[Term] id: PR:000048959 name: tyrosine-protein phosphatase non-receptor type 11 phosphorylated 1 (human) def: "A tyrosine-protein phosphatase non-receptor type 11 (human) that has been phosphorylated on the residue at the position equivalent to Tyr-546 of the amino acid sequence represented by UniProtKB:Q06124. UniProtKB:Q06124, Tyr-546, MOD:00048." [PRO:DNx, Reactome:R-HSA-1369081] comment: Category=organism-modification. synonym: "hPTPN11/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q06124, Tyr-546, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-1369081 "PR:000048959 located_in GO:0005829" is_a: PR:Q06124 ! tyrosine-protein phosphatase non-receptor type 11 (human) relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q06124-2 name: tyrosine-protein phosphatase non-receptor type 11 isoform 2 (human) def: "A tyrosine-protein phosphatase non-receptor type 11 isoform 2 that is encoded in the genome of human." [PRO:DNx] comment: Category=organism-sequence. synonym: "hPTPN11/iso:2" EXACT PRO-short-label [PRO:DNx] synonym: "tyrosine-protein phosphatase non-receptor type 11 isoform PTP2C (human)" EXACT [UniProtKB:Q06124] xref: UniProtKB:Q06124-2 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000040296 ! tyrosine-protein phosphatase non-receptor type 11 isoform 2 [Term] id: PR:000013449 name: tyrosine-protein phosphatase non-receptor type 11 def: "A protein that is a translation product of the human PTPN11 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "shp2" EXACT [] synonym: "PTP2C" RELATED Gene-based [] synonym: "SHP-2" EXACT [] synonym: "PTP-1D" EXACT [] synonym: "PTP-2C" EXACT [] synonym: "PTPN11" EXACT PRO-short-label [PRO:DNx] synonym: "SHPTP2" RELATED Gene-based [] synonym: "SH-PTP2" EXACT [] synonym: "SH-PTP3" EXACT [] synonym: "protein-tyrosine phosphatase 1D" EXACT [] synonym: "protein-tyrosine phosphatase 2C" EXACT [] synonym: "protein-tyrosine phosphatase SYP" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:Q06124-1 name: tyrosine-protein phosphatase non-receptor type 11 isoform 1 (human) def: "A tyrosine-protein phosphatase non-receptor type 11 isoform 1 that is encoded in the genome of human." [PRO:DNx] comment: Category=organism-sequence. synonym: "hPTPN11/iso:1" EXACT PRO-short-label [PRO:DNx] synonym: "tyrosine-protein phosphatase non-receptor type 11 isoform PTP2Ci (human)" EXACT [UniProtKB:Q06124] xref: UniProtKB:Q06124-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000040295 ! tyrosine-protein phosphatase non-receptor type 11 isoform 1 [Term] id: PR:000048960 name: tyrosine-protein phosphatase non-receptor type 11 phosphorylated 2 (human) def: "A tyrosine-protein phosphatase non-receptor type 11 (human) that has been post-translationally modified to include phosphotyrosine at positions 546 and 584 of the amino acid sequence represented by UniProtKB:Q06124. UniProtKB:Q06124, Tyr-546/Tyr-584, MOD:00048." [PRO:DNx, Reactome:R-HSA-162573] comment: Category=organism-modification. synonym: "hPTPN11/Phos:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q06124, Tyr-546/Tyr-584, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-162573 "PR:000048960 located_in GO:0005829" is_a: PR:Q06124 ! tyrosine-protein phosphatase non-receptor type 11 (human) relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q06124-3 name: tyrosine-protein phosphatase non-receptor type 11 isoform h3 (human) def: "A tyrosine-protein phosphatase non-receptor type 11 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q06124-3." [PRO:DNx, UniProtKB:Q06124] comment: Category=organism-sequence. synonym: "hPTPN11/iso:h3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q06124-3 is_a: PR:Q06124 ! tyrosine-protein phosphatase non-receptor type 11 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q06124 name: tyrosine-protein phosphatase non-receptor type 11 (human) def: "A tyrosine-protein phosphatase non-receptor type 11 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q06124] comment: Category=organism-gene. synonym: "PTP2C" RELATED Gene-based [UniProtKB:Q06124] synonym: "PTPN11" RELATED Gene-based [UniProtKB:Q06124] synonym: "SHPTP2" RELATED Gene-based [UniProtKB:Q06124] synonym: "hPTPN11" EXACT PRO-short-label [PRO:DNx] synonym: "Shp2 (human)" EXACT [UniProtKB:Q06124] synonym: "SHP-2 (human)" EXACT [UniProtKB:Q06124] synonym: "PTP-1D (human)" EXACT [UniProtKB:Q06124] synonym: "PTP-2C (human)" EXACT [UniProtKB:Q06124] synonym: "SH-PTP2 (human)" EXACT [UniProtKB:Q06124] synonym: "SH-PTP3 (human)" EXACT [UniProtKB:Q06124] synonym: "protein-tyrosine phosphatase 1D (human)" EXACT [UniProtKB:Q06124] synonym: "protein-tyrosine phosphatase 2C (human)" EXACT [UniProtKB:Q06124] xref: Reactome:R-HSA-162563 "PR:Q06124 located_in GO:0005829" xref: Reactome:R-HSA-8937745 "PR:Q06124 located_in GO:0005654" xref: UniProtKB:Q06124 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000013449 ! tyrosine-protein phosphatase non-receptor type 11 relationship: has_gene_template HGNC:9644 ! PTPN11 (human)