[Term]
id: PR:000012296
name: poly [ADP-ribose] polymerase 2
def: "A protein that is a translation product of the human PARP2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "ARTD2" EXACT []
synonym: "PARP2" EXACT PRO-short-label [PRO:DNx]
synonym: "ADPRT2" RELATED Gene-based []
synonym: "PARP-2" EXACT []
synonym: "ADPRT-2" EXACT []
synonym: "ADPRTL2" RELATED Gene-based []
synonym: "Aspartl2" RELATED Gene-based []
synonym: "pADPRT-2" EXACT []
synonym: "poly[ADP-ribose] synthase 2" EXACT []
synonym: "poly[ADP-ribose] synthetase 2" EXACT []
synonym: "NAD(+) ADP-ribosyltransferase 2" EXACT []
synonym: "DNA ADP-ribosyltransferase PARP2" EXACT []
synonym: "protein poly-ADP-ribosyltransferase PARP2" EXACT []
synonym: "ADP-ribosyltransferase diphtheria toxin-like 2" EXACT []
xref: IUPHARobj:2772
is_a: PR:000000001 ! protein

[Term]
id: PR:Q9UGN5-1
name: poly [ADP-ribose] polymerase 2 isoform h1 (human)
def: "A poly [ADP-ribose] polymerase 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UGN5-1." [PRO:DNx, UniProtKB:Q9UGN5]
comment: Category=organism-sequence.
synonym: "hPARP2/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9UGN5-1
is_a: PR:Q9UGN5 ! poly [ADP-ribose] polymerase 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000048697
name: poly [ADP-ribose] polymerase 2 ADP-ribosylglutamate form (human)
def: "A poly [ADP-ribose] polymerase 2 (human) that includes at least one ADP-ribosylated glutamic acid. UniProtKB:Q9UGN5, MOD:00300." [PRO:DNx, Reactome:R-HSA-5651715]
comment: Category=organism-modification.
synonym: "hPARP2/ADPribGlu+" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9UGN5, MOD:00300" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5651715 "PR:000048697 located_in GO:0005654"
intersection_of: has_part MOD:00300 ! L-glutamyl-5-poly(ADP-ribose)
intersection_of: PR:Q9UGN5 ! poly [ADP-ribose] polymerase 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9UGN5
name: poly [ADP-ribose] polymerase 2 (human)
def: "A poly [ADP-ribose] polymerase 2 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-gene.
synonym: "PARP2" RELATED Gene-based [UniProtKB:Q9UGN5]
synonym: "ADPRT2" RELATED Gene-based [UniProtKB:Q9UGN5]
synonym: "hPARP2" EXACT PRO-short-label [PRO:DNx]
synonym: "ADPRTL2" RELATED Gene-based [UniProtKB:Q9UGN5]
synonym: "hPARP-2" EXACT [UniProtKB:Q9UGN5]
synonym: "ARTD2 (human)" EXACT [UniProtKB:Q9UGN5]
synonym: "PARP-2 (human)" EXACT [UniProtKB:Q9UGN5]
synonym: "ADPRT-2 (human)" EXACT [UniProtKB:Q9UGN5]
synonym: "pADPRT-2 (human)" EXACT [UniProtKB:Q9UGN5]
synonym: "poly[ADP-ribose] synthase 2 (human)" EXACT [UniProtKB:Q9UGN5]
synonym: "NAD(+) ADP-ribosyltransferase 2 (human)" EXACT [UniProtKB:Q9UGN5]
synonym: "DNA ADP-ribosyltransferase PARP2 (human)" EXACT [UniProtKB:Q9UGN5]
synonym: "protein poly-ADP-ribosyltransferase PARP2 (human)" EXACT [UniProtKB:Q9UGN5]
synonym: "ADP-ribosyltransferase diphtheria toxin-like 2 (human)" EXACT [UniProtKB:Q9UGN5]
xref: Reactome:R-HSA-174874 "PR:Q9UGN5 located_in GO:0005654"
xref: UniProtKB:Q9UGN5
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000012296 ! poly [ADP-ribose] polymerase 2
relationship: has_gene_template HGNC:272 ! PARP2 (human)

[Term]
id: PR:Q9UGN5-2
name: poly [ADP-ribose] polymerase 2 isoform h2 (human)
def: "A poly [ADP-ribose] polymerase 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UGN5-2." [PRO:DNx, UniProtKB:Q9UGN5]
comment: Category=organism-sequence.
synonym: "hPARP2/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9UGN5-2
is_a: PR:Q9UGN5 ! poly [ADP-ribose] polymerase 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens