[Term] id: PR:000017509 name: X-ray repair cross-complementing protein 6 def: "A protein that is a translation product of the human XRCC6 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "Ku70" RELATED Gene-based [] synonym: "TLAA" RELATED [] synonym: "CTC75" EXACT [] synonym: "CTCBF" RELATED [] synonym: "G22P1" RELATED Gene-based [] synonym: "XRCC6" EXACT PRO-short-label [PRO:DNx] synonym: "DNA repair protein XRCC6" EXACT [] synonym: "thyroid-lupus autoantigen" RELATED [] synonym: "70 kDa subunit of Ku antigen" EXACT [] synonym: "lupus Ku autoantigen protein p70" EXACT [] synonym: "Ku autoantigen protein p70 homolog" EXACT [] synonym: "5'-deoxyribose-5-phosphate lyase Ku70" EXACT [] synonym: "CTC box-binding factor 75 kDa subunit" EXACT [] synonym: "ATP-dependent DNA helicase 2 subunit 1" EXACT [] synonym: "ATP-dependent DNA helicase II 70 kDa subunit" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:P12956 name: X-ray repair cross-complementing protein 6 (human) def: "An X-ray repair cross-complementing protein 6 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P12956] comment: Category=organism-gene. synonym: "G22P1" RELATED Gene-based [UniProtKB:P12956] synonym: "XRCC6" RELATED Gene-based [UniProtKB:P12956] synonym: "hXRCC6" EXACT PRO-short-label [PRO:DNx] synonym: "Ku70 (human)" EXACT [UniProtKB:P12956] synonym: "TLAA (human)" BROAD [UniProtKB:P12956] synonym: "CTC75 (human)" EXACT [UniProtKB:P12956] synonym: "CTCBF (human)" BROAD [UniProtKB:P12956] synonym: "5'-dRP lyase Ku70 (human)" EXACT [UniProtKB:P12956] synonym: "DNA repair protein XRCC6 (human)" EXACT [UniProtKB:P12956] synonym: "thyroid-lupus autoantigen (human)" BROAD [UniProtKB:P12956] synonym: "70 kDa subunit of Ku antigen (human)" EXACT [UniProtKB:P12956] synonym: "lupus Ku autoantigen protein p70 (human)" EXACT [UniProtKB:P12956] synonym: "5'-deoxyribose-5-phosphate lyase Ku70 (human)" EXACT [UniProtKB:P12956] synonym: "CTC box-binding factor 75 kDa subunit (human)" EXACT [UniProtKB:P12956] synonym: "ATP-dependent DNA helicase 2 subunit 1 (human)" EXACT [UniProtKB:P12956] synonym: "ATP-dependent DNA helicase II 70 kDa subunit (human)" EXACT [UniProtKB:P12956] synonym: "X-ray repair complementing defective repair in Chinese hamster cells 6 (human)" EXACT [UniProtKB:P12956] xref: UniProtKB:P12956 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000017509 ! X-ray repair cross-complementing protein 6 relationship: has_gene_template HGNC:4055 ! XRCC6 (human) [Term] id: PR:P12956-2 name: X-ray repair cross-complementing protein 6 isoform h2 (human) def: "An X-ray repair cross-complementing protein 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P12956-2." [PRO:DNx, UniProtKB:P12956] comment: Category=organism-sequence. synonym: "hXRCC6/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P12956-2 is_a: PR:P12956 ! X-ray repair cross-complementing protein 6 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P12956-1 name: X-ray repair cross-complementing protein 6 isoform h1 (human) def: "An X-ray repair cross-complementing protein 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P12956-1." [PRO:DNx, UniProtKB:P12956] comment: Category=organism-sequence. synonym: "hXRCC6/iso:h1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P12956-1 is_a: PR:P12956 ! X-ray repair cross-complementing protein 6 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000049714 name: X-ray repair cross-complementing protein 6, initiator methionine removed form (human) def: "An X-ray repair cross-complementing protein 6 (human) that has had the initiator methionine removed. UniProtKB:P12956, 2-609." [PRO:DNx, Reactome:R-HSA-3134813, Reactome:R-HSA-58272] comment: Category=organism-modification. synonym: "PRO_0000210179" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hXRCC6/InitMet-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P12956, 2-609" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-58272 "PR:000049714 located_in GO:0005654" xref: Reactome:R-HSA-3134813 "PR:000049714 located_in GO:0005829" xref: Reactome:R-HSA-6806444 "PR:000049714 located_in GO:0005576" xref: Reactome:R-HSA-6801300 "PR:000049714 located_in GO:1904813" xref: Reactome:R-HSA-6801312 "PR:000049714 located_in GO:0034774" intersection_of: lacks_part PR:000021937 ! initiator methionine intersection_of: PR:P12956 ! X-ray repair cross-complementing protein 6 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens