[Term]
id: PR:000042762
name: serine/threonine-protein kinase VRK1 isoform 1
def: "A serine/threonine-protein kinase VRK1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99986-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "VRK1/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000017349 ! serine/threonine-protein kinase VRK1

[Term]
id: PR:Q7KRY6
name: nucleosomal histone kinase 1 (fruit fly)
def: "A serine/threonine-protein kinase VRK1 that is encoded in the genome of fruit fly." [OMA:Q7KRY6, PRO:DNx]
comment: Category=organism-gene.
synonym: "ball" RELATED Gene-based [UniProtKB:Q7KRY6]
synonym: "nhk-1" RELATED Gene-based [UniProtKB:Q7KRY6]
synonym: "CG6386" RELATED Gene-based [UniProtKB:Q7KRY6]
synonym: "ballchen" RELATED Gene-based [UniProtKB:Q7KRY6]
synonym: "fly-VRK1" EXACT PRO-short-label [PRO:DNx]
synonym: "protein baellchen (fruit fly)" EXACT [UniProtKB:Q7KRY6]
xref: UniProtKB:Q7KRY6
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000017349 ! serine/threonine-protein kinase VRK1
relationship: has_gene_template FlyBase:FBgn0027889 ! ball (fruit fly)

[Term]
id: PR:Q80X41-2
name: serine/threonine-protein kinase VRK1 isoform 2 (mouse)
def: "A serine/threonine-protein kinase VRK1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mVRK1/iso:2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q80X41-2
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000042762 ! serine/threonine-protein kinase VRK1 isoform 1

[Term]
id: PR:Q80X41-3
name: serine/threonine-protein kinase VRK1 isoform m3 (mouse)
def: "A serine/threonine-protein kinase VRK1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q80X41-3." [PRO:DNx, UniProtKB:Q80X41]
comment: Category=organism-sequence.
synonym: "mVRK1/iso:m3" EXACT PRO-short-label [PRO:DNx]
synonym: "serine/threonine-protein kinase VRK1 isoform S (mouse)" EXACT [UniProtKB:Q80X41]
xref: UniProtKB:Q80X41-3
is_a: PR:Q80X41 ! serine/threonine-protein kinase VRK1 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q80X41-1
name: serine/threonine-protein kinase VRK1 isoform m1 (mouse)
def: "A serine/threonine-protein kinase VRK1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q80X41-1." [PRO:DNx, UniProtKB:Q80X41]
comment: Category=organism-sequence.
synonym: "mVRK1/iso:m1" EXACT PRO-short-label [PRO:DNx]
synonym: "serine/threonine-protein kinase VRK1 isoform L (mouse)" EXACT [UniProtKB:Q80X41]
xref: UniProtKB:Q80X41-1
is_a: PR:Q80X41 ! serine/threonine-protein kinase VRK1 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q80X41-5
name: serine/threonine-protein kinase VRK1 isoform m5 (mouse)
def: "A serine/threonine-protein kinase VRK1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q80X41-5." [PRO:DNx, UniProtKB:Q80X41]
comment: Category=organism-sequence.
synonym: "mVRK1/iso:m5" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q80X41-5
is_a: PR:Q80X41 ! serine/threonine-protein kinase VRK1 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q7ZUS1
name: serine/threonine-protein kinase VRK1 (zebrafish)
def: "A serine/threonine-protein kinase VRK1 that is encoded in the genome of zebrafish." [PRO:DNx]
comment: Category=organism-gene.
synonym: "vrk1" RELATED Gene-based [UniProtKB:Q7ZUS1]
synonym: "z-VRK1" EXACT PRO-short-label [PRO:DNx]
synonym: "zgc:56266" RELATED Gene-based [UniProtKB:Q7ZUS1]
synonym: "vaccinia-related kinase 1 (zebrafish)" EXACT [UniProtKB:Q7ZUS1]
xref: UniProtKB:Q7ZUS1
intersection_of: only_in_taxon NCBITaxon:7955 ! Danio rerio
intersection_of: PR:000017349 ! serine/threonine-protein kinase VRK1
relationship: has_gene_template ZFIN:ZDB-GENE-040426-2709 ! vrk1 (zebrafish)

[Term]
id: PR:Q99986-1
name: serine/threonine-protein kinase VRK1 isoform 1 (human)
def: "A serine/threonine-protein kinase VRK1 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hVRK1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q99986-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000042762 ! serine/threonine-protein kinase VRK1 isoform 1

[Term]
id: PR:000017349
name: serine/threonine-protein kinase VRK1
def: "A protein that is a translation product of the human VRK1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "VRK1" EXACT PRO-short-label [PRO:DNx]
synonym: "vaccinia-related kinase 1" EXACT []
synonym: "serine/threonine-protein kinase 51PK" EXACT []
xref: IUPHARobj:2275
is_a: PR:000000001 ! protein

[Term]
id: PR:Q80X41
name: serine/threonine-protein kinase VRK1 (mouse)
def: "A serine/threonine-protein kinase VRK1 that is encoded in the genome of mouse." [OMA:Q80X41, PRO:DNx]
comment: Category=organism-gene.
synonym: "Vrk1" RELATED Gene-based [UniProtKB:Q80X41]
synonym: "mVRK1" EXACT PRO-short-label [PRO:DNx]
synonym: "vaccinia-related kinase 1 (mouse)" EXACT [UniProtKB:Q80X41]
synonym: "serine/threonine-protein kinase 51PK (mouse)" EXACT [UniProtKB:Q80X41]
xref: UniProtKB:Q80X41
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000017349 ! serine/threonine-protein kinase VRK1
relationship: has_gene_template MGI:1261847 ! Vrk1 (mouse)

[Term]
id: PR:000046040
name: serine/threonine-protein kinase VRK1 phosphorylated 1 (human)
def: "A serine/threonine-protein kinase VRK1 (human) that has been phosphorylated at Ser-342. UniProtKB:Q99986, Ser-342, MOD:00046." [PMID:19103756, iPTMnet:Q99986]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:19103756). Status=unreviewed.
synonym: "hVRK1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q99986, Ser-342, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:Q99986 ! serine/threonine-protein kinase VRK1 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q99986
name: serine/threonine-protein kinase VRK1 (human)
def: "A serine/threonine-protein kinase VRK1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q99986]
comment: Category=organism-gene.
synonym: "VRK1" RELATED Gene-based [UniProtKB:Q99986]
synonym: "hVRK1" EXACT PRO-short-label [PRO:DNx]
synonym: "vaccinia-related kinase 1 (human)" EXACT [UniProtKB:Q99986]
xref: Reactome:R-HSA-2528998 "PR:Q99986 located_in GO:0005654"
xref: Reactome:R-HSA-2995381 "PR:Q99986 located_in GO:0005829"
xref: DTO:03100562
xref: UniProtKB:Q99986
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000017349 ! serine/threonine-protein kinase VRK1
relationship: has_gene_template HGNC:12718 ! VRK1 (human)