[Term]
id: PR:Q9NS56-2
name: E3 ubiquitin-protein ligase Topors isoform h2 (human)
def: "An E3 ubiquitin-protein ligase Topors (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NS56-2." [PRO:DNx, UniProtKB:Q9NS56]
comment: Category=organism-sequence.
synonym: "hTOPORS/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "E3 ubiquitin-protein ligase Topors isoform LUN-2 (human)" EXACT [UniProtKB:Q9NS56]
xref: UniProtKB:Q9NS56-2
is_a: PR:Q9NS56 ! E3 ubiquitin-protein ligase Topors (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9NS56-1
name: E3 ubiquitin-protein ligase Topors isoform h1 (human)
def: "An E3 ubiquitin-protein ligase Topors (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NS56-1." [PRO:DNx, UniProtKB:Q9NS56]
comment: Category=organism-sequence.
synonym: "hTOPORS/iso:h1" EXACT PRO-short-label [PRO:DNx]
synonym: "E3 ubiquitin-protein ligase Topors isoform LUN-1 (human)" EXACT [UniProtKB:Q9NS56]
xref: UniProtKB:Q9NS56-1
is_a: PR:Q9NS56 ! E3 ubiquitin-protein ligase Topors (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q80Z37
name: E3 ubiquitin-protein ligase Topors (mouse)
def: "An E3 ubiquitin-protein ligase Topors that is encoded in the genome of mouse." [OMA:Q80Z37, PRO:DNx]
comment: Category=organism-gene.
synonym: "Topors" RELATED Gene-based [UniProtKB:Q80Z37]
synonym: "mTOPORS" EXACT PRO-short-label [PRO:DNx]
synonym: "p53BP3 (mouse)" EXACT [UniProtKB:Q80Z37]
synonym: "p53-binding protein 3 (mouse)" EXACT [UniProtKB:Q80Z37]
synonym: "SUMO1-protein E3 ligase Topors (mouse)" EXACT [UniProtKB:Q80Z37]
synonym: "tumor suppressor p53-binding protein 3 (mouse)" EXACT [UniProtKB:Q80Z37]
synonym: "RING-type E3 ubiquitin transferase Topors (mouse)" EXACT [UniProtKB:Q80Z37]
synonym: "topoisomerase I-binding RING finger protein (mouse)" EXACT [UniProtKB:Q80Z37]
synonym: "topoisomerase I-binding arginine/serine-rich protein (mouse)" EXACT [UniProtKB:Q80Z37]
xref: UniProtKB:Q80Z37
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000016549 ! E3 ubiquitin-protein ligase Topors
relationship: has_gene_template MGI:2146189 ! Topors (mouse)

[Term]
id: PR:Q54UA7
name: uncharacterized protein, DDB_G0281183 translation product (Dictyostelium discoideum)
def: "An E3 ubiquitin-protein ligase Topors that is encoded in the genome of Dictyostelium discoideum." [PANTHER:PTHR12456:SF8, PRO:DNx]
comment: Category=organism-gene.
synonym: "Dicty-TOPORS" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q54UA7
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000016549 ! E3 ubiquitin-protein ligase Topors
relationship: has_gene_template dictyBase:DDB_G0281183 ! DDB_G0281183 (Dictyostelium discoideum)

[Term]
id: PR:Q9NS56
name: E3 ubiquitin-protein ligase Topors (human)
def: "An E3 ubiquitin-protein ligase Topors that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9NS56]
comment: Category=organism-gene.
synonym: "LUN" RELATED Gene-based [UniProtKB:Q9NS56]
synonym: "TOPORS" RELATED Gene-based [UniProtKB:Q9NS56]
synonym: "TP53BPL" RELATED Gene-based [UniProtKB:Q9NS56]
synonym: "hTOPORS" EXACT PRO-short-label [PRO:DNx]
synonym: "p53BP3 (human)" EXACT [UniProtKB:Q9NS56]
synonym: "p53-binding protein 3 (human)" EXACT [UniProtKB:Q9NS56]
synonym: "SUMO1-protein E3 ligase Topors (human)" EXACT [UniProtKB:Q9NS56]
synonym: "tumor suppressor p53-binding protein 3 (human)" EXACT [UniProtKB:Q9NS56]
synonym: "RING-type E3 ubiquitin transferase Topors (human)" EXACT [UniProtKB:Q9NS56]
synonym: "topoisomerase I-binding RING finger protein (human)" EXACT [UniProtKB:Q9NS56]
synonym: "topoisomerase I-binding arginine/serine-rich protein (human)" EXACT [UniProtKB:Q9NS56]
xref: Reactome:R-HSA-2993791 "PR:Q9NS56 located_in GO:0005654"
xref: UniProtKB:Q9NS56
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000016549 ! E3 ubiquitin-protein ligase Topors
relationship: has_gene_template HGNC:21653 ! TOPORS (human)

[Term]
id: PR:Q9V8P9
name: E3 ubiquitin-protein ligase Topors (fruit fly)
def: "An E3 ubiquitin-protein ligase Topors that is encoded in the genome of fruit fly." [PANTHER:PTHR12456:SF8, PRO:DNx]
comment: Category=organism-gene.
synonym: "Topors" RELATED Gene-based [UniProtKB:Q9V8P9]
synonym: "CG15104" RELATED Gene-based [UniProtKB:Q9V8P9]
synonym: "dTopors" EXACT [UniProtKB:Q9V8P9]
synonym: "fly-TOPORS" EXACT PRO-short-label [PRO:DNx]
synonym: "SUMO1-protein E3 ligase Topors (fruit fly)" EXACT [UniProtKB:Q9V8P9]
synonym: "RING-type E3 ubiquitin transferase Topors (fruit fly)" EXACT [UniProtKB:Q9V8P9]
synonym: "topoisomerase I-binding RING finger protein (fruit fly)" EXACT [UniProtKB:Q9V8P9]
synonym: "topoisomerase I-binding arginine/serine-rich protein (fruit fly)" EXACT [UniProtKB:Q9V8P9]
xref: UniProtKB:Q9V8P9
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000016549 ! E3 ubiquitin-protein ligase Topors
relationship: has_gene_template FlyBase:FBgn0267351 ! Topors (fruit fly)

[Term]
id: PR:000016549
name: E3 ubiquitin-protein ligase Topors
def: "A protein that is a translation product of the human TOPORS gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "LUN" RELATED Gene-based []
synonym: "TOPORS" EXACT PRO-short-label [PRO:DNx]
synonym: "p53BP3" EXACT []
synonym: "TP53BPL" RELATED Gene-based []
synonym: "p53-binding protein 3" EXACT []
synonym: "SUMO1-protein E3 ligase Topors" EXACT []
synonym: "tumor suppressor p53-binding protein 3" EXACT []
synonym: "RING-type E3 ubiquitin transferase Topors" EXACT []
synonym: "topoisomerase I-binding RING finger protein" EXACT []
synonym: "topoisomerase I-binding arginine/serine-rich protein" EXACT []
is_a: PR:000000001 ! protein