[Term]
id: PR:000016353
name: metalloproteinase inhibitor 2
def: "A protein that is a translation product of the human TIMP2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "TIMP2" EXACT PRO-short-label [PRO:DNx]
synonym: "TIMP-2" EXACT []
synonym: "CSC-21K" EXACT []
synonym: "tissue inhibitor of metalloproteinases 2" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:P16035
name: metalloproteinase inhibitor 2 (human)
def: "A metalloproteinase inhibitor 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P16035]
comment: Category=organism-gene.
synonym: "TIMP2" RELATED Gene-based [UniProtKB:P16035]
synonym: "hTIMP2" EXACT PRO-short-label [PRO:DNx]
synonym: "TIMP-2 (human)" EXACT [UniProtKB:P16035]
synonym: "CSC-21K (human)" EXACT [UniProtKB:P16035]
synonym: "tissue inhibitor of metalloproteinases 2 (human)" EXACT [UniProtKB:P16035]
xref: UniProtKB:P16035
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000016353 ! metalloproteinase inhibitor 2
relationship: has_gene_template HGNC:11821 ! TIMP2 (human)

[Term]
id: PR:000049458
name: metalloproteinase inhibitor 2, signal peptide removed form (human)
def: "A metalloproteinase inhibitor 2 (human) that has had the signal peptide removed. UniProtKB:P16035, 27-220." [PRO:DNx, Reactome:R-HSA-1454879]
comment: Category=organism-modification.
synonym: "PRO_0000034335" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hTIMP2/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P16035, 27-220" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-1454879 "PR:000049458 located_in GO:0005576"
xref: Reactome:R-HSA-6799625 "PR:000049458 located_in GO:0035580"
xref: Reactome:R-HSA-6800881 "PR:000049458 located_in GO:1904724"
xref: Reactome:R-HSA-6800944 "PR:000049458 located_in GO:1904813"
intersection_of: PR:P16035 ! metalloproteinase inhibitor 2 (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P16035-1
name: metalloproteinase inhibitor 2 isoform 1 (human)
def: "A metalloproteinase inhibitor 2 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hTIMP2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P16035-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000038944 ! metalloproteinase inhibitor 2 isoform 1