[Term] id: PR:000049139 name: R-spondin-1, signal peptide removed form (human) def: "An R-spondin-1 (human) that has had the signal peptide removed. UniProtKB:Q2MKA7, 21-263." [PRO:DNx, Reactome:R-HSA-4641194] comment: Category=organism-modification. synonym: "PRO_0000234436" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hRSPO1/SigPep-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q2MKA7, 21-263" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-4641194 "PR:000049139 located_in GO:0005576" intersection_of: PR:Q2MKA7 ! R-spondin-1 (human) intersection_of: lacks_part SO:0000418 ! signal_peptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000014330 name: R-spondin-1 def: "A protein that is a translation product of the human RSPO1 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "RSPO1" EXACT PRO-short-label [PRO:DNx] synonym: "Rspo1" EXACT [] synonym: "Cristin-3" EXACT [] synonym: "cristin-3" EXACT [] synonym: "roof plate-specific spondin-1" EXACT [] synonym: "cysteine-rich and single thrombospondin domain-containing protein 3" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:Q2MKA7-1 name: R-spondin-1 isoform h1 (human) def: "An R-spondin-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q2MKA7-1." [PRO:DNx, UniProtKB:Q2MKA7] comment: Category=organism-sequence. synonym: "hRSPO1/iso:h1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q2MKA7-1 is_a: PR:Q2MKA7 ! R-spondin-1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q2MKA7-3 name: R-spondin-1 isoform h3 (human) def: "An R-spondin-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q2MKA7-3." [PRO:DNx, UniProtKB:Q2MKA7] comment: Category=organism-sequence. synonym: "hRSPO1/iso:h3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q2MKA7-3 is_a: PR:Q2MKA7 ! R-spondin-1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q2MKA7-2 name: R-spondin-1 isoform h2 (human) def: "An R-spondin-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q2MKA7-2." [PRO:DNx, UniProtKB:Q2MKA7] comment: Category=organism-sequence. synonym: "hRSPO1/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q2MKA7-2 is_a: PR:Q2MKA7 ! R-spondin-1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q2MKA7 name: R-spondin-1 (human) def: "An R-spondin-1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q2MKA7] comment: Category=organism-gene. synonym: "RSPO1" RELATED Gene-based [UniProtKB:Q2MKA7] synonym: "hRSPO1" EXACT PRO-short-label [PRO:DNx] synonym: "hRspo1" EXACT [UniProtKB:Q2MKA7] synonym: "roof plate-specific spondin-1 (human)" EXACT [UniProtKB:Q2MKA7] xref: UniProtKB:Q2MKA7 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000014330 ! R-spondin-1 relationship: has_gene_template HGNC:21679 ! RSPO1 (human)