[Term]
id: PR:P40818
name: ubiquitin carboxyl-terminal hydrolase 8 (human)
def: "A ubiquitin carboxyl-terminal hydrolase 8 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P40818]
comment: Category=organism-gene.
synonym: "UBPY" RELATED Gene-based [UniProtKB:P40818]
synonym: "USP8" RELATED Gene-based [UniProtKB:P40818]
synonym: "hUBPy" EXACT [UniProtKB:P40818]
synonym: "hUSP8" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA0055" RELATED Gene-based [UniProtKB:P40818]
synonym: "ubiquitin isopeptidase Y (human)" EXACT [UniProtKB:P40818]
synonym: "ubiquitin thioesterase 8 (human)" EXACT [UniProtKB:P40818]
synonym: "deubiquitinating enzyme 8 (human)" EXACT [UniProtKB:P40818]
synonym: "ubiquitin-specific-processing protease 8 (human)" EXACT [UniProtKB:P40818]
xref: Reactome:R-HSA-917720 "PR:P40818 located_in GO:0005829"
xref: UniProtKB:P40818
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000017197 ! ubiquitin carboxyl-terminal hydrolase 8
relationship: has_gene_template HGNC:12631 ! USP8 (human)

[Term]
id: PR:000049634
name: ubiquitin carboxyl-terminal hydrolase 8 phosphorylated 1 (human)
def: "A ubiquitin carboxyl-terminal hydrolase 8 (human) that has been phosphorylated on the residue at the position equivalent to Thr-945 of the amino acid sequence represented by UniProtKB:P40818. UniProtKB:P40818, Thr-945, MOD:00047." [PRO:DNx, Reactome:R-HSA-1358714]
comment: Category=organism-modification.
synonym: "hUSP8/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P40818, Thr-945, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-1358714 "PR:000049634 located_in GO:0005829"
is_a: PR:P40818 ! ubiquitin carboxyl-terminal hydrolase 8 (human)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000017197
name: ubiquitin carboxyl-terminal hydrolase 8
def: "A protein that is a translation product of the human USP8 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "UBPY" RELATED Gene-based []
synonym: "UBPy" EXACT []
synonym: "USP8" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA0055" RELATED Gene-based []
synonym: "ubiquitin isopeptidase Y" EXACT []
synonym: "ubiquitin thioesterase 8" EXACT []
synonym: "deubiquitinating enzyme 8" EXACT []
synonym: "ubiquitin-specific-processing protease 8" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:P40818-1
name: ubiquitin carboxyl-terminal hydrolase 8 isoform h1 (human)
def: "A ubiquitin carboxyl-terminal hydrolase 8 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P40818-1." [PRO:DNx, UniProtKB:P40818]
comment: Category=organism-sequence.
synonym: "hUSP8/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P40818-1
is_a: PR:P40818 ! ubiquitin carboxyl-terminal hydrolase 8 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P40818-2
name: ubiquitin carboxyl-terminal hydrolase 8 isoform h2 (human)
def: "A ubiquitin carboxyl-terminal hydrolase 8 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P40818-2." [PRO:DNx, UniProtKB:P40818]
comment: Category=organism-sequence.
synonym: "hUSP8/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P40818-2
is_a: PR:P40818 ! ubiquitin carboxyl-terminal hydrolase 8 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens