[Term]
id: PR:P07101
name: tyrosine 3-monooxygenase (human)
def: "A tyrosine 3-monooxygenase that is encoded in the genome of human." [PRO:DNx, UniProtKB:P07101]
comment: Category=organism-gene.
synonym: "TH" RELATED Gene-based [UniProtKB:P07101]
synonym: "TYH" RELATED Gene-based [UniProtKB:P07101]
synonym: "hTH" EXACT PRO-short-label [PRO:DNx]
synonym: "tyrosine 3-hydroxylase (human)" EXACT [UniProtKB:P07101]
xref: UniProtKB:P07101
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000016301 ! tyrosine 3-monooxygenase
relationship: has_gene_template HGNC:11782 ! TH (human)

[Term]
id: PR:P07101-1
name: tyrosine 3-monooxygenase isoform h3 (human)
def: "A tyrosine 3-monooxygenase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P07101-1." [PRO:DNx, UniProtKB:P07101]
comment: Category=organism-sequence.
synonym: "hTH/iso:h3" EXACT PRO-short-label [PRO:DNx]
synonym: "tyrosine 3-monooxygenase isoform TH type 4 (human)" EXACT [UniProtKB:P07101]
xref: UniProtKB:P07101-1
is_a: PR:P07101 ! tyrosine 3-monooxygenase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P07101-3
name: tyrosine 3-monooxygenase isoform h2 (human)
def: "A tyrosine 3-monooxygenase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P07101-3." [PRO:DNx, UniProtKB:P07101]
comment: Category=organism-sequence.
synonym: "hTH/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "tyrosine 3-monooxygenase isoform HTH-1 (human)" EXACT [UniProtKB:P07101]
synonym: "tyrosine 3-monooxygenase isoform TH type 1 (human)" EXACT [UniProtKB:P07101]
synonym: "tyrosine 3-monooxygenase isoform hTH-Delta1b,2 (human)" EXACT [UniProtKB:P07101]
xref: UniProtKB:P07101-3
is_a: PR:P07101 ! tyrosine 3-monooxygenase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P07101-2
name: tyrosine 3-monooxygenase isoform h1 (human)
def: "A tyrosine 3-monooxygenase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P07101-2." [PRO:DNx, UniProtKB:P07101]
comment: Category=organism-sequence.
synonym: "hTH/iso:h1" EXACT PRO-short-label [PRO:DNx]
synonym: "tyrosine 3-monooxygenase isoform TH type 3 (human)" EXACT [UniProtKB:P07101]
xref: UniProtKB:P07101-2
is_a: PR:P07101 ! tyrosine 3-monooxygenase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P07101-5
name: tyrosine 3-monooxygenase isoform h5 (human)
def: "A tyrosine 3-monooxygenase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P07101-5." [PRO:DNx, UniProtKB:P07101]
comment: Category=organism-sequence.
synonym: "hTH/iso:h5" EXACT PRO-short-label [PRO:DNx]
synonym: "tyrosine 3-monooxygenase isoform hTH-Delta2,8,9 (human)" EXACT [UniProtKB:P07101]
xref: UniProtKB:P07101-5
is_a: PR:P07101 ! tyrosine 3-monooxygenase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P07101-4
name: tyrosine 3-monooxygenase isoform h4 (human)
def: "A tyrosine 3-monooxygenase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P07101-4." [PRO:DNx, UniProtKB:P07101]
comment: Category=organism-sequence.
synonym: "hTH/iso:h4" EXACT PRO-short-label [PRO:DNx]
synonym: "tyrosine 3-monooxygenase isoform TH type 2 (human)" EXACT [UniProtKB:P07101]
synonym: "tyrosine 3-monooxygenase isoform hTH-Delta2 (human)" EXACT [UniProtKB:P07101]
xref: UniProtKB:P07101-4
is_a: PR:P07101 ! tyrosine 3-monooxygenase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P07101-6
name: tyrosine 3-monooxygenase isoform h6 (human)
def: "A tyrosine 3-monooxygenase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P07101-6." [PRO:DNx, UniProtKB:P07101]
comment: Category=organism-sequence.
synonym: "hTH/iso:h6" EXACT PRO-short-label [PRO:DNx]
synonym: "tyrosine 3-monooxygenase isoform hTH-Delta1b,2,8,9 (human)" EXACT [UniProtKB:P07101]
xref: UniProtKB:P07101-6
is_a: PR:P07101 ! tyrosine 3-monooxygenase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000049436
name: tyrosine 3-monooxygenase, initiator methionine removed form (human)
def: "A tyrosine 3-monooxygenase (human) that has had the initiator methionine removed. UniProtKB:P07101, 2-528." [PRO:DNx, Reactome:R-HSA-2980863]
comment: Category=organism-modification.
synonym: "hTH/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000205561" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P07101, 2-528" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2980863 "PR:000049436 located_in GO:0005829"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:P07101 ! tyrosine 3-monooxygenase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000016301
name: tyrosine 3-monooxygenase
def: "A protein that is a translation product of the human TH gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "TH" EXACT PRO-short-label [PRO:DNx]
synonym: "TYH" RELATED Gene-based []
synonym: "tyrosine 3-hydroxylase" EXACT []
xref: IUPHARobj:1243
is_a: PR:000000001 ! protein