[Term]
id: PR:000015189
name: sodium-dependent serotonin transporter
def: "A protein that is a translation product of the human SLC6A4 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "HTT" RELATED Gene-based []
synonym: "5HTT" EXACT []
synonym: "SERT" RELATED Gene-based []
synonym: "SLC6A4" EXACT PRO-short-label [PRO:DNx]
synonym: "5HT transporter" EXACT []
synonym: "solute carrier family 6 member 4" EXACT []
xref: IUPHARobj:928
is_a: PR:000000001 ! protein

[Term]
id: PR:P31645-2
name: sodium-dependent serotonin transporter isoform h2 (human)
def: "A sodium-dependent serotonin transporter (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P31645-2." [PRO:DNx, UniProtKB:P31645]
comment: Category=organism-sequence.
synonym: "hSLC6A4/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P31645-2
is_a: PR:P31645 ! sodium-dependent serotonin transporter (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045751
name: sodium-dependent serotonin transporter phosphorylated 1 (human)
def: "A sodium-dependent serotonin transporter (human) that has been phosphorylated on the residue at the position equivalent to Thr-276 of the amino acid sequence represented by UniProtKB:P31645-1. Example: UniProtKB:P31645-1, Thr-276, MOD:00047." [PMID:17913921, iPTMnet:P31645]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:17913921). Status=unreviewed.
synonym: "hSLC6A4/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P31645-1, Thr-276, MOD:00047" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P31645 ! sodium-dependent serotonin transporter (human)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P31645-1
name: sodium-dependent serotonin transporter isoform 1 (human)
def: "A sodium-dependent serotonin transporter (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P31645-1." [PRO:DNx, UniProtKB:P31645]
comment: Category=organism-sequence. Requested by=PubChem.
synonym: "hSLC6A4/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P31645-1
is_a: PR:P31645 ! sodium-dependent serotonin transporter (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P31645
name: sodium-dependent serotonin transporter (human)
def: "A sodium-dependent serotonin transporter that is encoded in the genome of human." [PRO:DNx, UniProtKB:P31645]
comment: Category=organism-gene.
synonym: "HTT" RELATED Gene-based [UniProtKB:P31645]
synonym: "SERT" RELATED Gene-based [UniProtKB:P31645]
synonym: "SLC6A4" RELATED Gene-based [UniProtKB:P31645]
synonym: "hSLC6A4" EXACT PRO-short-label [PRO:DNx]
synonym: "5HTT (human)" EXACT [UniProtKB:P31645]
synonym: "5HT transporter (human)" EXACT [UniProtKB:P31645]
synonym: "solute carrier family 6 member 4 (human)" EXACT [UniProtKB:P31645]
xref: Reactome:R-HSA-444015 "PR:P31645 located_in GO:0005886"
xref: UniProtKB:P31645
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000015189 ! sodium-dependent serotonin transporter
relationship: has_gene_template HGNC:11050 ! SLC6A4 (human)