[Term] id: PR:Q01831 name: DNA repair protein complementing XP-C cells (human) def: "A DNA repair protein complementing XP-C cells that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q01831] comment: Category=organism-gene. synonym: "XPC" RELATED Gene-based [UniProtKB:Q01831] synonym: "XPCC" RELATED Gene-based [UniProtKB:Q01831] synonym: "hXPC" EXACT PRO-short-label [PRO:DNx] synonym: "p125 (human)" BROAD [UniProtKB:Q01831] synonym: "xeroderma pigmentosum group C-complementing protein (human)" EXACT [UniProtKB:Q01831] xref: UniProtKB:Q01831 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000017494 ! DNA repair protein complementing XP-C cells relationship: has_gene_template HGNC:12816 ! XPC (human) [Term] id: PR:000049710 name: DNA repair protein complementing XP-C cells, initiator methionine removed ubiquitinated form (human) def: "A DNA repair protein complementing XP-C cells (human) that has had the initiator methionine removed and that includes at least one ubiquitinated lysine. UniProtKB:Q01831, 2-940, MOD:01148." [PRO:DNx, Reactome:R-HSA-6782944] comment: Category=organism-modification. synonym: "hXPC/InitMet-/UbiqLys+" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000218293, MOD:01148" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q01831, 2-940, MOD:01148" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-6782944 "PR:000049710 located_in GO:0005654" intersection_of: has_part MOD:01148 ! ubiquitinylated lysine intersection_of: lacks_part PR:000021937 ! initiator methionine intersection_of: PR:Q01831 ! DNA repair protein complementing XP-C cells (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q01831-1 name: DNA repair protein complementing XP-C cells isoform h1 (human) def: "A DNA repair protein complementing XP-C cells (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q01831-1." [PRO:DNx, UniProtKB:Q01831] comment: Category=organism-sequence. synonym: "hXPC/iso:h1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q01831-1 is_a: PR:Q01831 ! DNA repair protein complementing XP-C cells (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000049708 name: DNA repair protein complementing XP-C cells, initiator methionine removed form (human) def: "A DNA repair protein complementing XP-C cells (human) that has had the initiator methionine removed. UniProtKB:Q01831, 2-940." [PRO:DNx, Reactome:R-HSA-67441] comment: Category=organism-modification. synonym: "hXPC/InitMet-" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000218293" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q01831, 2-940" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-67441 "PR:000049708 located_in GO:0005654" intersection_of: lacks_part PR:000021937 ! initiator methionine intersection_of: PR:Q01831 ! DNA repair protein complementing XP-C cells (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000049709 name: DNA repair protein complementing XP-C cells, initiator methionine removed sumoylated 1 (human) def: "A DNA repair protein complementing XP-C cells (human) that has had the initiator methionine removed and has been post-translationally modified to include sumoylated lysine at position 655 of the amino acid sequence represented by UniProtKB:Q01831. UniProtKB:Q01831, 2-940, Lys-655, MOD:01149." [PRO:DNx, Reactome:R-HSA-4570458] comment: Category=organism-modification. synonym: "hXPC/InitMet-/Sumo:1" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000218293, Lys-655, MOD:01149" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q01831, 2-940, Lys-655, MOD:01149" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-4570458 "PR:000049709 located_in GO:0005654" is_a: PR:Q01831 ! DNA repair protein complementing XP-C cells (human) relationship: has_part MOD:01149 ! sumoylated lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:Q01831-2 name: DNA repair protein complementing XP-C cells isoform h2 (human) def: "A DNA repair protein complementing XP-C cells (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q01831-2." [PRO:DNx, UniProtKB:Q01831] comment: Category=organism-sequence. synonym: "hXPC/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q01831-2 is_a: PR:Q01831 ! DNA repair protein complementing XP-C cells (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q01831-3 name: DNA repair protein complementing XP-C cells isoform h3 (human) def: "A DNA repair protein complementing XP-C cells (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q01831-3." [PRO:DNx, UniProtKB:Q01831] comment: Category=organism-sequence. synonym: "hXPC/iso:h3" EXACT PRO-short-label [PRO:DNx] synonym: "DNA repair protein complementing XP-C cells isoform B (human)" EXACT [UniProtKB:Q01831] xref: UniProtKB:Q01831-3 is_a: PR:Q01831 ! DNA repair protein complementing XP-C cells (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000017494 name: DNA repair protein complementing XP-C cells def: "A protein that is a translation product of the human XPC gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "XPC" EXACT PRO-short-label [PRO:DNx] synonym: "XPCC" RELATED Gene-based [] synonym: "p125" BROAD [PRO:DNx] synonym: "xeroderma pigmentosum group C-complementing protein" EXACT [] synonym: "xeroderma pigmentosum group C-complementing protein homolog" EXACT [] is_a: PR:000000001 ! protein