[Term]
id: PR:000045784
name: actin nucleation-promoting factor WAS, initiator methionine removed phosphorylated 1 (human)
def: "An actin nucleation-promoting factor WAS (human) that has had the initiator methionine removed and that has been phosphorylated on the residue at the position equivalent to Tyr-291 of the amino acid sequence represented by UniProtKB:P42768. UniProtKB:P42768, 2-502, Tyr-291, MOD:00048." [PMID:12235133, PMID:12769846, Reactome:R-HSA-2197668, iPTMnet:P42768]
comment: Category=organism-modification.
synonym: "hWAS/InitMet-/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P42768, 2-502, Tyr-291, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2197668 "PR:000045784 located_in GO:0005829"
is_a: PR:P42768 ! actin nucleation-promoting factor WAS (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:P42768
name: actin nucleation-promoting factor WAS (human)
def: "An actin nucleation-promoting factor WAS that is encoded in the genome of human." [PRO:DNx, UniProtKB:P42768]
comment: Category=organism-gene.
synonym: "WAS" RELATED Gene-based [UniProtKB:P42768]
synonym: "IMD2" RELATED Gene-based [UniProtKB:P42768]
synonym: "hWAS" EXACT PRO-short-label [PRO:DNx]
synonym: "WASp (human)" EXACT [UniProtKB:P42768]
synonym: "Wiskott-Aldrich syndrome protein (human)" EXACT [UniProtKB:P42768]
xref: UniProtKB:P42768
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000017371 ! actin nucleation-promoting factor WAS
relationship: has_gene_template HGNC:12731 ! WAS (human)

[Term]
id: PR:000049669
name: actin nucleation-promoting factor WAS, initiator methionine removed form (human)
def: "An actin nucleation-promoting factor WAS (human) that has had the initiator methionine removed. UniProtKB:P42768, 2-502." [PRO:DNx, Reactome:R-HSA-201879]
comment: Category=organism-modification.
synonym: "hWAS/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000188990" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P42768, 2-502" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-201879 "PR:000049669 located_in GO:0005829"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:P42768 ! actin nucleation-promoting factor WAS (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000017371
name: actin nucleation-promoting factor WAS
def: "A protein that is a translation product of the human WAS gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "WAS" EXACT PRO-short-label [PRO:DNx]
synonym: "IMD2" RELATED Gene-based []
synonym: "WASp" EXACT []
synonym: "Wiskott-Aldrich syndrome protein" EXACT []
is_a: PR:000000001 ! protein