[Term]
id: PR:Q02880-1
name: DNA topoisomerase 2-beta isoform hBeta-2 (human)
def: "A DNA topoisomerase 2-beta (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q02880-1." [PRO:DNx, UniProtKB:Q02880]
comment: Category=organism-sequence.
synonym: "hTOP2B/iso:hBeta-2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q02880-1
is_a: PR:Q02880 ! DNA topoisomerase 2-beta (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000016545
name: DNA topoisomerase 2-beta
def: "A protein that is a translation product of the human TOP2B gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "TOP2B" EXACT PRO-short-label [PRO:DNx]
synonym: "DNA topoisomerase II, beta isozyme" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q02880
name: DNA topoisomerase 2-beta (human)
def: "A DNA topoisomerase 2-beta that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q02880]
comment: Category=organism-gene.
synonym: "TOP2B" RELATED Gene-based [UniProtKB:Q02880]
synonym: "hTOP2B" EXACT PRO-short-label [PRO:DNx]
synonym: "DNA topoisomerase II, beta isozyme (human)" EXACT [UniProtKB:Q02880]
xref: Reactome:R-HSA-4641359 "PR:Q02880 located_in GO:0005654"
xref: UniProtKB:Q02880
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000016545 ! DNA topoisomerase 2-beta
relationship: has_gene_template HGNC:11990 ! TOP2B (human)

[Term]
id: PR:000049510
name: DNA topoisomerase 2-beta sumoylated form (human)
def: "A DNA topoisomerase 2-beta (human) that includes at least one sumoylated lysine. UniProtKB:Q02880, MOD:01149." [PRO:DNx, Reactome:R-HSA-4641297]
comment: Category=organism-modification.
synonym: "hTOP2B/SumoLys+" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q02880, MOD:01149" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-4641297 "PR:000049510 located_in GO:0005654"
intersection_of: has_part MOD:01149 ! sumoylated lysine
intersection_of: PR:Q02880 ! DNA topoisomerase 2-beta (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q02880-2
name: DNA topoisomerase 2-beta isoform hBeta-1 (human)
def: "A DNA topoisomerase 2-beta (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q02880-2." [PRO:DNx, UniProtKB:Q02880]
comment: Category=organism-sequence.
synonym: "hTOP2B/iso:hBeta-1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q02880-2
is_a: PR:Q02880 ! DNA topoisomerase 2-beta (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens