[Term] id: PR:Q01196-10 name: runt-related transcription factor 1 isoform hAML-1I (human) def: "A runt-related transcription factor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q01196-10." [PRO:DNx, UniProtKB:Q01196] comment: Category=organism-sequence. synonym: "hRUNX1/iso:hAML-1I" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q01196-10 is_a: PR:Q01196 ! runt-related transcription factor 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q01196-11 name: runt-related transcription factor 1 isoform hAML-1L (human) def: "A runt-related transcription factor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q01196-11." [PRO:DNx, UniProtKB:Q01196] comment: Category=organism-sequence. synonym: "hRUNX1/iso:hAML-1L" EXACT PRO-short-label [PRO:DNx] synonym: "runt-related transcription factor 1 isoform AML1-delta N (human)" EXACT [UniProtKB:Q01196] xref: UniProtKB:Q01196-11 is_a: PR:Q01196 ! runt-related transcription factor 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q01196 name: runt-related transcription factor 1 (human) def: "A runt-related transcription factor 1 that is encoded in the genome of human." [PRO:PD] comment: Category=organism-gene. synonym: "AML1" RELATED Gene-based [UniProtKB:Q01196] synonym: "CBFA2" RELATED Gene-based [UniProtKB:Q01196] synonym: "RUNX1" RELATED Gene-based [UniProtKB:Q01196] synonym: "hRUNX1" EXACT PRO-short-label [PRO:DNx] synonym: "CBF-alpha-2 (human)" EXACT [UniProtKB:Q01196] synonym: "PEA2-alpha B (human)" EXACT [UniProtKB:Q01196] synonym: "PEBP2-alpha B (human)" EXACT [UniProtKB:Q01196] synonym: "oncogene AML-1 (human)" EXACT [UniProtKB:Q01196] synonym: "acute myeloid leukemia 1 protein (human)" EXACT [UniProtKB:Q01196] synonym: "core-binding factor subunit alpha-2 (human)" EXACT [UniProtKB:Q01196] synonym: "SL3-3 enhancer factor 1 alpha B subunit (human)" EXACT [UniProtKB:Q01196] synonym: "SL3/AKV core-binding factor alpha B subunit (human)" EXACT [UniProtKB:Q01196] synonym: "polyomavirus enhancer-binding protein 2 alpha B subunit (human)" EXACT [UniProtKB:Q01196] xref: Reactome:R-HSA-5667138 "PR:Q01196 located_in GO:0005886" xref: Reactome:R-HSA-8865295 "PR:Q01196 located_in GO:0005654" xref: UniProtKB:Q01196 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000014362 ! runt-related transcription factor 1 relationship: has_gene_template HGNC:10471 ! RUNX1 (human) [Term] id: PR:000014362 name: runt-related transcription factor 1 def: "A protein that is a translation product of the human RUNX1 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. Requested by=CL. synonym: "AML1" RELATED Gene-based [] synonym: "CBFA2" RELATED Gene-based [] synonym: "RUNX1" EXACT PRO-short-label [PRO:DNx] synonym: "Pebp2ab" RELATED Gene-based [] synonym: "CBF-alpha-2" EXACT [] synonym: "PEA2-alpha B" EXACT [] synonym: "PEBP2-alpha B" EXACT [] synonym: "oncogene AML-1" EXACT [] synonym: "acute myeloid leukemia 1 protein" EXACT [] synonym: "core-binding factor subunit alpha-2" EXACT [] synonym: "SL3-3 enhancer factor 1 alpha B subunit" EXACT [] synonym: "SL3/AKV core-binding factor alpha B subunit" EXACT [] synonym: "polyomavirus enhancer-binding protein 2 alpha B subunit" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:Q01196-8 name: runt-related transcription factor 1 isoform hAML-1G (human) def: "A runt-related transcription factor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q01196-8." [PRO:DNx, UniProtKB:Q01196] comment: Category=organism-sequence. synonym: "hRUNX1/iso:hAML-1G" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q01196-8 is_a: PR:Q01196 ! runt-related transcription factor 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q01196-9 name: runt-related transcription factor 1 isoform hAML-1H (human) def: "A runt-related transcription factor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q01196-9." [PRO:DNx, UniProtKB:Q01196] comment: Category=organism-sequence. synonym: "hRUNX1/iso:hAML-1H" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q01196-9 is_a: PR:Q01196 ! runt-related transcription factor 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000028561 name: runt-related transcription factor 1 acetylated 1 (human) def: "A runt-related transcription factor 1 acetylated 1 in human. Example: UniProtKB:Q01196-1, Lys-24/Lys-43, MOD:00064." [KAT:Q01196, PMID:14752096, PRO:PD] comment: Category=organism-modification. Acetylase=("EP300"; PR:000007102). synonym: "hRUNX1/Ac:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q01196-1, Lys-24/Lys-43, MOD:00064" NARROW PRO-proteoform-std [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000028560 ! runt-related transcription factor 1 acetylated 1 relationship: has_part MOD:00064 ! N6-acetyl-L-lysine [Term] id: PR:Q01196-1 name: runt-related transcription factor 1 isoform 1 (human) def: "A runt-related transcription factor 1 isoform 1 that is encoded in the genome of human." [PRO:AAA, UniProtKB:Q01196-1] comment: Category=organism-sequence. synonym: "hRUNX1/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q01196-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000028558 ! runt-related transcription factor 1 isoform 1 [Term] id: PR:Q01196-2 name: runt-related transcription factor 1 isoform 2 (human) def: "A runt-related transcription factor 1 isoform 2 that is encoded in the genome of human." [PRO:AAA, UniProtKB:Q01196-2] comment: Category=organism-sequence. synonym: "hRUNX1/iso:2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q01196-2 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000035626 ! runt-related transcription factor 1 isoform 2 [Term] id: PR:Q01196-3 name: runt-related transcription factor 1 isoform 3 (human) def: "A runt-related transcription factor 1 isoform 3 that is encoded in the genome of human." [PRO:AAA, UniProtKB:Q01196-3] comment: Category=organism-sequence. synonym: "hRUNX1/iso:3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q01196-3 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000035624 ! runt-related transcription factor 1 isoform 3 [Term] id: PR:Q01196-4 name: runt-related transcription factor 1 isoform hAML-1E (human) def: "A runt-related transcription factor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q01196-4." [PRO:DNx, UniProtKB:Q01196] comment: Category=organism-sequence. synonym: "hRUNX1/iso:hAML-1E" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q01196-4 is_a: PR:Q01196 ! runt-related transcription factor 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q01196-5 name: runt-related transcription factor 1 isoform hAML-1FA (human) def: "A runt-related transcription factor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q01196-5." [PRO:DNx, UniProtKB:Q01196] comment: Category=organism-sequence. synonym: "hRUNX1/iso:hAML-1FA" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q01196-5 is_a: PR:Q01196 ! runt-related transcription factor 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q01196-6 name: runt-related transcription factor 1 isoform hAML-1FB (human) def: "A runt-related transcription factor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q01196-6." [PRO:DNx, UniProtKB:Q01196] comment: Category=organism-sequence. synonym: "hRUNX1/iso:hAML-1FB" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q01196-6 is_a: PR:Q01196 ! runt-related transcription factor 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q01196-7 name: runt-related transcription factor 1 isoform hAML-1FC (human) def: "A runt-related transcription factor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q01196-7." [PRO:DNx, UniProtKB:Q01196] comment: Category=organism-sequence. synonym: "hRUNX1/iso:hAML-1FC" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q01196-7 is_a: PR:Q01196 ! runt-related transcription factor 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens