[Term] id: PR:000021656 name: thyroglobulin, signal peptide removed form def: "A thyroglobulin that has had the signal peptide removed." [PRO:DNx] comment: Category=modification. synonym: "TG/SigPep-" EXACT PRO-short-label [PRO:DNx] intersection_of: PR:000016283 ! thyroglobulin intersection_of: lacks_part SO:0000418 ! signal_peptide [Term] id: PR:000016283 name: thyroglobulin def: "A protein that is a translation product of the human TG gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "TG" EXACT PRO-short-label [PRO:DNx] synonym: "Tg" EXACT [] synonym: "Tgn" RELATED Gene-based [] is_a: PR:000000001 ! protein [Term] id: PR:O08710-1 name: thyroglobulin isoform 1 (mouse) def: "A thyroglobulin (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O08710-1." [PMID:9344706, PRO:HJD] comment: Category=organism-sequence. synonym: "mTG/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:O08710-1 is_a: PR:O08710 ! thyroglobulin (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P01266 name: thyroglobulin (human) def: "A thyroglobulin that is encoded in the genome of human." [PRO:DNx, UniProtKB:P01266] comment: Category=organism-gene. synonym: "TG" RELATED Gene-based [UniProtKB:P01266] synonym: "hTG" EXACT PRO-short-label [PRO:DNx] synonym: "Tg (human)" EXACT [UniProtKB:P01266] xref: UniProtKB:P01266 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000016283 ! thyroglobulin relationship: has_gene_template HGNC:11764 ! TG (human) [Term] id: PR:P01266-1 name: thyroglobulin isoform h1 (human) def: "A thyroglobulin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P01266-1." [PRO:DNx, UniProtKB:P01266] comment: Category=organism-sequence. synonym: "hTG/iso:h1" EXACT PRO-short-label [PRO:DNx] synonym: "thyroglobulin isoform Major (human)" EXACT [UniProtKB:P01266] xref: UniProtKB:P01266-1 is_a: PR:P01266 ! thyroglobulin (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P01266-2 name: thyroglobulin isoform h2 (human) def: "A thyroglobulin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P01266-2." [PRO:DNx, UniProtKB:P01266] comment: Category=organism-sequence. synonym: "hTG/iso:h2" EXACT PRO-short-label [PRO:DNx] synonym: "thyroglobulin isoform Minor (human)" EXACT [UniProtKB:P01266] xref: UniProtKB:P01266-2 is_a: PR:P01266 ! thyroglobulin (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:O08710 name: thyroglobulin (mouse) def: "A thyroglobulin that is encoded in the genome of mouse." [OMA:O08710, PRO:DNx] comment: Category=organism-gene. synonym: "Tg" RELATED Gene-based [UniProtKB:O08710] synonym: "Tgn" RELATED Gene-based [UniProtKB:O08710] synonym: "mTG" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:O08710 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000016283 ! thyroglobulin relationship: has_gene_template MGI:98733 ! Tg (mouse) [Term] id: PR:A6P7M8 name: thyroglobulin isoform 2 (mouse) def: "A thyroglobulin (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:A6P7M8." [PMID:19716808, PRO:HJD] comment: Category=organism-sequence. Note: Exclusively expressed in kidney. Transcript starts in exon 41 of thyroglobulin gene and continues in frame to the normal stop codon. Confirmed at transcript and protein level. synonym: "mTG/iso:2" EXACT PRO-short-label [PRO:DNx] synonym: "kTg (mouse)" EXACT [] synonym: "kidney Tg (mouse)" EXACT [] xref: UniProtKB:A6P7M8 is_a: PR:O08710 ! thyroglobulin (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P06882 name: thyroglobulin (rat) def: "A thyroglobulin that is encoded in the genome of rat." [PANTHER:PTHR11559:SF31, PRO:DNx] comment: Category=organism-gene. synonym: "Tg" RELATED Gene-based [UniProtKB:P06882] synonym: "rTG" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P06882 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000016283 ! thyroglobulin relationship: has_gene_template RGD:3848 ! Tg (rat)