[Term]
id: PR:000049022
name: DNA endonuclease RBBP8 phosphorylated 1 (human)
def: "A DNA endonuclease RBBP8 (human) that has been phosphorylated on the residue at the position equivalent to Ser-327, and phosphothreonine at position 847 of the amino acid sequence represented by UniProtKB:Q99708. UniProtKB:Q99708, Ser-327, MOD:00046|Thr-847, MOD:00047." [PRO:DNx, Reactome:R-HSA-5684083]
comment: Category=organism-modification.
synonym: "hRBBP8/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q99708, Ser-327, MOD:00046|Thr-847, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5684083 "PR:000049022 located_in GO:0005654"
is_a: PR:Q99708 ! DNA endonuclease RBBP8 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000013780
name: DNA endonuclease RBBP8
def: "A protein that is a translation product of the human RBBP8 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "RIM" EXACT []
synonym: "CTIP" RELATED Gene-based []
synonym: "CtIP" EXACT []
synonym: "SAE2" EXACT []
synonym: "RBBP8" EXACT PRO-short-label [PRO:DNx]
synonym: "RBBP-8" EXACT []
synonym: "CtBP-interacting protein" EXACT []
synonym: "retinoblastoma-binding protein 8" EXACT []
synonym: "retinoblastoma-interacting protein and myosin-like" EXACT []
synonym: "sporulation in the absence of SPO11 protein 2 homolog" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000049021
name: DNA endonuclease RBBP8 acetylated 1 (human)
def: "A DNA endonuclease RBBP8 (human) that has been post-translationally modified to include N6-acetyllysine at positions 432, 526 and 604 of the amino acid sequence represented by UniProtKB:Q99708. UniProtKB:Q99708, Lys-432/Lys-526/Lys-604, MOD:00064." [PRO:DNx, Reactome:R-HSA-5685955]
comment: Category=organism-modification.
synonym: "hRBBP8/Ac:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q99708, Lys-432/Lys-526/Lys-604, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5685955 "PR:000049021 located_in GO:0005654"
is_a: PR:Q99708 ! DNA endonuclease RBBP8 (human)
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000049023
name: DNA endonuclease RBBP8 phosphorylated 2 (human)
def: "A DNA endonuclease RBBP8 (human) that has been phosphorylated on the residue at the position equivalent to Ser-327, and phosphothreonine at positions 847 and 859 of the amino acid sequence represented by UniProtKB:Q99708. UniProtKB:Q99708, Ser-327, MOD:00046|Thr-847/Thr-859, MOD:00047." [PRO:DNx, Reactome:R-HSA-5684138]
comment: Category=organism-modification.
synonym: "hRBBP8/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q99708, Ser-327, MOD:00046|Thr-847/Thr-859, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5684138 "PR:000049023 located_in GO:0005654"
is_a: PR:Q99708 ! DNA endonuclease RBBP8 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q99708
name: DNA endonuclease RBBP8 (human)
def: "A DNA endonuclease RBBP8 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q99708]
comment: Category=organism-gene.
synonym: "CTIP" RELATED Gene-based [UniProtKB:Q99708]
synonym: "RBBP8" RELATED Gene-based [UniProtKB:Q99708]
synonym: "hRBBP8" EXACT PRO-short-label [PRO:DNx]
synonym: "RIM (human)" EXACT [UniProtKB:Q99708]
synonym: "SAE2 (human)" EXACT [UniProtKB:Q99708]
synonym: "RBBP-8 (human)" EXACT [UniProtKB:Q99708]
synonym: "CtBP-interacting protein (human)" EXACT [UniProtKB:Q99708]
synonym: "retinoblastoma-binding protein 8 (human)" EXACT [UniProtKB:Q99708]
synonym: "retinoblastoma-interacting protein and myosin-like (human)" EXACT [UniProtKB:Q99708]
synonym: "sporulation in the absence of SPO11 protein 2 homolog (human)" EXACT [UniProtKB:Q99708]
xref: Reactome:R-HSA-912399 "PR:Q99708 located_in GO:0005654"
xref: UniProtKB:Q99708
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000013780 ! DNA endonuclease RBBP8
relationship: has_gene_template HGNC:9891 ! RBBP8 (human)

[Term]
id: PR:Q99708-2
name: DNA endonuclease RBBP8 isoform h2 (human)
def: "A DNA endonuclease RBBP8 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99708-2." [PRO:DNx, UniProtKB:Q99708]
comment: Category=organism-sequence.
synonym: "hRBBP8/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q99708-2
is_a: PR:Q99708 ! DNA endonuclease RBBP8 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q99708-3
name: DNA endonuclease RBBP8 isoform h3 (human)
def: "A DNA endonuclease RBBP8 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99708-3." [PRO:DNx, UniProtKB:Q99708]
comment: Category=organism-sequence.
synonym: "hRBBP8/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q99708-3
is_a: PR:Q99708 ! DNA endonuclease RBBP8 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q99708-1
name: DNA endonuclease RBBP8 isoform h1 (human)
def: "A DNA endonuclease RBBP8 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99708-1." [PRO:DNx, UniProtKB:Q99708]
comment: Category=organism-sequence.
synonym: "hRBBP8/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q99708-1
is_a: PR:Q99708 ! DNA endonuclease RBBP8 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens