[Term] id: PR:Q16512-1 name: serine/threonine-protein kinase N1 isoform h1 (human) def: "A serine/threonine-protein kinase N1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q16512-1." [PRO:DNx, UniProtKB:Q16512] comment: Category=organism-sequence. synonym: "hPKN1/iso:h1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q16512-1 is_a: PR:Q16512 ! serine/threonine-protein kinase N1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q16512-2 name: serine/threonine-protein kinase N1 isoform h2 (human) def: "A serine/threonine-protein kinase N1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q16512-2." [PRO:DNx, UniProtKB:Q16512] comment: Category=organism-sequence. synonym: "hPKN1/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q16512-2 is_a: PR:Q16512 ! serine/threonine-protein kinase N1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q16512-3 name: serine/threonine-protein kinase N1 isoform h3 (human) def: "A serine/threonine-protein kinase N1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q16512-3." [PRO:DNx, UniProtKB:Q16512] comment: Category=organism-sequence. synonym: "hPKN1/iso:h3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q16512-3 is_a: PR:Q16512 ! serine/threonine-protein kinase N1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000012785 name: serine/threonine-protein kinase N1 def: "A protein that is a translation product of the human PKN1 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "PKN" RELATED Gene-based [] synonym: "PAK1" RELATED Gene-based [] synonym: "PKN1" EXACT PRO-short-label [PRO:DNx] synonym: "PRK1" RELATED Gene-based [] synonym: "PRKCL1" RELATED Gene-based [] synonym: "protein kinase C-like 1" BROAD [PRO:DNx] synonym: "protein kinase PKN-alpha" EXACT [] synonym: "protein kinase C-like PKN" EXACT [] synonym: "protein-kinase C-related kinase 1" EXACT [] synonym: "serine-threonine protein kinase N" EXACT [] xref: IUPHARobj:1520 is_a: PR:000000001 ! protein [Term] id: PR:000048785 name: serine/threonine-protein kinase N1, initiator methionine removed phosphorylated 1 (human) def: "A serine/threonine-protein kinase N1 (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphothreonine at position 774 of the amino acid sequence represented by UniProtKB:Q16512. UniProtKB:Q16512, 2-942, Thr-774, MOD:00047." [PRO:DNx, Reactome:R-HSA-5623651, Reactome:R-HSA-5625721] comment: Category=organism-modification. synonym: "hPKN1/InitMet-/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000055719, Thr-774, MOD:00047" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q16512, 2-942, Thr-774, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-5625721 "PR:000048785 located_in GO:0005654" xref: Reactome:R-HSA-5623651 "PR:000048785 located_in GO:0005829" is_a: PR:Q16512 ! serine/threonine-protein kinase N1 (human) relationship: has_part MOD:00047 ! O-phospho-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000048784 name: serine/threonine-protein kinase N1, initiator methionine removed form (human) def: "A serine/threonine-protein kinase N1 (human) that has had the initiator methionine removed. UniProtKB:Q16512, 2-942." [PRO:DNx, Reactome:R-HSA-5623613] comment: Category=organism-modification. synonym: "PRO_0000055719" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hPKN1/InitMet-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q16512, 2-942" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-5623613 "PR:000048784 located_in GO:0005829" intersection_of: lacks_part PR:000021937 ! initiator methionine intersection_of: PR:Q16512 ! serine/threonine-protein kinase N1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q16512 name: serine/threonine-protein kinase N1 (human) def: "A serine/threonine-protein kinase N1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q16512] comment: Category=organism-gene. synonym: "PKN" RELATED Gene-based [UniProtKB:Q16512] synonym: "PAK1" RELATED Gene-based [UniProtKB:Q16512] synonym: "PKN1" RELATED Gene-based [UniProtKB:Q16512] synonym: "PRK1" RELATED Gene-based [UniProtKB:Q16512] synonym: "hPKN1" EXACT PRO-short-label [PRO:DNx] synonym: "PRKCL1" RELATED Gene-based [UniProtKB:Q16512] synonym: "PAK-1 (human)" BROAD [UniProtKB:Q16512] synonym: "protein kinase C-like 1 (human)" EXACT [UniProtKB:Q16512] synonym: "protein kinase PKN-alpha (human)" EXACT [UniProtKB:Q16512] synonym: "protein kinase C-like PKN (human)" EXACT [UniProtKB:Q16512] synonym: "protease-activated kinase 1 (human)" EXACT [UniProtKB:Q16512] synonym: "protein-kinase C-related kinase 1 (human)" EXACT [UniProtKB:Q16512] synonym: "serine-threonine protein kinase N (human)" EXACT [UniProtKB:Q16512] xref: DTO:03100427 xref: UniProtKB:Q16512 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000012785 ! serine/threonine-protein kinase N1 relationship: has_gene_template HGNC:9405 ! PKN1 (human)