[Term]
id: PR:P46060
name: Ran GTPase-activating protein 1 (human)
def: "A Ran GTPase-activating protein 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P46060]
comment: Category=organism-gene.
synonym: "SD" RELATED Gene-based [UniProtKB:P46060]
synonym: "RANGAP1" RELATED Gene-based [UniProtKB:P46060]
synonym: "KIAA1835" RELATED Gene-based [UniProtKB:P46060]
synonym: "hRANGAP1" EXACT PRO-short-label [PRO:DNx]
synonym: "RanGAP1 (human)" EXACT [UniProtKB:P46060]
xref: UniProtKB:P46060
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000013717 ! Ran GTPase-activating protein 1
relationship: has_gene_template HGNC:9854 ! RANGAP1 (human)

[Term]
id: PR:000013717
name: Ran GTPase-activating protein 1
def: "A protein that is a translation product of the human RANGAP1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "SD" RELATED Gene-based []
synonym: "Fug1" RELATED Gene-based []
synonym: "RANGAP1" EXACT PRO-short-label [PRO:DNx]
synonym: "RanGAP1" EXACT []
synonym: "KIAA1835" RELATED Gene-based []
is_a: PR:000000001 ! protein

[Term]
id: PR:000049011
name: Ran GTPase-activating protein 1, initiator methionine removed form (human)
def: "A Ran GTPase-activating protein 1 (human) that has had the initiator methionine removed. UniProtKB:P46060, 2-587." [PRO:DNx, Reactome:R-HSA-167661, Reactome:R-HSA-376255]
comment: Category=organism-modification.
synonym: "PRO_0000056737" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hRANGAP1/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P46060, 2-587" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-167661 "PR:000049011 located_in GO:0005635"
xref: Reactome:R-HSA-376255 "PR:000049011 located_in GO:0005829"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:P46060 ! Ran GTPase-activating protein 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000049012
name: Ran GTPase-activating protein 1, initiator methionine removed sumoylated 1 (human)
def: "A Ran GTPase-activating protein 1 (human) that has had the initiator methionine removed and has been post-translationally modified to include sumoylated lysine at position 524 of the amino acid sequence represented by UniProtKB:P46060. UniProtKB:P46060, 2-587, Lys-524, MOD:01149." [PRO:DNx, Reactome:R-HSA-3000416]
comment: Category=organism-modification.
synonym: "hRANGAP1/InitMet-/Sumo:1" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000056737, Lys-524, MOD:01149" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P46060, 2-587, Lys-524, MOD:01149" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-3000416 "PR:000049012 located_in GO:0005635"
is_a: PR:P46060 ! Ran GTPase-activating protein 1 (human)
relationship: has_part MOD:01149 ! sumoylated lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part PR:000021937 ! initiator methionine