[Term]
id: PR:000039215
name: tyrosine-protein phosphatase non-receptor type 6 isoform 1
def: "A tyrosine-protein phosphatase non-receptor type 6 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29350-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "PTPN6/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000013461 ! tyrosine-protein phosphatase non-receptor type 6

[Term]
id: PR:000039217
name: tyrosine-protein phosphatase non-receptor type 6 isoform 3
def: "A tyrosine-protein phosphatase non-receptor type 6 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29350-3 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "PTPN6/iso:3" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000013461 ! tyrosine-protein phosphatase non-receptor type 6

[Term]
id: PR:000039216
name: tyrosine-protein phosphatase non-receptor type 6 isoform 2
def: "A tyrosine-protein phosphatase non-receptor type 6 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29350-2 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "PTPN6/iso:2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000013461 ! tyrosine-protein phosphatase non-receptor type 6

[Term]
id: PR:P29350
name: tyrosine-protein phosphatase non-receptor type 6 (human)
def: "A tyrosine-protein phosphatase non-receptor type 6 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P29350]
comment: Category=organism-gene.
synonym: "HCP" RELATED Gene-based [UniProtKB:P29350]
synonym: "PTP1C" RELATED Gene-based [UniProtKB:P29350]
synonym: "PTPN6" RELATED Gene-based [UniProtKB:P29350]
synonym: "hPTPN6" EXACT PRO-short-label [PRO:DNx]
synonym: "PTP-1C (human)" EXACT [UniProtKB:P29350]
synonym: "SH-PTP1 (human)" EXACT [UniProtKB:P29350]
synonym: "protein-tyrosine phosphatase 1C (human)" EXACT [UniProtKB:P29350]
synonym: "protein-tyrosine phosphatase SHP-1 (human)" EXACT [UniProtKB:P29350]
synonym: "hematopoietic cell protein-tyrosine phosphatase (human)" EXACT [UniProtKB:P29350]
xref: Reactome:R-HSA-197938 "PR:P29350 located_in GO:0005829"
xref: Reactome:R-HSA-6806315 "PR:P29350 located_in GO:0005576"
xref: Reactome:R-HSA-6799641 "PR:P29350 located_in GO:0035580"
xref: Reactome:R-HSA-6800952 "PR:P29350 located_in GO:1904724"
xref: Reactome:R-HSA-9008911 "PR:P29350 located_in GO:0005654"
xref: UniProtKB:P29350
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000013461 ! tyrosine-protein phosphatase non-receptor type 6
relationship: has_gene_template HGNC:9658 ! PTPN6 (human)

[Term]
id: PR:P29350-4
name: tyrosine-protein phosphatase non-receptor type 6 isoform h4 (human)
def: "A tyrosine-protein phosphatase non-receptor type 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29350-4." [PRO:DNx, UniProtKB:P29350]
comment: Category=organism-sequence.
synonym: "hPTPN6/iso:h4" EXACT PRO-short-label [PRO:DNx]
synonym: "tyrosine-protein phosphatase non-receptor type 6 isoform 70-kDa (human)" EXACT [UniProtKB:P29350]
synonym: "tyrosine-protein phosphatase non-receptor type 6 isoform SHP-1L (human)" EXACT [UniProtKB:P29350]
xref: UniProtKB:P29350-4
is_a: PR:P29350 ! tyrosine-protein phosphatase non-receptor type 6 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P81718
name: tyrosine-protein phosphatase non-receptor type 6 (rat)
def: "A tyrosine-protein phosphatase non-receptor type 6 that is encoded in the genome of rat." [PANTHER:PTHR19134:SF65, PRO:DNx]
comment: Category=organism-gene.
synonym: "Ptph6" RELATED Gene-based [UniProtKB:P81718]
synonym: "Ptpn6" RELATED Gene-based [UniProtKB:P81718]
synonym: "rPTPN6" EXACT PRO-short-label [PRO:DNx]
synonym: "protein-tyrosine phosphatase SHP-1 (rat)" EXACT [UniProtKB:P81718]
xref: UniProtKB:P81718
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000013461 ! tyrosine-protein phosphatase non-receptor type 6
relationship: has_gene_template RGD:620660 ! Ptpn6 (rat)

[Term]
id: PR:P29350-1
name: tyrosine-protein phosphatase non-receptor type 6 isoform 1 (human)
def: "A tyrosine-protein phosphatase non-receptor type 6 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hPTPN6/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "tyrosine-protein phosphatase non-receptor type 6 isoform Long (human)" EXACT [UniProtKB:P29350]
xref: UniProtKB:P29350-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000039215 ! tyrosine-protein phosphatase non-receptor type 6 isoform 1

[Term]
id: PR:P29350-3
name: tyrosine-protein phosphatase non-receptor type 6 isoform 2 (human)
def: "A tyrosine-protein phosphatase non-receptor type 6 isoform 3 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hPTPN6/iso:2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P29350-3
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000039217 ! tyrosine-protein phosphatase non-receptor type 6 isoform 3

[Term]
id: PR:P29350-2
name: tyrosine-protein phosphatase non-receptor type 6 isoform 3 (human)
def: "A tyrosine-protein phosphatase non-receptor type 6 isoform 2 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hPTPN6/iso:3" EXACT PRO-short-label [PRO:DNx]
synonym: "tyrosine-protein phosphatase non-receptor type 6 isoform Short (human)" EXACT [UniProtKB:P29350]
xref: UniProtKB:P29350-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000039216 ! tyrosine-protein phosphatase non-receptor type 6 isoform 2

[Term]
id: PR:000045738
name: tyrosine-protein phosphatase non-receptor type 6 phosphorylated 1 (human)
def: "A tyrosine-protein phosphatase non-receptor type 6 (human) that has been phosphorylated on the residue at the position equivalent to Ser-591 of the amino acid sequence represented by UniProtKB:P29350-1. Example: UniProtKB:P29350-1, Ser-591, MOD:00046." [PMID:15269224, iPTMnet:P29350]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:15269224). Status=unreviewed.
synonym: "hPTPN6/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P29350-1, Ser-591, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P29350 ! tyrosine-protein phosphatase non-receptor type 6 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P29351
name: tyrosine-protein phosphatase non-receptor type 6 (mouse)
def: "A tyrosine-protein phosphatase non-receptor type 6 that is encoded in the genome of mouse." [OMA:P29351, PRO:DNx]
comment: Category=organism-gene.
synonym: "Hcp" RELATED Gene-based [UniProtKB:P29351]
synonym: "Hcph" RELATED Gene-based [UniProtKB:P29351]
synonym: "Ptp1C" RELATED Gene-based [UniProtKB:P29351]
synonym: "Ptpn6" RELATED Gene-based [UniProtKB:P29351]
synonym: "mPTPN6" EXACT PRO-short-label [PRO:DNx]
synonym: "SHP-1 (mouse)" EXACT [UniProtKB:P29351]
synonym: "PTP-1C (mouse)" EXACT [UniProtKB:P29351]
synonym: "70Z-SHP (mouse)" EXACT [UniProtKB:P29351]
synonym: "SH-PTP1 (mouse)" EXACT [UniProtKB:P29351]
synonym: "PTPTY-42 (mouse)" EXACT [UniProtKB:P29351]
synonym: "protein-tyrosine phosphatase 1C (mouse)" EXACT [UniProtKB:P29351]
synonym: "hematopoietic cell protein-tyrosine phosphatase (mouse)" EXACT [UniProtKB:P29351]
xref: UniProtKB:P29351
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000013461 ! tyrosine-protein phosphatase non-receptor type 6
relationship: has_gene_template MGI:96055 ! Ptpn6 (mouse)

[Term]
id: PR:P29351-3
name: tyrosine-protein phosphatase non-receptor type 6 isoform 3 (mouse)
def: "A tyrosine-protein phosphatase non-receptor type 6 isoform 2 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mPTPN6/iso:3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P29351-3
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000039216 ! tyrosine-protein phosphatase non-receptor type 6 isoform 2

[Term]
id: PR:P29351-1
name: tyrosine-protein phosphatase non-receptor type 6 isoform 1 (mouse)
def: "A tyrosine-protein phosphatase non-receptor type 6 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mPTPN6/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P29351-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000039215 ! tyrosine-protein phosphatase non-receptor type 6 isoform 1

[Term]
id: PR:P29351-2
name: tyrosine-protein phosphatase non-receptor type 6 isoform 2 (mouse)
def: "A tyrosine-protein phosphatase non-receptor type 6 isoform 3 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mPTPN6/iso:2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P29351-2
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000039217 ! tyrosine-protein phosphatase non-receptor type 6 isoform 3

[Term]
id: PR:000013461
name: tyrosine-protein phosphatase non-receptor type 6
def: "A protein that is a translation product of the human PTPN6 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "HCP" RELATED Gene-based []
synonym: "Hcph" RELATED Gene-based []
synonym: "PTP1C" RELATED Gene-based []
synonym: "PTPN6" EXACT PRO-short-label [PRO:DNx]
synonym: "SHP-1" EXACT []
synonym: "PTP-1C" EXACT []
synonym: "70Z-SHP" EXACT []
synonym: "SH-PTP1" EXACT []
synonym: "PTPTY-42" EXACT []
synonym: "protein-tyrosine phosphatase 1C" EXACT []
synonym: "protein-tyrosine phosphatase SHP-1" EXACT []
synonym: "hematopoietic cell protein-tyrosine phosphatase" EXACT []
is_a: PR:000000001 ! protein