[Term]
id: PR:P12931
name: proto-oncogene tyrosine-protein kinase Src (human)
def: "A proto-oncogene tyrosine-protein kinase Src that is encoded in the genome of human." [PRO:CNA, UniProtKB:P12931]
comment: Category=organism-gene.
synonym: "SRC" RELATED Gene-based [UniProtKB:P12931]
synonym: "SRC1" RELATED Gene-based [UniProtKB:P12931]
synonym: "hSRC" EXACT PRO-short-label [PRO:DNx]
synonym: "p60-Src (human)" EXACT [UniProtKB:P12931]
synonym: "pp60c-src (human)" EXACT [UniProtKB:P12931]
synonym: "proto-oncogene c-Src (human)" EXACT [UniProtKB:P12931]
xref: Reactome:R-HSA-9628701 "PR:P12931 located_in GO:0005829"
xref: DTO:03100484
xref: UniProtKB:P12931
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027234 ! proto-oncogene tyrosine-protein kinase Src
relationship: has_gene_template HGNC:11283 ! SRC (human)

[Term]
id: PR:P12931-2
name: proto-oncogene tyrosine-protein kinase Src isoform 2 (human)
def: "A proto-oncogene tyrosine-protein kinase Src isoform 2 that is encoded in the genome of human." [PMID:1691439, PRO:CNA]
comment: Category=organism-sequence.
synonym: "hSRC/iso:2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P12931-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027239 ! proto-oncogene tyrosine-protein kinase Src isoform 2

[Term]
id: PR:000027234
name: proto-oncogene tyrosine-protein kinase Src
def: "A proto-oncogene SRC-like tyrosine-protein kinase that is a translation product of the human SRC gene or a 1:1 ortholog thereof." [PMID:18789131, PRO:CNA]
comment: Category=gene.
synonym: "SRC" EXACT PRO-short-label [PRO:DNx]
synonym: "SRC1" RELATED Gene-based []
synonym: "p60-Src" EXACT []
synonym: "pp60c-src" EXACT []
synonym: "Proto-oncogene c-Src" EXACT []
xref: IUPHARobj:2206
is_a: PR:000002997 ! proto-oncogene SRC-like tyrosine-protein kinase

[Term]
id: PR:000027238
name: proto-oncogene tyrosine-protein kinase Src isoform 1 phosphorylated 1 (human)
def: "A proto-oncogene tyrosine-protein kinase Src isoform 1 phosphorylated 1 in human. UniProtKB:P12931-1, Tyr-419, MOD:00048." [PMID:8789131, PRO:PD]
comment: Category=organism-modification. Note that the Src residue number in cited article is based on the chicken Src protein.
synonym: "hSRC/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P12931-1, Tyr-419, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-112331 "PR:000027238 located_in GO:0005886"
xref: Reactome:R-HSA-377592 "PR:000027238 located_in GO:0005829"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027237 ! proto-oncogene tyrosine-protein kinase Src isoform 1 phosphorylated 1
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine

[Term]
id: PR:P12931-1
name: proto-oncogene tyrosine-protein kinase Src isoform 1 (human)
def: "A proto-oncogene tyrosine-protein kinase Src isoform 1 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hSRC/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P12931-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027235 ! proto-oncogene tyrosine-protein kinase Src isoform 1

[Term]
id: PR:000045674
name: proto-oncogene tyrosine-protein kinase Src phosphorylated 1 (human)
def: "A proto-oncogene tyrosine-protein kinase Src (human) that has been phosphorylated on the residue at the position equivalent to Ser-75 of the amino acid sequence represented by UniProtKB:P12931-1. Example: UniProtKB:P12931-1, Ser-75, MOD:00046." [PMID:10544291, iPTMnet:P12931]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:10544291). Status=unreviewed.
synonym: "hSRC/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P12931-1, Ser-75, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P12931 ! proto-oncogene tyrosine-protein kinase Src (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens