[Term]
id: PR:000045036
name: histone H2B type 1-C/E/F/G/I, initiator methionine removed phosphorylated 1 (human)
def: "A histone H2B type 1-C/E/F/G/I (human) that has had the initiator methionine removed and that has been phosphorylated on the residue at the position equivalent to Ser-15 of the amino acid sequence represented by UniProtKB:P62807. UniProtKB:P62807, 2-126, Ser-15, MOD:00046." [HIstome_var_Hs:Histone_H2B_type_1-C/E/F/G/I, PMID:12757711, PRO:DAN, PRO:JPB, PRO:JR]
comment: Category=organism-modification.
synonym: "H2B_type_1-C/E/F/G/I:H2BS14ph" BROAD [HIstome_ptm_Hs:H2BS14ph]
synonym: "PRO_0000071826, Ser-15, MOD:00046" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hH2BC[4/6/7/8/10]/InitMet-/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P62807, 2-126, Ser-15, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
xref: TDR:12732
is_a: PR:P62807 ! histone H2B type 1-C/E/F/G/I (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:000045037
name: histone H2B type 1-C/E/F/G/I, initiator methionine removed acetylated 2 (human)
def: "A histone H2B type 1-C/E/F/G/I (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-21 of the amino acid sequence represented by UniProtKB:P62807. UniProtKB:P62807, 2-126, Lys-21, MOD:00064." [HIstome_var_Hs:Histone_H2B_type_1-C/E/F/G/I, PMID:16283522, PMID:18552846, PRO:DAN, PRO:JPB, PRO:JR]
comment: Category=organism-modification.
synonym: "H2B_type_1-C/E/F/G/I:H2BK20ac" BROAD [HIstome_ptm_Hs:H2BK20ac]
synonym: "hH2BC[4/6/7/8/10]/InitMet-/Ac:2" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000071826, Lys-21, MOD:00064" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P62807, 2-126, Lys-21, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-4568626 "PR:000045037 located_in GO:0005654"
is_a: PR:P62807 ! histone H2B type 1-C/E/F/G/I (human)
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:P62807
name: histone H2B type 1-C/E/F/G/I (human)
def: "A histone H2B type 1-C/E/F/G/I that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-gene. Note: The HIST1H2BC, HIST1H2BE, HIST1H2BF, HIST1H2BG, and HIST1H2BI genes encode identical proteins.
synonym: "H2BC4" RELATED Gene-based [UniProtKB:P62807]
synonym: "H2BC6" RELATED Gene-based [UniProtKB:P62807]
synonym: "H2BC7" RELATED Gene-based [UniProtKB:P62807]
synonym: "H2BC8" RELATED Gene-based [UniProtKB:P62807]
synonym: "H2BFA" RELATED Gene-based [UniProtKB:P62807]
synonym: "H2BFG" RELATED Gene-based [UniProtKB:P62807]
synonym: "H2BFH" RELATED Gene-based [UniProtKB:P62807]
synonym: "H2BFK" RELATED Gene-based [UniProtKB:P62807]
synonym: "H2BFL" RELATED Gene-based [UniProtKB:P62807]
synonym: "H2BC10" RELATED Gene-based [UniProtKB:P62807]
synonym: "HIST1H2BC" RELATED Gene-based [UniProtKB:P62807]
synonym: "HIST1H2BE" RELATED Gene-based [UniProtKB:P62807]
synonym: "HIST1H2BF" RELATED Gene-based [UniProtKB:P62807]
synonym: "HIST1H2BG" RELATED Gene-based [UniProtKB:P62807]
synonym: "HIST1H2BI" RELATED Gene-based [UniProtKB:P62807]
synonym: "H2B/a (human)" EXACT [UniProtKB:P62807]
synonym: "H2B/g (human)" EXACT [UniProtKB:P62807]
synonym: "H2B/h (human)" EXACT [UniProtKB:P62807]
synonym: "H2B/k (human)" EXACT [UniProtKB:P62807]
synonym: "H2B/l (human)" EXACT [UniProtKB:P62807]
synonym: "hH2BC[4/6/7/8/10]" EXACT PRO-short-label [PRO:DNx]
synonym: "hHIST1H2B[C/E/F/G/I]" EXACT [PRO:DAN]
synonym: "histone H2B.a (human)" EXACT [UniProtKB:P62807]
synonym: "histone H2B.g (human)" EXACT [UniProtKB:P62807]
synonym: "histone H2B.h (human)" EXACT [UniProtKB:P62807]
synonym: "histone H2B.k (human)" EXACT [UniProtKB:P62807]
synonym: "histone H2B.l (human)" EXACT [UniProtKB:P62807]
synonym: "histone H2B.1 A (human)" EXACT [UniProtKB:P62807]
xref: UniProtKB:P62807
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000029529 ! histone H2B type 1-C/E/F/G/I
relationship: has_gene_template HGNC:4746 ! HIST1H2BG (human)
relationship: has_gene_template HGNC:4752 ! HIST1H2BF (human)
relationship: has_gene_template HGNC:4753 ! HIST1H2BE (human)
relationship: has_gene_template HGNC:4756 ! HIST1H2BI (human)
relationship: has_gene_template HGNC:4757 ! HIST1H2BC (human)

[Term]
id: PR:000045035
name: histone H2B type 1-C/E/F/G/I, initiator methionine removed acetylated 1 (human)
def: "A histone H2B type 1-C/E/F/G/I (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-13 of the amino acid sequence represented by UniProtKB:P62807. UniProtKB:P62807, 2-126, Lys-13, MOD:00064." [HIstome_var_Hs:Histone_H2B_type_1-C/E/F/G/I, PMID:16283522, PMID:18552846, PMID:20693536, PRO:DAN, PRO:JPB, PRO:JR]
comment: Category=organism-modification.
synonym: "H2B_type_1-C/E/F/G/I:H2BK12ac" BROAD [HIstome_ptm_Hs:H2BK12ac]
synonym: "hH2BC[4/6/7/8/10]/InitMet-/Ac:1" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000071826, Lys-13, MOD:00064" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P62807, 2-126, Lys-13, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-4568620 "PR:000045035 located_in GO:0005654"
is_a: PR:P62807 ! histone H2B type 1-C/E/F/G/I (human)
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:000045040
name: histone H2B type 1-C/E/F/G/I, initiator methionine removed acetylated 3 (human)
def: "A histone H2B type 1-C/E/F/G/I (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-17 of the amino acid sequence represented by UniProtKB:P62807. UniProtKB:P62807, 2-126, Lys-17, MOD:00064." [HIstome_var_Hs:Histone_H2B_type_1-C/E/F/G/I, PMID:20693536, PRO:DAN, PRO:JPB, PRO:JR]
comment: Category=organism-modification.
synonym: "H2B_type_1-C/E/F/G/I:H2BK16ac" BROAD [HIstome_ptm_Hs:H2BK16ac]
synonym: "hH2BC[4/6/7/8/10]/InitMet-/Ac:3" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000071826, Lys-17, MOD:00064" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P62807, 2-126, Lys-17, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P62807 ! histone H2B type 1-C/E/F/G/I (human)
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:000045038
name: histone H2B type 1-C/E/F/G/I, initiator methionine removed ADP-ribosylated 1 (human)
def: "A histone H2B type 1-C/E/F/G/I (human) that has had the initiator methionine removed and that has been ADP-ribosylated at the position equivalent to Lys-31 of the amino acid sequence represented by UniProtKB:P62807. UniProtKB:P62807, 2-126, Lys-31, MOD:01399." [HIstome_var_Hs:Histone_H2B_type_1-C/E/F/G/I, PMID:20525793, PRO:DAN, PRO:JPB, PRO:JR]
comment: Category=organism-modification.
synonym: "H2B_type_1-C/E/F/G/I:H2BK30ar" BROAD [HIstome_ptm_Hs:H2BK30ar]
synonym: "PRO_0000071826, Lys-31, MOD:01399" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hH2BC[4/6/7/8/10]/InitMet-/ADPrib:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P62807, 2-126, Lys-31, MOD:01399" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P62807 ! histone H2B type 1-C/E/F/G/I (human)
relationship: has_part MOD:01399 ! N6-(ADP-ribosyl)-L-lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:000045039
name: histone H2B type 1-C/E/F/G/I, initiator methionine removed ubiquitinated 1 (human)
def: "A histone H2B type 1-C/E/F/G/I (human) that has had the initiator methionine removed and that has been ubiquitinated on the lysine at the position equivalent to Lys-121 of the amino acid sequence represented by UniProtKB:P62807. UniProtKB:P62807, 2-126, Lys-121, MOD:01148." [HIstome_var_Hs:Histone_H2B_type_1-C/E/F/G/I, PMID:16307923, PMID:16713563, PMID:18400894, PMID:18832071, PMID:18923072, PMID:19575011, PRO:DAN, PRO:JPB, PRO:JR]
comment: Category=organism-modification.
synonym: "H2B_type_1-C/E/F/G/I:H2BK120ub" BROAD [HIstome_ptm_Hs:H2BK120ub]
synonym: "hH2BC[4/6/7/8/10]/InitMet-/Ubiq:1" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000071826, Lys-121, MOD:01148" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P62807, 2-126, Lys-121, MOD:01148" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-3364029 "PR:000045039 located_in GO:0005654"
is_a: PR:P62807 ! histone H2B type 1-C/E/F/G/I (human)
relationship: has_part MOD:01148 ! ubiquitinylated lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:000045045
name: histone H2B type 1-C/E/F/G/I, initiator methionine removed acetylated 7 (human)
def: "A histone H2B type 1-C/E/F/G/I (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-16 of the amino acid sequence represented by UniProtKB:P62807. UniProtKB:P62807, 2-126, Lys-16, MOD:00064." [HIstome_var_Hs:Histone_H2B_type_1-C/E/F/G/I, PMID:19883641, PRO:DAN, PRO:JPB, PRO:JR]
comment: Category=organism-modification.
synonym: "H2B_type_1-C/E/F/G/I:H2BK15ac" BROAD [HIstome_ptm_Hs:H2BK15ac]
synonym: "hH2BC[4/6/7/8/10]/InitMet-/Ac:7" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000071826, Lys-16, MOD:00064" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P62807, 2-126, Lys-16, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-4568634 "PR:000045045 located_in GO:0005654"
is_a: PR:P62807 ! histone H2B type 1-C/E/F/G/I (human)
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:000045044
name: histone H2B type 1-C/E/F/G/I, initiator methionine removed acetylated 6 (human)
def: "A histone H2B type 1-C/E/F/G/I (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-121 of the amino acid sequence represented by UniProtKB:P62807. UniProtKB:P62807, 2-126, Lys-121, MOD:00064." [HIstome_var_Hs:Histone_H2B_type_1-C/E/F/G/I, PMID:18552846, PRO:DAN, PRO:JPB, PRO:JR]
comment: Category=organism-modification.
synonym: "H2B_type_1-C/E/F/G/I:H2BK120ac" BROAD [HIstome_ptm_Hs:H2BK120ac]
synonym: "hH2BC[4/6/7/8/10]/InitMet-/Ac:6" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000071826, Lys-121, MOD:00064" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P62807, 2-126, Lys-121, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P62807 ! histone H2B type 1-C/E/F/G/I (human)
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:000045043
name: histone H2B type 1-C/E/F/G/I, initiator methionine removed acetylated 5 (human)
def: "A histone H2B type 1-C/E/F/G/I (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-47 of the amino acid sequence represented by UniProtKB:P62807. UniProtKB:P62807, 2-126, Lys-47, MOD:00064." [HIstome_var_Hs:Histone_H2B_type_1-C/E/F/G/I, PMID:20693536, PRO:DAN, PRO:JPB, PRO:JR]
comment: Category=organism-modification.
synonym: "H2B_type_1-C/E/F/G/I:H2BK46ac" BROAD [HIstome_ptm_Hs:H2BK46ac]
synonym: "hH2BC[4/6/7/8/10]/InitMet-/Ac:5" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000071826, Lys-47, MOD:00064" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P62807, 2-126, Lys-47, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P62807 ! histone H2B type 1-C/E/F/G/I (human)
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:000045042
name: histone H2B type 1-C/E/F/G/I, initiator methionine removed monomethylated 1 (human)
def: "A histone H2B type 1-C/E/F/G/I (human) that has had the initiator methionine removed and that has been monomethylated at the position equivalent to Lys-6 of the amino acid sequence represented by UniProtKB:P62807. UniProtKB:P62807, 2-126, Lys-6, MOD:00085." [HIstome_var_Hs:Histone_H2B_type_1-C/E/F/G/I, PMID:17512414, PRO:DAN, PRO:JPB, PRO:JR]
comment: Category=organism-modification.
synonym: "H2B_type_1-C/E/F/G/I:H2BK5me1" BROAD [HIstome_ptm_Hs:H2BK5me1]
synonym: "PRO_0000071826, Lys-6, MOD:00085" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hH2BC[4/6/7/8/10]/InitMet-/Me1:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P62807, 2-126, Lys-6, MOD:00085" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P62807 ! histone H2B type 1-C/E/F/G/I (human)
relationship: has_part MOD:00085 ! N6-methyl-L-lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:000045041
name: histone H2B type 1-C/E/F/G/I, initiator methionine removed acetylated 4 (human)
def: "A histone H2B type 1-C/E/F/G/I (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-6 of the amino acid sequence represented by UniProtKB:P62807. UniProtKB:P62807, 2-126, Lys-6, MOD:00064." [HIstome_var_Hs:Histone_H2B_type_1-C/E/F/G/I, PMID:18552846, PRO:DAN, PRO:JPB, PRO:JR]
comment: Category=organism-modification.
synonym: "H2B_type_1-C/E/F/G/I:H2BK5ac" BROAD [HIstome_ptm_Hs:H2BK5ac]
synonym: "hH2BC[4/6/7/8/10]/InitMet-/Ac:4" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000071826, Lys-6, MOD:00064" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P62807, 2-126, Lys-6, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-4568623 "PR:000045041 located_in GO:0005654"
is_a: PR:P62807 ! histone H2B type 1-C/E/F/G/I (human)
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:000036257
name: histone H2B type 1-C/E/F/G/I acetylated 1 (human)
def: "A histone H2B type 1-C/E/F/G/I that is N-terminal Met acetylated in human. UniProtKB:P62807, Met-1, MOD:00058." [TDR:2043]
comment: Category=organism-modification. Note: Top down proteomics. Evidence=(ECO:0000006).
synonym: "hH2BC[4/6/7/8/10]/Ac:1" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P62807, Met-1, MOD:00058" EXACT PRO-proteoform-std [PRO:DNx]
xref: TDR:2043
is_a: PR:000029529 ! histone H2B type 1-C/E/F/G/I
relationship: has_part MOD:00058 ! N-acetyl-L-methionine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000029529
name: histone H2B type 1-C/E/F/G/I
def: "A histone H2B that is a translation product of the human HIST1H2BC, HIST1H2BE, HIST1H2BF, HIST1H2BG, or HIST1H2BI genes, 1:1 orthologs thereof, or a semi-ortholog thereof." [PRO:DAN]
comment: Category=gene. Note: The human HIST1H2BC, HIST1H2BE, HIST1H2BF, HIST1H2BG, and HIST1H2BI genes encode identical proteins.
synonym: "H2B/a" NARROW [PRO:DAN]
synonym: "H2B/g" NARROW [PRO:DAN]
synonym: "H2B/h" NARROW [PRO:DAN]
synonym: "H2B/k" NARROW [PRO:DAN]
synonym: "H2B/l" NARROW [PRO:DAN]
synonym: "H2BC4" NARROW Gene-based [PRO:DAN]
synonym: "H2BC6" NARROW Gene-based [PRO:DAN]
synonym: "H2BC7" NARROW Gene-based [PRO:DAN]
synonym: "H2BC8" NARROW Gene-based [PRO:DAN]
synonym: "H2BFA" NARROW Gene-based [PRO:DAN]
synonym: "H2BFG" NARROW Gene-based [PRO:DAN]
synonym: "H2BFH" NARROW Gene-based [PRO:DAN]
synonym: "H2BFK" RELATED Gene-based []
synonym: "H2BFL" NARROW Gene-based [PRO:DAN]
synonym: "H2BC10" NARROW Gene-based [PRO:DAN]
synonym: "HIST1H2BC" NARROW Gene-based [PRO:DAN]
synonym: "HIST1H2BE" NARROW Gene-based [PRO:DAN]
synonym: "HIST1H2BF" NARROW Gene-based [PRO:DAN]
synonym: "HIST1H2BG" NARROW Gene-based [PRO:DAN]
synonym: "HIST1H2BI" NARROW Gene-based [PRO:DAN]
synonym: "histone H2B.a" NARROW [PRO:DAN]
synonym: "histone H2B.g" NARROW [PRO:DAN]
synonym: "histone H2B.h" NARROW [PRO:DAN]
synonym: "histone H2B.k" NARROW [PRO:DAN]
synonym: "histone H2B.l" NARROW [PRO:DAN]
synonym: "histone H2B.1 A" NARROW [PRO:DAN]
synonym: "H2BC[4/6/7/8/10]" EXACT PRO-short-label [PRO:DNx]
synonym: "HIST1H2B[C/E/F/G/I]" EXACT [PRO:DNx]
is_a: PR:000036509 ! histone H2B