[Term] id: PR:P83741-3 name: serine/threonine-protein kinase WNK1, dorsal root ganglia and sciatic nerve isoform (mouse) def: "A serine/threonine-protein kinase WNK1, dorsal root ganglia and sciatic nerve isoform that is encoded in the genome of mouse." [PMID:18521183, PRO:HJD] comment: Category=organism-sequence. synonym: "mWNK1/iso:drgsn" EXACT PRO-short-label [PRO:DAN] synonym: "WNK1 DRG and sciatic nerve variant (mouse)" EXACT [UniProtKB:P83741] synonym: "serine/threonine-protein kinase WNK1 isoform 3 (mouse)" EXACT [UniProtKB:P83741] synonym: "WNK1 dorsal root ganglia and sciatic nerve variant (mouse)" EXACT [UniProtKB:P83741] xref: UniProtKB:P83741-3 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000037201 ! serine/threonine-protein kinase WNK1, dorsal root ganglia and sciatic nerve isoform [Term] id: PR:P83741-2 name: serine/threonine-protein kinase WNK1, brain and spinal cord isoform (mouse) def: "A serine/threonine-protein kinase WNK1, brain and spinal cord isoform that is encoded in the genome of mouse." [PMID:18521183, PRO:HJD] comment: Category=organism-sequence. synonym: "mWNK1/iso:bsc" EXACT PRO-short-label [PRO:DAN] synonym: "WNK1 brain and spinal cord variant (mouse)" RELATED [] synonym: "serine/threonine-protein kinase WNK1 isoform 2 (mouse)" EXACT [UniProtKB:P83741] xref: UniProtKB:P83741-2 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000037199 ! serine/threonine-protein kinase WNK1, brain and spinal cord isoform [Term] id: PR:P83741-1 name: serine/threonine-protein kinase WNK1 isoform m1 (mouse) def: "A serine/threonine-protein kinase WNK1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P83741-1." [PMID:14514722, PRO:DAN, PRO:HJD] comment: Category=organism-sequence. synonym: "mWNK1/iso:m1" EXACT PRO-short-label [PRO:DAN] xref: UniProtKB:P83741-1 is_a: PR:P83741 ! serine/threonine-protein kinase WNK1 (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P83741-7 name: serine/threonine-protein kinase WNK1 isoform m7 (mouse) def: "A serine/threonine-protein kinase WNK1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P83741-7." [PRO:DNx, UniProtKB:P83741] comment: Category=organism-sequence. synonym: "mWNK1/iso:m7" EXACT PRO-short-label [PRO:DNx] synonym: "serine/threonine-protein kinase WNK1 isoform KS-WNK1 (mouse)" EXACT [UniProtKB:P83741] synonym: "serine/threonine-protein kinase WNK1 isoform Kidney-Specific (mouse)" EXACT [UniProtKB:P83741] xref: UniProtKB:P83741-7 is_a: PR:P83741 ! serine/threonine-protein kinase WNK1 (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P83741-6 name: serine/threonine-protein kinase WNK1 isoform m6 (mouse) def: "A serine/threonine-protein kinase WNK1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P83741-6. This form may arise due to intron retention." [PMID:15368895, PRO:HJD] comment: Category=organism-sequence. Note: Evidence from large-scale mRNA sequencing. synonym: "mWNK1/iso:m6" EXACT PRO-short-label [PRO:DAN] xref: UniProtKB:P83741-6 is_a: PR:P83741 ! serine/threonine-protein kinase WNK1 (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P83741-5 name: serine/threonine-protein kinase WNK1 isoform m5 (mouse) def: "A serine/threonine-protein kinase WNK1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P83741-5." [PMID:15489334, PRO:HJD] comment: Category=organism-sequence. Note: Evidence from large-scale mRNA sequencing. synonym: "mWNK1/iso:m5" EXACT PRO-short-label [PRO:DAN] xref: UniProtKB:P83741-5 is_a: PR:P83741 ! serine/threonine-protein kinase WNK1 (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P83741-4 name: serine/threonine-protein kinase WNK1 isoform m4 (mouse) def: "A serine/threonine-protein kinase WNK1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P83741-4. This form lacks the C-terminal region corresponding to residues 784 to 1032 of isoform 1." [PMID:15489334, PRO:HJD] comment: Category=organism-sequence. Note: Evidence from large-scale mRNA sequencing. synonym: "mWNK1/iso:m4" EXACT PRO-short-label [PRO:DAN] xref: UniProtKB:P83741-4 is_a: PR:P83741 ! serine/threonine-protein kinase WNK1 (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:000046059 name: serine/threonine-protein kinase WNK1 phosphorylated 1 (human) def: "A serine/threonine-protein kinase WNK1 (human) that has been phosphorylated on the residue at the position equivalent to Thr-60 of the amino acid sequence represented by UniProtKB:Q9H4A3-1. Example: UniProtKB:Q9H4A3-1, Thr-60, MOD:00047." [PMID:14611643, iPTMnet:Q9H4A3] comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:14611643). Status=unreviewed. synonym: "hWNK1/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q9H4A3-1, Thr-60, MOD:00047" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:Q9H4A3 ! serine/threonine-protein kinase WNK1 (human) relationship: has_part MOD:00047 ! O-phospho-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000037199 name: serine/threonine-protein kinase WNK1, brain and spinal cord isoform def: "A serine/threonine-protein kinase WNK1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P83741-2 or a 1:1 ortholog thereof. This form contains the region coded by the nervous system-specific exon HSN2 (as named in human and mouse)." [PMID:15060842, PMID:18521183, PRO:CNA] comment: Category=sequence. synonym: "WNK1/iso:bsc" EXACT PRO-short-label [PRO:DAN] is_a: PR:000017431 ! serine/threonine-protein kinase WNK1 [Term] id: PR:Q9JIH7-4 name: serine/threonine-protein kinase WNK1 isoform r4 (rat) def: "A serine/threonine-protein kinase WNK1 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9JIH7-4." [PRO:DNx, UniProtKB:Q9JIH7] comment: Category=organism-sequence. synonym: "rWNK1/iso:r4" EXACT PRO-short-label [PRO:DNx] synonym: "serine/threonine-protein kinase WNK1 isoform KS-WNK1-long (rat)" EXACT [UniProtKB:Q9JIH7] synonym: "serine/threonine-protein kinase WNK1 isoform Kidney-Specific long form (rat)" EXACT [UniProtKB:Q9JIH7] xref: UniProtKB:Q9JIH7-4 is_a: PR:Q9JIH7 ! serine/threonine-protein kinase WNK1 (rat) relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus [Term] id: PR:Q9JIH7-5 name: serine/threonine-protein kinase WNK1 isoform r5 (rat) def: "A serine/threonine-protein kinase WNK1 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9JIH7-5." [PRO:DNx, UniProtKB:Q9JIH7] comment: Category=organism-sequence. synonym: "rWNK1/iso:r5" EXACT PRO-short-label [PRO:DNx] synonym: "serine/threonine-protein kinase WNK1 isoform KS-WNK1-short (rat)" EXACT [UniProtKB:Q9JIH7] synonym: "serine/threonine-protein kinase WNK1 isoform Kidney-Specific short form (rat)" EXACT [UniProtKB:Q9JIH7] xref: UniProtKB:Q9JIH7-5 is_a: PR:Q9JIH7 ! serine/threonine-protein kinase WNK1 (rat) relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus [Term] id: PR:Q9JIH7-2 name: serine/threonine-protein kinase WNK1, dorsal root ganglia and sciatic nerve isoform (rat) def: "A serine/threonine-protein kinase WNK1, dorsal root ganglia and sciatic nerve isoform that is encoded in the genome of rat." [PRO:DAN] comment: Category=organism-sequence. synonym: "rWNK1/iso:drgsn" EXACT PRO-short-label [PRO:DNx] synonym: "serine/threonine-protein kinase WNK1 isoform 3 (rat)" EXACT [UniProtKB:Q9JIH7] synonym: "serine/threonine-protein kinase WNK1 isoform DRG and sciatic nerve variant (rat)" EXACT [UniProtKB:Q9JIH7] synonym: "serine/threonine-protein kinase WNK1 isoform Dorsal root ganglia and sciatic nerve variant (rat)" EXACT [UniProtKB:Q9JIH7] xref: UniProtKB:Q9JIH7-2 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000037201 ! serine/threonine-protein kinase WNK1, dorsal root ganglia and sciatic nerve isoform [Term] id: PR:Q9JIH7-3 name: serine/threonine-protein kinase WNK1, brain and spinal cord isoform (rat) def: "A serine/threonine-protein kinase WNK1, brain and spinal cord isoform that is encoded in the genome of rat." [PRO:DAN] comment: Category=organism-sequence. synonym: "rWNK1/iso:bsc" EXACT PRO-short-label [PRO:DNx] synonym: "serine/threonine-protein kinase WNK1 isoform 2 (rat)" EXACT [UniProtKB:Q9JIH7] synonym: "serine/threonine-protein kinase WNK1 isoform Brain and spinal cord variant (rat)" EXACT [UniProtKB:Q9JIH7] xref: UniProtKB:Q9JIH7-3 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000037199 ! serine/threonine-protein kinase WNK1, brain and spinal cord isoform [Term] id: PR:Q9JIH7-1 name: serine/threonine-protein kinase WNK1 isoform r1 (rat) def: "A serine/threonine-protein kinase WNK1 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9JIH7-1." [PRO:DNx, UniProtKB:Q9JIH7] comment: Category=organism-sequence. synonym: "rWnk1/iso:r1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9JIH7-1 is_a: PR:Q9JIH7 ! serine/threonine-protein kinase WNK1 (rat) relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus [Term] id: PR:000017431 name: serine/threonine-protein kinase WNK1 def: "A protein that is a translation product of the human WNK1 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "KDP" RELATED Gene-based [] synonym: "p65" BROAD [PRO:DNx] synonym: "HSN2" RELATED Gene-based [] synonym: "WNK1" EXACT PRO-short-label [PRO:DNx] synonym: "PRKWNK1" RELATED Gene-based [] synonym: "KIAA0344" RELATED Gene-based [] synonym: "protein HSN2" RELATED [] synonym: "kinase deficient protein" EXACT [] synonym: "erythrocyte 65 kDa protein" EXACT [] synonym: "protein kinase with no lysine 1" EXACT [] synonym: "protein kinase lysine-deficient 1" EXACT [] xref: IUPHARobj:2280 is_a: PR:000000001 ! protein [Term] id: PR:000037201 name: serine/threonine-protein kinase WNK1, dorsal root ganglia and sciatic nerve isoform def: "A serine/threonine-protein kinase WNK1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P83741-3 or a 1:1 ortholog thereof. This form contains the region coded by the nervous system-specific exon HSN2 (as named in human and mouse)." [PMID:15060842, PMID:18521183, PRO:HJD] comment: Category=sequence. synonym: "WNK1/iso:drgsn" EXACT PRO-short-label [PRO:DAN] synonym: "WNK1 DRG and sciatic nerve variant" RELATED [] synonym: "WNK1 dorsal root ganglia and sciatic nerve variant" RELATED [] is_a: PR:000017431 ! serine/threonine-protein kinase WNK1 [Term] id: PR:Q9H4A3-6 name: serine/threonine-protein kinase WNK1, dorsal root ganglia and sciatic nerve isoform (human) def: "A serine/threonine-protein kinase WNK1, dorsal root ganglia and sciatic nerve isoform that is encoded in the genome of human." [PMID:15060842, PRO:CNA] comment: Category=organism-sequence. synonym: "hWNK1/iso:drgsn" EXACT PRO-short-label [PRO:DAN] synonym: "WNK1 DRG and sciatic nerve variant" RELATED Gene-based [UniProtKB:Q9H4A3] synonym: "serine/threonine-protein kinase WNK1 isoform 5" RELATED Gene-based [UniProtKB:Q9H4A3] synonym: "WNK1 dorsal root ganglia and sciatic nerve variant" RELATED Gene-based [UniProtKB:Q9H4A3] xref: UniProtKB:Q9H4A3-6 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000037201 ! serine/threonine-protein kinase WNK1, dorsal root ganglia and sciatic nerve isoform [Term] id: PR:Q9H4A3-7 name: serine/threonine-protein kinase WNK1 isoform h6 (human) def: "A serine/threonine-protein kinase WNK1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H4A3-7." [PRO:DNx, UniProtKB:Q9H4A3] comment: Category=organism-sequence. synonym: "hWNK1/iso:h6" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9H4A3-7 is_a: PR:Q9H4A3 ! serine/threonine-protein kinase WNK1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q9H4A3-4 name: serine/threonine-protein kinase WNK1, kidney-specific isoform (human) def: "A serine/threonine-protein kinase WNK1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H4A3-4." [PRO:DNx, UniProtKB:Q9H4A3] comment: Category=organism-sequence. synonym: "hWNK1/iso:k" EXACT PRO-short-label [PRO:DNx] synonym: "serine/threonine-protein kinase WNK1 isoform KS-WNK1 (human)" EXACT [UniProtKB:Q9H4A3] synonym: "serine/threonine-protein kinase WNK1 isoform Kidney-Specific (human)" EXACT [UniProtKB:Q9H4A3] xref: UniProtKB:Q9H4A3-4 is_a: PR:Q9H4A3 ! serine/threonine-protein kinase WNK1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q9H4A3-5 name: serine/threonine-protein kinase WNK1 isoform h4 (human) def: "A serine/threonine-protein kinase WNK1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H4A3-5." [PMID:15060842, PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hWNK1/iso:h4" EXACT PRO-short-label [PRO:DAN] synonym: "WNK1 brain and spinal cord variant" RELATED [] synonym: "serine/threonine-protein kinase WNK1 isoform 4" RELATED Gene-based [UniProtKB:Q9H4A3] xref: UniProtKB:Q9H4A3-5 is_a: PR:Q9H4A3 ! serine/threonine-protein kinase WNK1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q9H4A3-2 name: serine/threonine-protein kinase WNK1 isoform h2 (human) def: "A serine/threonine-protein kinase WNK1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H4A3-2." [PRO:DNx, UniProtKB:Q9H4A3] comment: Category=organism-sequence. synonym: "hWNK1/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9H4A3-2 is_a: PR:Q9H4A3 ! serine/threonine-protein kinase WNK1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q9H4A3-1 name: serine/threonine-protein kinase WNK1 isoform h1 (human) def: "A serine/threonine-protein kinase WNK1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H4A3-1." [PRO:DNx, UniProtKB:Q9H4A3] comment: Category=organism-sequence. synonym: "hWNK1/iso:h1" EXACT PRO-short-label [PRO:DNx] synonym: "serine/threonine-protein kinase WNK1 isoform L-WNK1 (human)" EXACT [UniProtKB:Q9H4A3] xref: UniProtKB:Q9H4A3-1 is_a: PR:Q9H4A3 ! serine/threonine-protein kinase WNK1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q9H4A3 name: serine/threonine-protein kinase WNK1 (human) def: "A serine/threonine-protein kinase WNK1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9H4A3] comment: Category=organism-gene. synonym: "KDP" RELATED Gene-based [UniProtKB:Q9H4A3] synonym: "HSN2" RELATED Gene-based [UniProtKB:Q9H4A3] synonym: "WNK1" RELATED Gene-based [UniProtKB:Q9H4A3] synonym: "hWNK1" EXACT PRO-short-label [PRO:DNx] synonym: "PRKWNK1" RELATED Gene-based [UniProtKB:Q9H4A3] synonym: "KIAA0344" RELATED Gene-based [UniProtKB:Q9H4A3] synonym: "p65 (human)" BROAD [UniProtKB:Q9H4A3] synonym: "kinase deficient protein (human)" EXACT [UniProtKB:Q9H4A3] synonym: "erythrocyte 65 kDa protein (human)" EXACT [UniProtKB:Q9H4A3] synonym: "protein kinase with no lysine 1 (human)" EXACT [UniProtKB:Q9H4A3] synonym: "protein kinase lysine-deficient 1 (human)" EXACT [UniProtKB:Q9H4A3] xref: Reactome:R-HSA-2672391 "PR:Q9H4A3 located_in GO:0005829" xref: DTO:03100567 xref: UniProtKB:Q9H4A3 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000017431 ! serine/threonine-protein kinase WNK1 relationship: has_gene_template HGNC:14540 ! WNK1 (human) [Term] id: PR:Q9JIH7 name: serine/threonine-protein kinase WNK1 (rat) def: "A serine/threonine-protein kinase WNK1 that is encoded in the genome of rat." [OMA:Q9JIH7, PRO:DAN] comment: Category=organism-gene. synonym: "Hsn2" RELATED Gene-based [UniProtKB:Q9JIH7] synonym: "Wnk1" RELATED Gene-based [UniProtKB:Q9JIH7] synonym: "rWNK1" EXACT PRO-short-label [PRO:DAN] synonym: "Prkwnk1" RELATED Gene-based [UniProtKB:Q9JIH7] synonym: "protein kinase with no lysine 1 (rat)" EXACT [UniProtKB:Q9JIH7] synonym: "protein kinase lysine-deficient 1 (rat)" EXACT [UniProtKB:Q9JIH7] xref: UniProtKB:Q9JIH7 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000017431 ! serine/threonine-protein kinase WNK1 relationship: has_gene_template RGD:621141 ! Wnk1 (rat) [Term] id: PR:P83741 name: serine/threonine-protein kinase WNK1 (mouse) def: "A serine/threonine-protein kinase WNK1 that is encoded in the genome of mouse." [OMA:P83741, PRO:DNx] comment: Category=organism-gene. synonym: "Hsn2" RELATED Gene-based [UniProtKB:P83741] synonym: "Wnk1" RELATED Gene-based [UniProtKB:P83741] synonym: "mWNK1" EXACT PRO-short-label [PRO:DNx] synonym: "Prkwnk1" RELATED Gene-based [UniProtKB:P83741] synonym: "protein kinase with no lysine 1 (mouse)" EXACT [UniProtKB:P83741] synonym: "protein kinase lysine-deficient 1 (mouse)" EXACT [UniProtKB:P83741] xref: UniProtKB:P83741 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000017431 ! serine/threonine-protein kinase WNK1 relationship: has_gene_template MGI:2442092 ! Wnk1 (mouse)