[Term] id: PR:Q07343-2 name: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform hPDE4B2 (human) def: "A cAMP-specific 3',5'-cyclic phosphodiesterase 4B (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q07343-2." [PRO:DNx, UniProtKB:Q07343] comment: Category=organism-sequence. synonym: "hPDE4B/iso:hPDE4B2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q07343-2 is_a: PR:Q07343 ! cAMP-specific 3',5'-cyclic phosphodiesterase 4B (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q07343-3 name: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform hPDE4B3 (human) def: "A cAMP-specific 3',5'-cyclic phosphodiesterase 4B (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q07343-3." [PRO:DNx, UniProtKB:Q07343] comment: Category=organism-sequence. synonym: "hPDE4B/iso:hPDE4B3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q07343-3 is_a: PR:Q07343 ! cAMP-specific 3',5'-cyclic phosphodiesterase 4B (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q07343 name: cAMP-specific 3',5'-cyclic phosphodiesterase 4B (human) def: "A cAMP-specific 3',5'-cyclic phosphodiesterase 4B that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q07343] comment: Category=organism-gene. synonym: "DPDE4" RELATED Gene-based [UniProtKB:Q07343] synonym: "PDE4B" RELATED Gene-based [UniProtKB:Q07343] synonym: "hPDE4B" EXACT PRO-short-label [PRO:DNx] synonym: "PDE32 (human)" EXACT [UniProtKB:Q07343] xref: Reactome:R-HSA-52385 "PR:Q07343 located_in GO:0005829" xref: UniProtKB:Q07343 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000012473 ! cAMP-specific 3',5'-cyclic phosphodiesterase 4B relationship: has_gene_template HGNC:8781 ! PDE4B (human) [Term] id: PR:000012473 name: cAMP-specific 3',5'-cyclic phosphodiesterase 4B def: "A protein that is a translation product of the human PDE4B gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "DPDE4" RELATED Gene-based [] synonym: "PDE32" EXACT [] synonym: "PDE4B" EXACT PRO-short-label [PRO:DNx] xref: IUPHARobj:1301 is_a: PR:000000001 ! protein [Term] id: PR:Q07343-4 name: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform hPDE4B5 (human) def: "A cAMP-specific 3',5'-cyclic phosphodiesterase 4B (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q07343-4." [PRO:DNx, UniProtKB:Q07343] comment: Category=organism-sequence. synonym: "hPDE4B/iso:hPDE4B5" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q07343-4 is_a: PR:Q07343 ! cAMP-specific 3',5'-cyclic phosphodiesterase 4B (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000048720 name: cAMP-specific 3',5'-cyclic phosphodiesterase 4B phosphorylated 1 (human) def: "A cAMP-specific 3',5'-cyclic phosphodiesterase 4B (human) that has been phosphorylated on the residue at the position equivalent to Ser-133 of the amino acid sequence represented by UniProtKB:Q07343. UniProtKB:Q07343, Ser-133, MOD:00046." [PRO:DAN, Reactome:R-HSA-177290] comment: Category=organism-modification. Note: The modified site indicated here (Ser-133) is referred to as Ser-54 in the literature using the rat sequence. [PRO:DAN, PMID:8663227] synonym: "hPDE4B/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q07343, Ser-133, MOD:00046" EXACT PRO-proteoform-std [PRO:DAN] xref: Reactome:R-HSA-177290 "PR:000048720 located_in GO:0005829" is_a: PR:Q07343 ! cAMP-specific 3',5'-cyclic phosphodiesterase 4B (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q07343-1 name: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform PDE4B1 (human) def: "A cAMP-specific 3',5'-cyclic phosphodiesterase 4B (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q07343-1." [PRO:DNx, UniProtKB:Q07343] comment: Category=organism-sequence. Requested by=PubChem. synonym: "hPDE4B/iso:PDE4B1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q07343-1 is_a: PR:Q07343 ! cAMP-specific 3',5'-cyclic phosphodiesterase 4B (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens