[Term] id: PR:P11416-2 name: retinoic acid receptor alpha isoform Alpha-2 (mouse) def: "A retinoic acid receptor alpha isoform 2 that is encoded in the genome of mouse." [PRO:HJD] comment: Category=organism-sequence. synonym: "mRARA/iso:Alpha-2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P11416-2 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000022010 ! retinoic acid receptor alpha isoform 2 [Term] id: PR:P11416-1 name: retinoic acid receptor alpha isoform 1 (mouse) def: "A retinoic acid receptor alpha isoform 1 that is encoded in the genome of mouse." [PRO:HJD] comment: Category=organism-sequence. synonym: "mRARalpha1" EXACT [] synonym: "mRARA/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P11416-1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000022009 ! retinoic acid receptor alpha isoform 1 [Term] id: PR:P10276-1 name: retinoic acid receptor alpha isoform 1 (human) def: "A retinoic acid receptor alpha isoform 1 that is encoded in the genome of human." [PRO:CNA] comment: Category=organism-sequence. Requested by=PubChem. synonym: "hRARalpha1" EXACT [] synonym: "hRARA/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P10276-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000022009 ! retinoic acid receptor alpha isoform 1 [Term] id: PR:P10276-2 name: retinoic acid receptor alpha isoform Alpha-2 (human) def: "A retinoic acid receptor alpha isoform 2 that is encoded in the genome of human." [PRO:HJD] comment: Category=organism-sequence. synonym: "hRARA/iso:Alpha-2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P10276-2 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000022010 ! retinoic acid receptor alpha isoform 2 [Term] id: PR:P10276-3 name: retinoic acid receptor alpha isoform hAlpha-1-deltaBC (human) def: "A retinoic acid receptor alpha (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10276-3." [PRO:DNx, UniProtKB:P10276] comment: Category=organism-sequence. synonym: "hRARA/iso:hAlpha-1-deltaBC" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P10276-3 is_a: PR:P10276 ! retinoic acid receptor alpha (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000026077 name: retinoic acid receptor alpha isoform 1 phosphorylated 1 (mouse) def: "A retinoic acid receptor alpha isoform 1 phosphorylated 1 in mouse. UniProtKB:P11416-1, Ser-77, MOD:00046." [PMID:9230306, PRO:DAN, PRO:HJD] comment: Category=organism-modification. synonym: "mRARA/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P11416-1, Ser-77, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000026076 ! retinoic acid receptor alpha isoform 1 phosphorylated 1 relationship: has_part MOD:00046 ! O-phospho-L-serine [Term] id: PR:000026076 name: retinoic acid receptor alpha isoform 1 phosphorylated 1 def: "A retinoic acid receptor alpha isoform 1 that has been phosphorylated in the N-terminal AF-1 domain by CDK7. Example: UniProtKB:P11416-1, Ser-77, MOD:00046." [PMID:16275922, PMID:9230306, PRO:DAN, PRO:HJD] comment: Category=modification. synonym: "RARA/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000022009 ! retinoic acid receptor alpha isoform 1 relationship: has_part MOD:00046 ! O-phospho-L-serine [Term] id: PR:000013736 name: retinoic acid receptor alpha def: "A protein that is a translation product of the human RARA gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "RARA" EXACT PRO-short-label [PRO:DNx] synonym: "NR1B1" RELATED Gene-based [] synonym: "RARalpha" EXACT [] synonym: "RAR-alpha" EXACT [] synonym: "nuclear receptor subfamily 1 group B member 1" EXACT [] xref: IUPHARobj:590 is_a: PR:000000001 ! protein [Term] id: PR:000022009 name: retinoic acid receptor alpha isoform 1 def: "A retinoic acid receptor alpha that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P11416-1 or a 1:1 ortholog thereof." [PRO:HJD] comment: Category=sequence. synonym: "RARA/iso:1" EXACT PRO-short-label [PRO:DNx] synonym: "retinoic acid receptor isoform alpha-1" EXACT [] is_a: PR:000013736 ! retinoic acid receptor alpha [Term] id: PR:P11416 name: retinoic acid receptor alpha (mouse) def: "A retinoic acid receptor alpha that is encoded in the genome of mouse." [OMA:P11416, PRO:DNx] comment: Category=organism-gene. synonym: "Rara" RELATED Gene-based [UniProtKB:P11416] synonym: "Nr1b1" RELATED Gene-based [UniProtKB:P11416] synonym: "mRARA" EXACT PRO-short-label [PRO:DNx] synonym: "RAR-alpha (mouse)" EXACT [UniProtKB:P11416] synonym: "nuclear receptor subfamily 1 group B member 1 (mouse)" EXACT [UniProtKB:P11416] xref: UniProtKB:P11416 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000013736 ! retinoic acid receptor alpha relationship: has_gene_template MGI:97856 ! Rara (mouse) [Term] id: PR:Q90271 name: retinoic acid receptor alpha-A (zebrafish) def: "A retinoic acid receptor alpha that is encoded in the genome of zebrafish." [OMA:Q90271, PRO:DNx] comment: Category=organism-gene. synonym: "raraa" RELATED Gene-based [UniProtKB:Q90271] synonym: "nr1b1a" RELATED Gene-based [UniProtKB:Q90271] synonym: "rara2a" RELATED Gene-based [UniProtKB:Q90271] synonym: "z-RARA" EXACT PRO-short-label [PRO:DNx] synonym: "zRAR alpha" EXACT [UniProtKB:Q90271] synonym: "zgc:109797" RELATED Gene-based [UniProtKB:Q90271] synonym: "RAR-alpha-A (zebrafish)" EXACT [UniProtKB:Q90271] synonym: "RAR-alpha-2.A (zebrafish)" EXACT [UniProtKB:Q90271] synonym: "retinoic acid receptor alpha (zebrafish)" EXACT [UniProtKB:Q90271] synonym: "retinoic acid receptor alpha-2.A (zebrafish)" EXACT [UniProtKB:Q90271] synonym: "nuclear receptor subfamily 1 group B member 1-A (zebrafish)" EXACT [UniProtKB:Q90271] xref: UniProtKB:Q90271 intersection_of: only_in_taxon NCBITaxon:7955 ! Danio rerio intersection_of: PR:000013736 ! retinoic acid receptor alpha relationship: has_gene_template ZFIN:ZDB-GENE-980526-284 ! raraa (zebrafish) [Term] id: PR:P10276 name: retinoic acid receptor alpha (human) def: "A retinoic acid receptor alpha that is encoded in the genome of human." [PRO:DNx, UniProtKB:P10276] comment: Category=organism-gene. synonym: "RARA" RELATED Gene-based [UniProtKB:P10276] synonym: "NR1B1" RELATED Gene-based [UniProtKB:P10276] synonym: "hRARA" EXACT PRO-short-label [PRO:DNx] synonym: "RAR-alpha (human)" EXACT [UniProtKB:P10276] synonym: "nuclear receptor subfamily 1 group B member 1 (human)" EXACT [UniProtKB:P10276] xref: Reactome:R-HSA-446164 "PR:P10276 located_in GO:0005654" xref: DTO:00117482 xref: UniProtKB:P10276 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000013736 ! retinoic acid receptor alpha relationship: has_gene_template HGNC:9864 ! RARA (human) [Term] id: PR:000045664 name: retinoic acid receptor alpha phosphorylated 1 (human) def: "A retinoic acid receptor alpha (human) that has been phosphorylated on the residue at the position equivalent to Ser-77 of the amino acid sequence represented by UniProtKB:P10276-1. Example: UniProtKB:P10276-1, Ser-77, MOD:00046." [PMID:11955452, PMID:12054865, iPTMnet:P10276] comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:11955452, PMID:12054865). Status=unreviewed. synonym: "hRARA/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P10276-1, Ser-77, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P10276 ! retinoic acid receptor alpha (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000026078 name: retinoic acid receptor alpha isoform 1 phosphorylated 1 (human) def: "A retinoic acid receptor alpha isoform 1 phosphorylated 1 in human. UniProtKB:P10276-1, Ser-77, MOD:00046." [PMID:16275922, PRO:CNA, PRO:DAN] comment: Category=organism-modification. synonym: "hRARA/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P10276-1, Ser-77, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000026076 ! retinoic acid receptor alpha isoform 1 phosphorylated 1 relationship: has_part MOD:00046 ! O-phospho-L-serine [Term] id: PR:000022010 name: retinoic acid receptor alpha isoform 2 def: "A retinoic acid receptor alpha that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P11416-2 or a 1:1 ortholog thereof. This isoform lacks the N-terminal region that is known to be important for trans-activation by other members of the nuclear receptor superfamily." [PMID:1846598, PRO:HJD] comment: Category=sequence. synonym: "RARA/iso:2" EXACT PRO-short-label [PRO:DNx] synonym: "retinoic acid receptor isoform alpha-2" EXACT [] is_a: PR:000013736 ! retinoic acid receptor alpha