[Term]
id: PR:000024845
name: alpha-2-macroglobulin
def: "A protein that is a translation product of the human A2M gene or a 1:1 ortholog thereof." [PRO:DAN]
comment: Category=gene.
synonym: "A2M" EXACT PRO-short-label [PRO:DNx]
synonym: "CPAMD5" RELATED Gene-based []
synonym: "FWP007" RELATED Gene-based []
synonym: "alpha-2-M" EXACT []
synonym: "C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000046213
name: alpha-2-macroglobulin, signal peptide removed form (human)
def: "An alpha-2-macroglobulin (human) that has had the signal peptide removed. UniProtKB:P01023, 24-1474." [PRO:DNx, Reactome:R-HSA-139834, Reactome:R-HSA-200618, Reactome:R-HSA-49291]
comment: Category=organism-modification.
synonym: "hA2M/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000000055" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P01023, 24-1474" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-139834 "PR:000046213 located_in GO:0031093"
xref: Reactome:R-HSA-49291 "PR:000046213 located_in GO:0005576"
xref: Reactome:R-HSA-200618 "PR:000046213 located_in GO:0005829"
intersection_of: PR:P01023 ! alpha-2-macroglobulin (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000024848
name: alpha-2-macroglobulin, signal peptide removed form
def: "An alpha-2-macroglobulin that has had the signal peptide removed." [PRO:DAN]
comment: Category=modification.
synonym: "A2M/SigPep-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000024845 ! alpha-2-macroglobulin
intersection_of: lacks_part SO:0000418 ! signal_peptide

[Term]
id: PR:P01023
name: alpha-2-macroglobulin (human)
def: "An alpha-2-macroglobulin that is encoded in the genome of human." [PRO:DAN]
comment: Category=organism-gene.
synonym: "A2M" RELATED Gene-based [UniProtKB:P01023]
synonym: "hA2M" EXACT PRO-short-label [PRO:DNx]
synonym: "CPAMD5" RELATED Gene-based [UniProtKB:P01023]
synonym: "FWP007" RELATED Gene-based [UniProtKB:P01023]
synonym: "alpha-2-M (human)" EXACT [UniProtKB:P01023]
synonym: "C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5 (human)" EXACT [UniProtKB:P01023]
xref: UniProtKB:P01023
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000024845 ! alpha-2-macroglobulin
relationship: has_gene_template HGNC:7 ! A2M (human)

[Term]
id: PR:Q6GQT1
name: alpha-2-macroglobulin-P (mouse)
def: "An alpha-2-macroglobulin that is encoded in the genome of mouse." [OMA:Q6GQT1, PRO:DNx]
comment: Category=organism-gene.
synonym: "A2m" RELATED Gene-based [UniProtKB:Q6GQT1]
synonym: "A2mp" RELATED Gene-based [UniProtKB:Q6GQT1]
synonym: "mA2M" EXACT PRO-short-label [PRO:DNx]
synonym: "alpha-2-macroglobulin (mouse)" RELATED [UniProtKB:Q6GQT1]
xref: UniProtKB:Q6GQT1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000024845 ! alpha-2-macroglobulin
relationship: has_gene_template MGI:2449119 ! A2m (mouse)

[Term]
id: PR:P06238
name: alpha-2-macroglobulin (rat)
def: "An alpha-2-macroglobulin that is encoded in the genome of rat." [OMA:P06238, PRO:DNx]
comment: Category=organism-gene.
synonym: "A2m" RELATED Gene-based [UniProtKB:P06238]
synonym: "A2m1" RELATED Gene-based [UniProtKB:P06238]
synonym: "rA2M" EXACT PRO-short-label [PRO:DNx]
synonym: "alpha-2-M (rat)" EXACT [UniProtKB:P06238]
xref: UniProtKB:P06238
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000024845 ! alpha-2-macroglobulin
relationship: has_gene_template RGD:2004 ! A2m (rat)