[Term] id: PR:P35354 name: prostaglandin G/H synthase 2 (human) def: "A prostaglandin G/H synthase 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P35354] comment: Category=organism-gene. synonym: "COX2" RELATED Gene-based [UniProtKB:P35354] synonym: "PTGS2" RELATED Gene-based [UniProtKB:P35354] synonym: "hPTGS2" EXACT PRO-short-label [PRO:DNx] synonym: "COX-2 (human)" EXACT [UniProtKB:P35354] synonym: "PGHS-2 (human)" EXACT [UniProtKB:P35354] synonym: "PHS II (human)" EXACT [UniProtKB:P35354] synonym: "PGH synthase 2 (human)" EXACT [UniProtKB:P35354] synonym: "cyclooxygenase-2 (human)" EXACT [UniProtKB:P35354] synonym: "prostaglandin H2 synthase 2 (human)" EXACT [UniProtKB:P35354] synonym: "prostaglandin-endoperoxide synthase 2 (human)" EXACT [UniProtKB:P35354] xref: UniProtKB:P35354 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000013428 ! prostaglandin G/H synthase 2 relationship: has_gene_template HGNC:9605 ! PTGS2 (human) [Term] id: PR:000013428 name: prostaglandin G/H synthase 2 def: "A protein that is a translation product of the human PTGS2 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "COX2" RELATED Gene-based [] synonym: "COX-2" EXACT [] synonym: "PES-2" EXACT [] synonym: "PTGS2" EXACT PRO-short-label [PRO:DNx] synonym: "Tis10" RELATED Gene-based [] synonym: "PGHS-2" EXACT [] synonym: "PHS II" EXACT [] synonym: "Pghs-b" RELATED Gene-based [] synonym: "gripghs" EXACT [] synonym: "TIS10 protein" EXACT [] synonym: "PGH synthase 2" EXACT [] synonym: "cyclooxygenase-2" EXACT [] synonym: "prostaglandin H2 synthase 2" EXACT [] synonym: "prostaglandin-endoperoxide synthase 2" EXACT [] synonym: "glucocorticoid-regulated inflammatory cyclooxygenase" EXACT [] synonym: "macrophage activation-associated marker protein P71/73" EXACT [] xref: IUPHARobj:1376 is_a: PR:000000001 ! protein [Term] id: PR:P35354-1 name: prostaglandin G/H synthase 2 isoform 1 (human) def: "A prostaglandin G/H synthase 2 isoform 1 that is encoded in the genome of human." [PRO:DNx] comment: Category=organism-sequence. synonym: "hPTGS2/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P35354-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000039332 ! prostaglandin G/H synthase 2 isoform 1 [Term] id: PR:000048946 name: prostaglandin G/H synthase 2, signal peptide removed form (human) def: "A prostaglandin G/H synthase 2 (human) that has had the signal peptide removed. UniProtKB:P35354, 18-604." [PRO:DNx, Reactome:R-HSA-61605] comment: Category=organism-modification. synonym: "PRO_0000023875" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hPTGS2/SigPep-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P35354, 18-604" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-61605 "PR:000048946 located_in GO:0005789" intersection_of: PR:P35354 ! prostaglandin G/H synthase 2 (human) intersection_of: lacks_part SO:0000418 ! signal_peptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens