[Term]
id: PR:Q8N726-2
name: tumor suppressor smARF (human)
def: "A CDKN2A gene translation product (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8N726-2." [PRO:DAN, UniProtKB:Q8N726]
comment: Category=organism-sequence.
synonym: "hCDKN2A/iso:smARF" EXACT PRO-short-label [PRO:DNx]
synonym: "cyclin-dependent kinase inhibitor 2A isoform p14ARF (human)" EXACT [UniProtKB:Q8N726]
xref: UniProtKB:Q8N726-2
is_a: PR:000030011 ! CDKN2A gene translation product (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q8N726-1
name: tumor suppressor ARF (human)
def: "A tumor suppressor ARF that is encoded in the genome of human." [PRO:DAN]
comment: Category=organism-sequence.
synonym: "hCDKN2A/iso:ARF" EXACT PRO-short-label [PRO:DNx]
synonym: "CDKN2A isoform 4 (human)" EXACT [PRO:DNx]
synonym: "cyclin-dependent kinase inhibitor 2A isoform 4 (human)" EXACT [UniProtKB:Q8N726]
synonym: "cyclin-dependent kinase inhibitor 2A isoform p19ARF (human)" EXACT [UniProtKB:Q8N726]
xref: UniProtKB:Q8N726-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000029146 ! tumor suppressor ARF

[Term]
id: PR:Q8QZZ9-1
name: tumor suppressor ARF (rat)
def: "A Cdkn2a gene translation product (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8QZZ9-1." [PRO:DNx, UniProtKB:Q8QZZ9]
comment: Category=organism-sequence.
synonym: "rCdkn2a/iso:ARF" EXACT PRO-short-label [PRO:DNx]
synonym: "tumor suppressor ARF isoform p19ARF (rat)" EXACT [UniProtKB:Q8QZZ9]
xref: UniProtKB:Q8QZZ9-1
is_a: PR:000036484 ! Cdkn2a gene translation product (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:000030011
name: CDKN2A gene translation product (human)
def: "A CDKN2A gene translation product that is encoded in the genome of human." [PRO:DAN]
comment: Category=organism-gene.
synonym: "hCDKN2A" EXACT PRO-short-label [PRO:DNx]
synonym: "cyclin-dependent kinase inhibitor 2A (human)" RELATED [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000029097 ! CDKN2A gene translation product
relationship: has_gene_template HGNC:1787 ! CDKN2A (human)

[Term]
id: PR:000036329
name: Cdkn2a gene translation product (mouse)
def: "A CDKN2A gene translation product that is encoded in the genome of mouse." [PRO:DAN]
comment: Category=organism-gene.
synonym: "mCDKN2A" EXACT PRO-short-label [PRO:DNx]
synonym: "ARF (mouse)" NARROW [UniProtKB:Q64364]
synonym: "p19ARF (mouse)" NARROW [UniProtKB:Q64364]
synonym: "alternative reading frame (mouse)" NARROW [UniProtKB:Q64364]
synonym: "cyclin-dependent kinase inhibitor 2A (mouse)" NARROW [UniProtKB:Q64364]
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000029097 ! CDKN2A gene translation product
relationship: has_gene_template MGI:104738 ! Cdkn2a (mouse)

[Term]
id: PR:P42771
name: cyclin-dependent kinase inhibitor 2A, isoforms h1/h2/h3/h5 (human)
def: "A cyclin-dependent kinase inhibitor 2A (human), isoforms h1, h2, h3, and h5." [PRO:DAN, UniProtKB:P42771]
comment: Category=organism-seqgroup.
synonym: "hCDKN2A/iso:[1/2/3/5]" EXACT PRO-short-label [PRO:DNx]
xref: Reactome:R-HSA-182578 "PR:P42771 located_in GO:0005829"
xref: UniProtKB:P42771
is_a: PR:000030011 ! CDKN2A gene translation product (human)
union_of: PR:P42771-1 ! cyclin-dependent kinase inhibitor 2A isoform h1 (human)
union_of: PR:P42771-2 ! cyclin-dependent kinase inhibitor 2A isoform h2 (human)
union_of: PR:P42771-3 ! cyclin-dependent kinase inhibitor 2A isoform h3 (human)
union_of: PR:P42771-4 ! cyclin-dependent kinase inhibitor 2A isoform h5 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000029143
name: cyclin-dependent kinase inhibitor 2A isoform 1
def: "A CDKN2A gene translation product that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P42771-1 or a 1:1 ortholog thereof." [PRO:DAN]
comment: Category=sequence.
synonym: "CDKN2A/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000029097 ! CDKN2A gene translation product

[Term]
id: PR:000029144
name: cyclin-dependent kinase inhibitor 2A isoform 2
def: "A CDKN2A gene translation product that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P42771-2 or a 1:1 ortholog thereof." [PRO:DAN]
comment: Category=sequence.
synonym: "CDKN2A/iso:2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000029097 ! CDKN2A gene translation product

[Term]
id: PR:000029145
name: cyclin-dependent kinase inhibitor 2A isoform 3
def: "A CDKN2A gene translation product that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P42771-3 or a 1:1 ortholog thereof." [PRO:DAN]
comment: Category=sequence.
synonym: "CDKN2A/iso:3" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000029097 ! CDKN2A gene translation product

[Term]
id: PR:000029146
name: tumor suppressor ARF
def: "A CDKN2A gene translation product that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8N726-1 or a 1:1 ortholog thereof." [PRO:DAN]
comment: Category=sequence.
synonym: "CDKN2A/iso:ARF" EXACT PRO-short-label [PRO:DNx]
synonym: "CDKN2A isoform 4" EXACT [PRO:DNx]
synonym: "cyclin-dependent kinase inhibitor 2A isoform 4" EXACT [PRO:DNx]
synonym: "cyclin-dependent kinase inhibitor 2A isoform ARF" EXACT [PRO:DNx]
is_a: PR:000029097 ! CDKN2A gene translation product

[Term]
id: PR:000029147
name: cyclin-dependent kinase inhibitor 2A isoform 5
def: "A CDKN2A gene translation product that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P42771-4 or a 1:1 ortholog thereof." [PRO:DAN]
comment: Category=sequence.
synonym: "CDKN2A/iso:5" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000029097 ! CDKN2A gene translation product

[Term]
id: PR:P42771-4
name: cyclin-dependent kinase inhibitor 2A isoform h5 (human)
def: "A cyclin-dependent kinase inhibitor 2A isoform 5 that is encoded in the genome of human." [PRO:DAN]
comment: Category=organism-sequence.
synonym: "hCDKN2A/iso:5" EXACT PRO-short-label [PRO:DNx]
synonym: "cyclin-dependent kinase inhibitor 2A isoform p16gamma (human)" EXACT [UniProtKB:P42771]
xref: UniProtKB:P42771-4
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000029147 ! cyclin-dependent kinase inhibitor 2A isoform 5

[Term]
id: PR:P51480
name: cyclin-dependent kinase inhibitor 2A isoforms m1/m2 (mouse)
def: "A cyclin-dependent kinase inhibitor 2A (mouse), isoforms m1 and m2." [PRO:DAN, UniProtKB:P51480]
comment: Category=organism-seqgroup.
synonym: "mCdkn2a/iso:[1/2]" EXACT PRO-short-label [PRO:DAN]
xref: UniProtKB:P51480
is_a: PR:000036329 ! Cdkn2a gene translation product (mouse)
union_of: PR:P51480-1 ! cyclin-dependent kinase inhibitor 2A isoform m1 (mouse)
union_of: PR:P51480-2 ! cyclin-dependent kinase inhibitor 2A isoform m2 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P42771-1
name: cyclin-dependent kinase inhibitor 2A isoform h1 (human)
def: "A cyclin-dependent kinase inhibitor 2A isoform 1 that is encoded in the genome of human." [PRO:DAN]
comment: Category=organism-sequence.
synonym: "hCDKN2A/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "cyclin-dependent kinase inhibitor 2A isoform p16INK4a (human)" EXACT [UniProtKB:P42771]
xref: UniProtKB:P42771-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000029143 ! cyclin-dependent kinase inhibitor 2A isoform 1

[Term]
id: PR:Q64364-1
name: tumor suppressor ARF (mouse)
def: "A Cdkn2a gene translation product (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q64364-1." [PRO:DNx, UniProtKB:Q64364]
comment: Category=organism-sequence.
synonym: "mCdkn2a/iso:ARF" EXACT PRO-short-label [PRO:DAN]
synonym: "tumor suppressor ARF isoform p19ARF (mouse)" EXACT [UniProtKB:Q64364]
xref: UniProtKB:Q64364-1
is_a: PR:000036329 ! Cdkn2a gene translation product (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q64364-2
name: tumor suppressor smARF (mouse)
def: "A Cdkn2a gene translation product (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q64364-2." [PRO:DNx, UniProtKB:Q64364]
comment: Category=organism-sequence.
synonym: "mCdkn2a/iso:smARF" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q64364-2
is_a: PR:000036329 ! Cdkn2a gene translation product (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P42771-2
name: cyclin-dependent kinase inhibitor 2A isoform h2 (human)
def: "A cyclin-dependent kinase inhibitor 2A isoform 2 that is encoded in the genome of human." [PRO:DAN]
comment: Category=organism-sequence.
synonym: "hCDKN2A/iso:2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P42771-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000029144 ! cyclin-dependent kinase inhibitor 2A isoform 2

[Term]
id: PR:P51480-2
name: cyclin-dependent kinase inhibitor 2A isoform m2 (mouse)
def: "A Cdkn2a gene translation product (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51480-2." [PRO:DNx, UniProtKB:P51480]
comment: Category=organism-sequence.
synonym: "mCdkn2a/iso:m2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P51480-2
is_a: PR:000036329 ! Cdkn2a gene translation product (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q64364
name: tumor suppressor ARF/smARF (mouse)
def: "A Cdkn2a gene translation product (mouse), isoforms ARF and smARF." [PRO:DAN, UniProtKB:Q64364]
comment: Category=organism-seqgroup.
synonym: "mCdkn2a/iso:[ARF/smARF]" EXACT PRO-short-label [PRO:DAN]
xref: UniProtKB:Q64364
is_a: PR:000036329 ! Cdkn2a gene translation product (mouse)
union_of: PR:Q64364-1 ! tumor suppressor ARF (mouse)
union_of: PR:Q64364-2 ! tumor suppressor smARF (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P51480-1
name: cyclin-dependent kinase inhibitor 2A isoform m1 (mouse)
def: "A Cdkn2a gene translation product (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51480-1." [PRO:DNx, UniProtKB:P51480]
comment: Category=organism-sequence.
synonym: "mCdkn2a/iso:m1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P51480-1
is_a: PR:000036329 ! Cdkn2a gene translation product (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q8N726
name: tumor suppressor ARF/smARF (human)
def: "A CDKN2A gene translation product (human), isoforms ARF and smARF." [PRO:DAN, UniProtKB:Q8N726]
comment: Category=organism-seqgroup.
synonym: "hCDKN2A/iso:[ARF/smARF]" EXACT PRO-short-label [PRO:DAN]
synonym: "cyclin-dependent kinase inhibitor 2A isoforms 4/6 (human)" RELATED [PRO:DAN]
xref: Reactome:R-HSA-1629813 "PR:Q8N726 located_in GO:0005654"
xref: Reactome:R-HSA-9645669 "PR:Q8N726 located_in GO:0005829"
xref: Reactome:R-HSA-9645695 "PR:Q8N726 located_in GO:0005759"
xref: UniProtKB:Q8N726
is_a: PR:000030011 ! CDKN2A gene translation product (human)
union_of: PR:Q8N726-1 ! tumor suppressor ARF (human)
union_of: PR:Q8N726-2 ! tumor suppressor smARF (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9R0Z3-1
name: cyclin-dependent kinase inhibitor 2A isoform r1 (rat)
def: "A Cdkn2a gene translation product (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9R0Z3-1." [PRO:DNx, UniProtKB:Q9R0Z3]
comment: Category=organism-sequence.
synonym: "rCdkn2a/iso:r1" EXACT PRO-short-label [PRO:DNx]
synonym: "tumor suppressor ARF isoform p16INK4a (rat)" EXACT [UniProtKB:Q9R0Z3]
xref: UniProtKB:Q9R0Z3-1
is_a: PR:000036484 ! Cdkn2a gene translation product (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:000036484
name: Cdkn2a gene translation product (rat)
def: "A CDKN2A gene translation product that is encoded in the genome of rat." [PRO:DAN]
comment: Category=organism-gene.
synonym: "rCDKN2A" EXACT PRO-short-label [PRO:DNx]
synonym: "ARF (rat)" NARROW [UniProtKB:Q8QZZ9]
synonym: "p16-INK4a" NARROW [UniProtKB:Q9R0Z3]
synonym: "CDK4I (rat)" NARROW [UniProtKB:Q9R0Z3]
synonym: "p19ARF (rat)" NARROW [UniProtKB:Q8QZZ9]
synonym: "p16-INK4 (rat)" NARROW [UniProtKB:Q9R0Z3]
synonym: "p16ink4a (rat)" NARROW [UniProtKB:Q9R0Z3]
synonym: "alternative reading frame (rat)" NARROW [UniProtKB:Q8QZZ9]
synonym: "cyclin-dependent kinase inhibitor 2A (rat)" NARROW [UniProtKB:Q9R0Z3]
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000029097 ! CDKN2A gene translation product
relationship: has_gene_template RGD:2323 ! Cdkn2a (rat)

[Term]
id: PR:000029097
name: CDKN2A gene translation product
def: "A protein that is a translation product of the human CDKN2A gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "MTS1" RELATED []
synonym: "CDK4I" EXACT []
synonym: "CDKN2" RELATED []
synonym: "MTS-1" EXACT []
synonym: "CDKN2A" EXACT PRO-short-label [PRO:DNx]
synonym: "p16-INK4" EXACT []
synonym: "p16INK4A" EXACT []
synonym: "p16-INK4a" EXACT []
synonym: "multiple tumor suppressor 1" EXACT []
synonym: "cyclin-dependent kinase inhibitor 2A" EXACT []
synonym: "cyclin-dependent kinase 4 inhibitor A" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:P42771-3
name: cyclin-dependent kinase inhibitor 2A isoform h3 (human)
def: "A cyclin-dependent kinase inhibitor 2A isoform 3 that is encoded in the genome of human." [PRO:DAN]
comment: Category=organism-sequence.
synonym: "hCDKN2A/iso:3" EXACT PRO-short-label [PRO:DNx]
synonym: "cyclin-dependent kinase inhibitor 2A isoform p12 (human)" EXACT [UniProtKB:P42771]
xref: UniProtKB:P42771-3
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000029145 ! cyclin-dependent kinase inhibitor 2A isoform 3