human) def: "An E3 ubiquitin-protein ligase parkin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O60260-7." [PRO:DNx, UniProtKB:O60260] comment: Category=organism-sequence. synonym: "hPRKN/iso:h7" EXACT PRO-short-label [PRO:DNx] synonym: "E3 ubiquitin-protein ligase parkin isoform SV5,9DEL (human)" EXACT [UniProtKB:O60260] xref: UniProtKB:O60260-7 is_a: PR:O60260 ! E3 ubiquitin-protein ligase parkin (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:O60260-6 name: E3 ubiquitin-protein ligase parkin isoform h6 (human) def: "An E3 ubiquitin-protein ligase parkin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O60260-6." [PRO:DNx, UniProtKB:O60260] comment: Category=organism-sequence. synonym: "hPRKN/iso:h6" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:O60260-6 is_a: PR:O60260 ! E3 ubiquitin-protein ligase parkin (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:O60260-5 name: E3 ubiquitin-protein ligase parkin isoform h5 (human) def: "An E3 ubiquitin-protein ligase parkin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O60260-5." [PRO:DNx, UniProtKB:O60260] comment: Category=organism-sequence. synonym: "hPRKN/iso:h5" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:O60260-5 is_a: PR:O60260 ! E3 ubiquitin-protein ligase parkin (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:O60260-4 name: E3 ubiquitin-protein ligase parkin isoform h4 (human) def: "An E3 ubiquitin-protein ligase parkin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O60260-4." [PRO:DNx, UniProtKB:O60260] comment: Category=organism-sequence. synonym: "hPRKN/iso:h4" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:O60260-4 is_a: PR:O60260 ! E3 ubiquitin-protein ligase parkin (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:O60260-3 name: E3 ubiquitin-protein ligase parkin isoform h3 (human) def: "An E3 ubiquitin-protein ligase parkin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O60260-3." [PRO:DNx, UniProtKB:O60260] comment: Category=organism-sequence. synonym: "hPRKN/iso:h3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:O60260-3 is_a: PR:O60260 ! E3 ubiquitin-protein ligase parkin (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:O60260-2 name: E3 ubiquitin-protein ligase parkin isoform 2 (human) def: "An E3 ubiquitin-protein ligase parkin isoform 2 that is encoded in the genome of human." [PRO:DNx] comment: Category=organism-sequence. synonym: "hPRKN/iso:2" EXACT PRO-short-label [PRO:DNx] synonym: "E3 ubiquitin-protein ligase parkin isoform SV5DEL (human)" EXACT [UniProtKB:O60260] xref: UniProtKB:O60260-2 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000038231 ! E3 ubiquitin-protein ligase parkin isoform 2 [Term] id: PR:O60260-1 name: E3 ubiquitin-protein ligase parkin isoform 1 (human) def: "An E3 ubiquitin-protein ligase parkin isoform 1 that is encoded in the genome of human." [PRO:DNx] comment: Category=organism-sequence. synonym: "hPRKN/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:O60260-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000038230 ! E3 ubiquitin-protein ligase parkin isoform 1 [Term] id: PR:Q9WVS6 name: E3 ubiquitin-protein ligase parkin (mouse) def: "An E3 ubiquitin-protein ligase parkin that is encoded in the genome of mouse." [OMA:Q9WVS6, PRO:DNx] comment: Category=organism-gene. synonym: "Prkn" RELATED Gene-based [UniProtKB:Q9WVS6] synonym: "Park2" RELATED Gene-based [UniProtKB:Q9WVS6] synonym: "mPRKN" EXACT PRO-short-label [PRO:DNx] synonym: "parkin RBR E3 ubiquitin-protein ligase (mouse)" EXACT [UniProtKB:Q9WVS6] xref: UniProtKB:Q9WVS6 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000012285 ! E3 ubiquitin-protein ligase parkin relationship: has_gene_template MGI:1355296 ! Prkn (mouse) [Term] id: PR:Q9JK66-5 name: E3 ubiquitin-protein ligase parkin isoform 5 (rat) def: "An E3 ubiquitin-protein ligase parkin isoform 2 that is encoded in the genome of rat." [PRO:DNx] comment: Category=organism-sequence. synonym: "rPRKN/iso:5" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9JK66-5 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000038231 ! E3 ubiquitin-protein ligase parkin isoform 2 [Term] id: PR:Q9WVS6-2 name: E3 ubiquitin-protein ligase parkin isoform m2 (mouse) def: "An E3 ubiquitin-protein ligase parkin (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9WVS6-2." [PRO:DNx, UniProtKB:Q9WVS6] comment: Category=organism-sequence. synonym: "mPRKN/iso:m2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9WVS6-2 is_a: PR:Q9WVS6 ! E3 ubiquitin-protein ligase parkin (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:Q9WVS6-3 name: E3 ubiquitin-protein ligase parkin isoform m3 (mouse) def: "An E3 ubiquitin-protein ligase parkin (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9WVS6-3." [PRO:DNx, UniProtKB:Q9WVS6] comment: Category=organism-sequence. synonym: "mPRKN/iso:m3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9WVS6-3 is_a: PR:Q9WVS6 ! E3 ubiquitin-protein ligase parkin (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:Q9JK66-1 name: E3 ubiquitin-protein ligase parkin isoform 1 (rat) def: "An E3 ubiquitin-protein ligase parkin isoform 1 that is encoded in the genome of rat." [PRO:DNx] comment: Category=organism-sequence. synonym: "rPRKN/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9JK66-1 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000038230 ! E3 ubiquitin-protein ligase parkin isoform 1 [Term] id: PR:O60260-8 name: E3 ubiquitin-protein ligase parkin isoform h8 (human) def: "An E3 ubiquitin-protein ligase parkin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O60260-8." [PRO:DNx, UniProtKB:O60260] comment: Category=organism-sequence. synonym: "hPRKN/iso:h8" EXACT PRO-short-label [PRO:DNx] synonym: "E3 ubiquitin-protein ligase parkin isoform SV9DEL (human)" EXACT [UniProtKB:O60260] xref: UniProtKB:O60260-8 is_a: PR:O60260 ! E3 ubiquitin-protein ligase parkin (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000048694 name: E3 ubiquitin-protein ligase parkin ubiquitinated form (human) def: "An E3 ubiquitin-protein ligase parkin (human) that includes at least one ubiquitinated lysine. UniProtKB:O60260, MOD:01148." [PRO:DNx, Reactome:R-HSA-5689094] comment: Category=organism-modification. synonym: "hPRKN/UbiqLys+" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:O60260, MOD:01148" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-5689094 "PR:000048694 located_in GO:0005829" intersection_of: has_part MOD:01148 ! ubiquitinylated lysine intersection_of: PR:O60260 ! E3 ubiquitin-protein ligase parkin (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000038230 name: E3 ubiquitin-protein ligase parkin isoform 1 def: "An E3 ubiquitin-protein ligase parkin that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O60260-1 or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=sequence. synonym: "PRKN/iso:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000012285 ! E3 ubiquitin-protein ligase parkin [Term] id: PR:000038231 name: E3 ubiquitin-protein ligase parkin isoform 2 def: "An E3 ubiquitin-protein ligase parkin that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O60260-2 or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=sequence. synonym: "PRKN/iso:2" EXACT PRO-short-label [PRO:DNx] is_a: PR:000012285 ! E3 ubiquitin-protein ligase parkin [Term] id: PR:O60260 name: E3 ubiquitin-protein ligase parkin (human) def: "An E3 ubiquitin-protein ligase parkin that is encoded in the genome of human." [PRO:DNx, UniProtKB:O60260] comment: Category=organism-gene. synonym: "PRKN" RELATED Gene-based [UniProtKB:O60260] synonym: "PARK2" RELATED Gene-based [UniProtKB:O60260] synonym: "hPRKN" EXACT PRO-short-label [PRO:DNx] synonym: "parkin (human)" EXACT [UniProtKB:O60260] synonym: "parkinson disease protein 2 (human)" EXACT [UniProtKB:O60260] synonym: "parkinson juvenile disease protein 2 (human)" EXACT [UniProtKB:O60260] synonym: "parkin RBR E3 ubiquitin-protein ligase (human)" EXACT [UniProtKB:O60260] xref: Reactome:R-HSA-201579 "PR:O60260 located_in GO:0005829" xref: UniProtKB:O60260 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000012285 ! E3 ubiquitin-protein ligase parkin relationship: has_gene_template HGNC:8607 ! PRKN (human) [Term] id: PR:Q9WVS6-1 name: E3 ubiquitin-protein ligase parkin isoform m1 (mouse) def: "An E3 ubiquitin-protein ligase parkin (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9WVS6-1." [PRO:DNx, UniProtKB:Q9WVS6] comment: Category=organism-sequence. synonym: "mPRKN/iso:m1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9WVS6-1 is_a: PR:Q9WVS6 ! E3 ubiquitin-protein ligase parkin (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:000012285 name: E3 ubiquitin-protein ligase parkin def: "A protein that is a translation product of the human PRKN gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "PRKN" EXACT PRO-short-label [PRO:DNx] synonym: "PARK2" RELATED Gene-based [] synonym: "parkinson disease protein 2" EXACT [] synonym: "parkinson juvenile disease protein 2" EXACT [] synonym: "parkin RBR E3 ubiquitin-protein ligase" EXACT [] is_a: PR:000000001 ! protein