[Term]
id: PR:P29122-6
name: proprotein convertase subtilisin/kexin type 6 isoform hPACE4D (human)
def: "A proprotein convertase subtilisin/kexin type 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29122-6." [PRO:DNx, UniProtKB:P29122]
comment: Category=organism-sequence.
synonym: "hPCSK6/iso:hPACE4D" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P29122-6
is_a: PR:P29122 ! proprotein convertase subtilisin/kexin type 6 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P29122-1
name: proprotein convertase subtilisin/kexin type 6 isoform hPACE4A-I (human)
def: "A proprotein convertase subtilisin/kexin type 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29122-1." [PRO:DNx, UniProtKB:P29122]
comment: Category=organism-sequence.
synonym: "hPCSK6/iso:hPACE4A-I" EXACT PRO-short-label [PRO:DNx]
synonym: "proprotein convertase subtilisin/kexin type 6 isoform PACE4 (human)" EXACT [UniProtKB:P29122]
xref: UniProtKB:P29122-1
is_a: PR:P29122 ! proprotein convertase subtilisin/kexin type 6 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P29122-2
name: proprotein convertase subtilisin/kexin type 6 isoform hPACE4A-II (human)
def: "A proprotein convertase subtilisin/kexin type 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29122-2." [PRO:DNx, UniProtKB:P29122]
comment: Category=organism-sequence.
synonym: "hPCSK6/iso:hPACE4A-II" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P29122-2
is_a: PR:P29122 ! proprotein convertase subtilisin/kexin type 6 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P29122-3
name: proprotein convertase subtilisin/kexin type 6 isoform hPACE4B (human)
def: "A proprotein convertase subtilisin/kexin type 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29122-3." [PRO:DNx, UniProtKB:P29122]
comment: Category=organism-sequence.
synonym: "hPCSK6/iso:hPACE4B" EXACT PRO-short-label [PRO:DNx]
synonym: "proprotein convertase subtilisin/kexin type 6 isoform PACE4.1 (human)" EXACT [UniProtKB:P29122]
xref: UniProtKB:P29122-3
is_a: PR:P29122 ! proprotein convertase subtilisin/kexin type 6 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P29122-4
name: proprotein convertase subtilisin/kexin type 6 isoform hPACE4C (human)
def: "A proprotein convertase subtilisin/kexin type 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29122-4." [PRO:DNx, UniProtKB:P29122]
comment: Category=organism-sequence.
synonym: "hPCSK6/iso:hPACE4C" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P29122-4
is_a: PR:P29122 ! proprotein convertase subtilisin/kexin type 6 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P29122
name: proprotein convertase subtilisin/kexin type 6 (human)
def: "A proprotein convertase subtilisin/kexin type 6 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P29122]
comment: Category=organism-gene.
synonym: "PACE4" RELATED Gene-based [UniProtKB:P29122]
synonym: "PCSK6" RELATED Gene-based [UniProtKB:P29122]
synonym: "hPCSK6" EXACT PRO-short-label [PRO:DNx]
synonym: "SPC4 (human)" EXACT [UniProtKB:P29122]
synonym: "subtilisin/kexin-like protease PACE4 (human)" EXACT [UniProtKB:P29122]
synonym: "subtilisin-like proprotein convertase 4 (human)" EXACT [UniProtKB:P29122]
synonym: "paired basic amino acid cleaving enzyme 4 (human)" EXACT [UniProtKB:P29122]
xref: UniProtKB:P29122
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000012438 ! proprotein convertase subtilisin/kexin type 6
relationship: has_gene_template HGNC:8569 ! PCSK6 (human)

[Term]
id: PR:000056328
name: proprotein convertase subtilisin/kexin type 6 O-glycosylated 1 (human)
def: "A proprotein convertase subtilisin/kexin type 6 (human) that has been O-glycosylated at the residue equivalent to Thr-683 of the amino acid sequence represented by UniProtKB:P29122-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P29122-1, Thr-683, MOD:00005~GNO:G43417UB." [GlyGen:P29122-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hPCSK6/OGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P29122-1, Thr-683, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P29122 ! proprotein convertase subtilisin/kexin type 6 (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P29122-7
name: proprotein convertase subtilisin/kexin type 6 isoform hPACE4E-I (human)
def: "A proprotein convertase subtilisin/kexin type 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29122-7." [PRO:DNx, UniProtKB:P29122]
comment: Category=organism-sequence.
synonym: "hPCSK6/iso:hPACE4E-I" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P29122-7
is_a: PR:P29122 ! proprotein convertase subtilisin/kexin type 6 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P29122-8
name: proprotein convertase subtilisin/kexin type 6 isoform hPACE4E-II (human)
def: "A proprotein convertase subtilisin/kexin type 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29122-8." [PRO:DNx, UniProtKB:P29122]
comment: Category=organism-sequence.
synonym: "hPCSK6/iso:hPACE4E-II" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P29122-8
is_a: PR:P29122 ! proprotein convertase subtilisin/kexin type 6 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000012438
name: proprotein convertase subtilisin/kexin type 6
def: "A subtilisin/kexin-type proprotein convertase that is a translation product of the human PCSK6 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "SPC4" EXACT []
synonym: "PACE4" RELATED Gene-based []
synonym: "PCSK6" EXACT PRO-short-label [PRO:DNx]
synonym: "subtilisin/kexin-like protease PACE4" EXACT []
synonym: "subtilisin-like proprotein convertase 4" EXACT []
synonym: "paired basic amino acid cleaving enzyme 4" EXACT []
xref: IUPHARobj:2386
is_a: PR:000003136 ! subtilisin/kexin-type proprotein convertase

[Term]
id: PR:P29122-5
name: proprotein convertase subtilisin/kexin type 6 isoform hPACE4CS (human)
def: "A proprotein convertase subtilisin/kexin type 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29122-5." [PRO:DNx, UniProtKB:P29122]
comment: Category=organism-sequence.
synonym: "hPCSK6/iso:hPACE4CS" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P29122-5
is_a: PR:P29122 ! proprotein convertase subtilisin/kexin type 6 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens