[Term] id: PR:000049452 name: Rho guanine nucleotide exchange factor TIAM2, initiator methionine removed form (human) def: "A Rho guanine nucleotide exchange factor TIAM2 (human) that has had the initiator methionine removed. UniProtKB:Q8IVF5, 2-1701." [PRO:DNx, Reactome:R-HSA-561165] comment: Category=organism-modification. synonym: "PRO_0000317467" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hTIAM2/InitMet-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q8IVF5, 2-1701" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-561165 "PR:000049452 located_in GO:0005829" intersection_of: lacks_part PR:000021937 ! initiator methionine intersection_of: PR:Q8IVF5 ! Rho guanine nucleotide exchange factor TIAM2 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q8IVF5 name: Rho guanine nucleotide exchange factor TIAM2 (human) def: "A Rho guanine nucleotide exchange factor TIAM2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q8IVF5] comment: Category=organism-gene. synonym: "STEF" RELATED Gene-based [UniProtKB:Q8IVF5] synonym: "TIAM2" RELATED Gene-based [UniProtKB:Q8IVF5] synonym: "hTIAM2" EXACT PRO-short-label [PRO:DNx] synonym: "KIAA2016" RELATED Gene-based [UniProtKB:Q8IVF5] synonym: "TIAM-2 (human)" EXACT [UniProtKB:Q8IVF5] synonym: "SIF and TIAM1-like exchange factor (human)" EXACT [UniProtKB:Q8IVF5] synonym: "T-lymphoma invasion and metastasis-inducing protein 2 (human)" EXACT [UniProtKB:Q8IVF5] xref: UniProtKB:Q8IVF5 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000016329 ! Rho guanine nucleotide exchange factor TIAM2 relationship: has_gene_template HGNC:11806 ! TIAM2 (human) [Term] id: PR:Q8IVF5-5 name: Rho guanine nucleotide exchange factor TIAM2 isoform h5 (human) def: "A Rho guanine nucleotide exchange factor TIAM2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IVF5-5." [PRO:DNx, UniProtKB:Q8IVF5] comment: Category=organism-sequence. synonym: "hTIAM2/iso:h5" EXACT PRO-short-label [PRO:DNx] synonym: "Rho guanine nucleotide exchange factor TIAM2 isoform Long (human)" EXACT [UniProtKB:Q8IVF5] xref: UniProtKB:Q8IVF5-5 is_a: PR:Q8IVF5 ! Rho guanine nucleotide exchange factor TIAM2 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q8IVF5-4 name: Rho guanine nucleotide exchange factor TIAM2 isoform h4 (human) def: "A Rho guanine nucleotide exchange factor TIAM2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IVF5-4." [PRO:DNx, UniProtKB:Q8IVF5] comment: Category=organism-sequence. synonym: "hTIAM2/iso:h4" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q8IVF5-4 is_a: PR:Q8IVF5 ! Rho guanine nucleotide exchange factor TIAM2 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000016329 name: Rho guanine nucleotide exchange factor TIAM2 def: "A protein that is a translation product of the human TIAM2 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "STEF" RELATED Gene-based [] synonym: "TIAM2" EXACT PRO-short-label [PRO:DNx] synonym: "TIAM-2" EXACT [] synonym: "KIAA2016" RELATED Gene-based [] synonym: "SIF and TIAM1-like exchange factor" EXACT [] synonym: "T-lymphoma invasion and metastasis-inducing protein 2" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:Q8IVF5-1 name: Rho guanine nucleotide exchange factor TIAM2 isoform h1 (human) def: "A Rho guanine nucleotide exchange factor TIAM2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IVF5-1." [PRO:DNx, UniProtKB:Q8IVF5] comment: Category=organism-sequence. synonym: "hTIAM2/iso:h1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q8IVF5-1 is_a: PR:Q8IVF5 ! Rho guanine nucleotide exchange factor TIAM2 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q8IVF5-3 name: Rho guanine nucleotide exchange factor TIAM2 isoform h3 (human) def: "A Rho guanine nucleotide exchange factor TIAM2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IVF5-3." [PRO:DNx, UniProtKB:Q8IVF5] comment: Category=organism-sequence. synonym: "hTIAM2/iso:h3" EXACT PRO-short-label [PRO:DNx] synonym: "Rho guanine nucleotide exchange factor TIAM2 isoform Short (human)" EXACT [UniProtKB:Q8IVF5] xref: UniProtKB:Q8IVF5-3 is_a: PR:Q8IVF5 ! Rho guanine nucleotide exchange factor TIAM2 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q8IVF5-2 name: Rho guanine nucleotide exchange factor TIAM2 isoform h2 (human) def: "A Rho guanine nucleotide exchange factor TIAM2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IVF5-2." [PRO:DNx, UniProtKB:Q8IVF5] comment: Category=organism-sequence. synonym: "hTIAM2/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q8IVF5-2 is_a: PR:Q8IVF5 ! Rho guanine nucleotide exchange factor TIAM2 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens