[Term]
id: PR:000014378
name: ryanodine receptor 2
def: "A ryanodine receptor that is a translation product of the human RYR2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "RYR2" EXACT PRO-short-label [PRO:DNx]
synonym: "RyR2" EXACT []
synonym: "RYR-2" EXACT []
synonym: "type 2 ryanodine receptor" EXACT []
synonym: "cardiac muscle ryanodine receptor" EXACT []
synonym: "cardiac muscle-type ryanodine receptor" EXACT []
synonym: "cardiac muscle ryanodine receptor-calcium release channel" EXACT []
xref: IUPHARobj:748
is_a: PR:000044656 ! ryanodine receptor

[Term]
id: PR:E9Q401
name: ryanodine receptor 2 (mouse)
def: "A ryanodine receptor 2 that is encoded in the genome of mouse." [OMA:E9Q401, PRO:DNx]
comment: Category=organism-gene.
synonym: "Ryr2" RELATED Gene-based [UniProtKB:E9Q401]
synonym: "mRYR2" EXACT PRO-short-label [PRO:DNx]
synonym: "RyR2 (mouse)" EXACT [UniProtKB:E9Q401]
synonym: "RYR-2 (mouse)" EXACT [UniProtKB:E9Q401]
synonym: "type 2 ryanodine receptor (mouse)" EXACT [UniProtKB:E9Q401]
synonym: "cardiac muscle ryanodine receptor (mouse)" EXACT [UniProtKB:E9Q401]
synonym: "cardiac muscle ryanodine receptor-calcium release channel (mouse)" EXACT [UniProtKB:E9Q401]
xref: UniProtKB:E9Q401
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000014378 ! ryanodine receptor 2
relationship: has_gene_template MGI:99685 ! Ryr2 (mouse)

[Term]
id: PR:000046012
name: ryanodine receptor 2 phosphorylated 1 (human)
def: "A ryanodine receptor 2 (human) that has been phosphorylated on the residue at the position equivalent to Ser-2814 of the amino acid sequence represented by UniProtKB:Q92736-1. Example: UniProtKB:Q92736-1, Ser-2814, MOD:00046." [PMID:22511749, iPTMnet:Q92736]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:22511749). Status=unreviewed.
synonym: "hRYR2/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q92736-1, Ser-2814, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q92736 ! ryanodine receptor 2 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q92736
name: ryanodine receptor 2 (human)
def: "A ryanodine receptor 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q92736]
comment: Category=organism-gene.
synonym: "RYR2" RELATED Gene-based [UniProtKB:Q92736]
synonym: "hRYR2" EXACT PRO-short-label [PRO:DNx]
synonym: "hRYR-2" EXACT [UniProtKB:Q92736]
synonym: "RyR2 (human)" EXACT [UniProtKB:Q92736]
synonym: "RYR-2 (human)" EXACT [UniProtKB:Q92736]
synonym: "type 2 ryanodine receptor (human)" EXACT [UniProtKB:Q92736]
synonym: "cardiac muscle ryanodine receptor (human)" EXACT [UniProtKB:Q92736]
synonym: "cardiac muscle ryanodine receptor-calcium release channel (human)" EXACT [UniProtKB:Q92736]
xref: Reactome:R-HSA-937283 "PR:Q92736 located_in GO:0033017"
xref: DTO:01100285
xref: UniProtKB:Q92736
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000014378 ! ryanodine receptor 2
relationship: has_gene_template HGNC:10484 ! RYR2 (human)

[Term]
id: PR:Q92736-1
name: ryanodine receptor 2 isoform h1 (human)
def: "A ryanodine receptor 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q92736-1." [PRO:DNx, UniProtKB:Q92736]
comment: Category=organism-sequence.
synonym: "hRYR2/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q92736-1
is_a: PR:Q92736 ! ryanodine receptor 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q92736-2
name: ryanodine receptor 2 isoform h2 (human)
def: "A ryanodine receptor 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q92736-2." [PRO:DNx, UniProtKB:Q92736]
comment: Category=organism-sequence.
synonym: "hRYR2/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q92736-2
is_a: PR:Q92736 ! ryanodine receptor 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens