[Term]
id: PR:000047161
name: antiviral innate immune response receptor RIG-I ubiquitinated 1 (human)
def: "An antiviral innate immune response receptor RIG-I (human) that has been post-translationally modified to include ubiquitinated lysine at positions 154, 164 and 172 of the amino acid sequence represented by UniProtKB:O95786. UniProtKB:O95786, Lys-154/Lys-164/Lys-172, MOD:01148." [PRO:DNx, Reactome:R-HSA-918191]
comment: Category=organism-modification.
synonym: "hRIGI/Ubiq:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O95786, Lys-154/Lys-164/Lys-172, MOD:01148" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-918191 "PR:000047161 located_in GO:0005829"
is_a: PR:O95786 ! antiviral innate immune response receptor RIG-I (human)
relationship: has_part MOD:01148 ! ubiquitinylated lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O95786-2
name: antiviral innate immune response receptor RIG-I isoform h2 (human)
def: "An antiviral innate immune response receptor RIG-I (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O95786-2." [PRO:DNx, UniProtKB:O95786]
comment: Category=organism-sequence.
synonym: "hRIGI/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O95786-2
is_a: PR:O95786 ! antiviral innate immune response receptor RIG-I (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000029394
name: antiviral innate immune response receptor RIG-I
def: "A protein that is a translation product of the human RIGI gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "RIGI" EXACT PRO-short-label [PRO:DNx]
synonym: "DDX58" RELATED Gene-based []
synonym: "RIG-1" EXACT []
synonym: "RIG-I" EXACT []
synonym: "RLR-1" EXACT []
synonym: "RNA sensor RIG-I" EXACT []
synonym: "DEAD box protein 58" EXACT []
synonym: "RIG-I-like receptor 1" EXACT []
synonym: "ATP-dependent RNA helicase DDX58" EXACT []
synonym: "retinoic acid-inducible gene 1 protein" EXACT []
synonym: "retinoic acid-inducible gene I protein" EXACT []
synonym: "probable ATP-dependent RNA helicase DDX58" EXACT []
xref: IUPHARobj:2920
is_a: PR:000000001 ! protein

[Term]
id: PR:O95786-1
name: antiviral innate immune response receptor RIG-I isoform h1 (human)
def: "An antiviral innate immune response receptor RIG-I (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O95786-1." [PRO:DNx, UniProtKB:O95786]
comment: Category=organism-sequence.
synonym: "hRIGI/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O95786-1
is_a: PR:O95786 ! antiviral innate immune response receptor RIG-I (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O95786
name: antiviral innate immune response receptor RIG-I (human)
def: "An antiviral innate immune response receptor RIG-I that is encoded in the genome of human." [PRO:DNx, UniProtKB:O95786]
comment: Category=organism-gene.
synonym: "RIGI" RELATED Gene-based [UniProtKB:O95786]
synonym: "DDX58" RELATED Gene-based [UniProtKB:O95786]
synonym: "hRIGI" EXACT PRO-short-label [PRO:DNx]
synonym: "RIG-1 (human)" EXACT [UniProtKB:O95786]
synonym: "RIG-I (human)" EXACT [UniProtKB:O95786]
synonym: "RLR-1 (human)" EXACT [UniProtKB:O95786]
synonym: "RNA sensor RIG-I (human)" EXACT [UniProtKB:O95786]
synonym: "DEAD box protein 58 (human)" EXACT [UniProtKB:O95786]
synonym: "RIG-I-like receptor 1 (human)" EXACT [UniProtKB:O95786]
synonym: "ATP-dependent RNA helicase DDX58 (human)" EXACT [UniProtKB:O95786]
synonym: "retinoic acid-inducible gene 1 protein (human)" EXACT [UniProtKB:O95786]
synonym: "retinoic acid-inducible gene I protein (human)" EXACT [UniProtKB:O95786]
xref: Reactome:R-HSA-168917 "PR:O95786 located_in GO:0005829"
xref: UniProtKB:O95786
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000029394 ! antiviral innate immune response receptor RIG-I
relationship: has_gene_template HGNC:19102 ! RIGI (human)