[Term]
id: PR:000012737
name: serine/threonine-protein kinase PINK1, mitochondrial
def: "A protein that is a translation product of the human PINK1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "BRPK" EXACT []
synonym: "PINK1" EXACT PRO-short-label [PRO:DNx]
synonym: "PTEN-induced putative kinase protein 1" EXACT []
xref: IUPHARobj:2161
is_a: PR:000000001 ! protein

[Term]
id: PR:000048774
name: serine/threonine-protein kinase PINK1, mitochondrial, transit peptide removed form (human)
def: "A serine/threonine-protein kinase PINK1, mitochondrial (human) that has had the transit peptide removed. UniProtKB:Q9BXM7, 78-581." [PRO:DNx, Reactome:R-HSA-5205637, Reactome:R-HSA-5205653, Reactome:R-HSA-5205671]
comment: Category=organism-modification.
synonym: "PRO_0000024369" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hPINK1/TransPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9BXM7, 78-581" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5205637 "PR:000048774 located_in GO:0005829"
xref: Reactome:R-HSA-5205653 "PR:000048774 located_in GO:0005741"
xref: Reactome:R-HSA-5205671 "PR:000048774 located_in GO:0005758"
intersection_of: PR:Q9BXM7 ! serine/threonine-protein kinase PINK1, mitochondrial (human)
intersection_of: lacks_part SO:0000725 ! transit_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9BXM7
name: serine/threonine-protein kinase PINK1, mitochondrial (human)
def: "A serine/threonine-protein kinase PINK1, mitochondrial that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9BXM7]
comment: Category=organism-gene.
synonym: "PINK1" RELATED Gene-based [UniProtKB:Q9BXM7]
synonym: "hPINK1" EXACT PRO-short-label [PRO:DNx]
synonym: "BRPK (human)" EXACT [UniProtKB:Q9BXM7]
synonym: "PTEN-induced putative kinase protein 1 (human)" EXACT [UniProtKB:Q9BXM7]
xref: DTO:03100420
xref: UniProtKB:Q9BXM7
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000012737 ! serine/threonine-protein kinase PINK1, mitochondrial
relationship: has_gene_template HGNC:14581 ! PINK1 (human)

[Term]
id: PR:000046048
name: serine/threonine-protein kinase PINK1, mitochondrial phosphorylated 1 (human)
def: "A serine/threonine-protein kinase PINK1, mitochondrial (human) that has been phosphorylated on the residue at the position equivalent to Thr-313 of the amino acid sequence represented by UniProtKB:Q9BXM7-1. Example: UniProtKB:Q9BXM7-1, Thr-313, MOD:00047." [PMID:22238344, iPTMnet:Q9BXM7]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:22238344). Status=unreviewed.
synonym: "hPINK1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9BXM7-1, Thr-313, MOD:00047" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q9BXM7 ! serine/threonine-protein kinase PINK1, mitochondrial (human)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q99MQ3
name: serine/threonine-protein kinase PINK1, mitochondrial (mouse)
def: "A serine/threonine-protein kinase PINK1, mitochondrial that is encoded in the genome of mouse." [OMA:Q99MQ3, PRO:DNx]
comment: Category=organism-gene.
synonym: "Pink1" RELATED Gene-based [UniProtKB:Q99MQ3]
synonym: "mPINK1" EXACT PRO-short-label [PRO:DNx]
synonym: "BRPK (mouse)" EXACT [UniProtKB:Q99MQ3]
synonym: "PTEN-induced putative kinase protein 1 (mouse)" EXACT [UniProtKB:Q99MQ3]
xref: UniProtKB:Q99MQ3
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000012737 ! serine/threonine-protein kinase PINK1, mitochondrial
relationship: has_gene_template MGI:1916193 ! Pink1 (mouse)

[Term]
id: PR:Q9BXM7-2
name: serine/threonine-protein kinase PINK1, mitochondrial isoform h2 (human)
def: "A serine/threonine-protein kinase PINK1, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BXM7-2." [PRO:DNx, UniProtKB:Q9BXM7]
comment: Category=organism-sequence.
synonym: "hPINK1/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9BXM7-2
is_a: PR:Q9BXM7 ! serine/threonine-protein kinase PINK1, mitochondrial (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q09298
name: serine/threonine-protein kinase pink-1, mitochondrial (worm)
def: "A serine/threonine-protein kinase PINK1, mitochondrial that is encoded in the genome of worm." [PANTHER:PTHR22972:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "pink-1" RELATED Gene-based [UniProtKB:Q09298]
synonym: "EEED8.9" RELATED Gene-based [UniProtKB:Q09298]
synonym: "PINK1 (worm)" EXACT PRO-short-label [PRO:DNx]
synonym: "PTEN-induced kinase 1 homolog (worm)" EXACT [UniProtKB:Q09298]
xref: UniProtKB:Q09298
intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans
intersection_of: PR:000012737 ! serine/threonine-protein kinase PINK1, mitochondrial
relationship: has_gene_template WormBase:WBGene00017137 ! pink-1 (worm)

[Term]
id: PR:Q9BXM7-1
name: serine/threonine-protein kinase PINK1, mitochondrial isoform h1 (human)
def: "A serine/threonine-protein kinase PINK1, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BXM7-1." [PRO:DNx, UniProtKB:Q9BXM7]
comment: Category=organism-sequence.
synonym: "hPINK1/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9BXM7-1
is_a: PR:Q9BXM7 ! serine/threonine-protein kinase PINK1, mitochondrial (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens