[Term] id: PR:000047815 name: histone H2B type 1-N, initiator methionine removed N6-acetyllysine form (human) def: "A histone H2B type 1-N (human) that has had the initiator methionine removed and that includes at least one N6-acetyllysine. UniProtKB:Q99877, 2-126, MOD:00064." [PRO:DNx, Reactome:R-HSA-4549274] comment: Category=organism-modification. synonym: "PRO_0000071830, MOD:00064" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hHIST1H2BN/InitMet-/N6AcLys+" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q99877, 2-126, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-4549274 "PR:000047815 located_in GO:0005654" intersection_of: has_part MOD:00064 ! N6-acetyl-L-lysine intersection_of: lacks_part PR:000021937 ! initiator methionine intersection_of: PR:Q99877 ! histone H2B type 1-N (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000045119 name: histone H2B type 1-N, initiator methionine removed monomethylated 1 (human) def: "A histone H2B type 1-N (human) that has had the initiator methionine removed and that has been monomethylated at the position equivalent to Lys-6 of the amino acid sequence represented by UniProtKB:Q99877. UniProtKB:Q99877, 2-126, Lys-6, MOD:00085." [HIstome_var_Hs:Histone_H2B_type_1-N, PMID:17512414, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H2B_type_1-N:H2BK5me1" BROAD [HIstome_ptm_Hs:H2BK5me1] synonym: "hHIST1H2BN/InitMet-/Me1:1" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000071830, Lys-6, MOD:00085" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q99877, 2-126, Lys-6, MOD:00085" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q99877 ! histone H2B type 1-N (human) relationship: has_part MOD:00085 ! N6-methyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045118 name: histone H2B type 1-N, initiator methionine removed acetylated 4 (human) def: "A histone H2B type 1-N (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-6 of the amino acid sequence represented by UniProtKB:Q99877. UniProtKB:Q99877, 2-126, Lys-6, MOD:00064." [HIstome_var_Hs:Histone_H2B_type_1-N, PMID:18552846, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H2B_type_1-N:H2BK5ac" BROAD [HIstome_ptm_Hs:H2BK5ac] synonym: "hHIST1H2BN/InitMet-/Ac:4" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000071830, Lys-6, MOD:00064" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q99877, 2-126, Lys-6, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-4568721 "PR:000045118 located_in GO:0005654" xref: TDR:12947 is_a: PR:Q99877 ! histone H2B type 1-N (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000036261 name: histone H2B type 1-N acetylated 1 (human) def: "A histone H2B type 1-N that is N-terminal Met acetylated in human. UniProtKB:Q99877, Met-1, MOD:00058." [TDR:1919] comment: Category=organism-modification. Note: Top down proteomics. Evidence=(ECO:0000006). synonym: "hHIST1H2BN/Ac:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q99877, Met-1, MOD:00058" EXACT PRO-proteoform-std [PRO:DNx] xref: TDR:1919 is_a: PR:000029531 ! histone H2B type 1-N relationship: has_part MOD:00058 ! N-acetyl-L-methionine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000045114 name: histone H2B type 1-N, initiator methionine removed acetylated 2 (human) def: "A histone H2B type 1-N (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-21 of the amino acid sequence represented by UniProtKB:Q99877. UniProtKB:Q99877, 2-126, Lys-21, MOD:00064." [HIstome_var_Hs:Histone_H2B_type_1-N, PMID:16283522, PMID:18552846, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H2B_type_1-N:H2BK20ac" BROAD [HIstome_ptm_Hs:H2BK20ac] synonym: "hHIST1H2BN/InitMet-/Ac:2" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000071830, Lys-21, MOD:00064" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q99877, 2-126, Lys-21, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-4568689 "PR:000045114 located_in GO:0005654" is_a: PR:Q99877 ! histone H2B type 1-N (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045117 name: histone H2B type 1-N, initiator methionine removed acetylated 3 (human) def: "A histone H2B type 1-N (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-17 of the amino acid sequence represented by UniProtKB:Q99877. UniProtKB:Q99877, 2-126, Lys-17, MOD:00064." [HIstome_var_Hs:Histone_H2B_type_1-N, PMID:20693536, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H2B_type_1-N:H2BK16ac" BROAD [HIstome_ptm_Hs:H2BK16ac] synonym: "hHIST1H2BN/InitMet-/Ac:3" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000071830, Lys-17, MOD:00064" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q99877, 2-126, Lys-17, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q99877 ! histone H2B type 1-N (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045116 name: histone H2B type 1-N, initiator methionine removed ubiquitinated 1 (human) def: "A histone H2B type 1-N (human) that has had the initiator methionine removed and that has been ubiquitinated on the lysine at the position equivalent to Lys-121 of the amino acid sequence represented by UniProtKB:Q99877. UniProtKB:Q99877, 2-126, Lys-121, MOD:01148." [HIstome_var_Hs:Histone_H2B_type_1-N, PMID:16307923, PMID:16713563, PMID:18400894, PMID:18832071, PMID:18923072, PMID:19575011, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. Note: A correction of the sequence numbering of the source data (Reactome:R-HSA-6782569) rendered PR:000047816 identical to this entry. synonym: "H2B_type_1-N:H2BK120ub" BROAD [HIstome_ptm_Hs:H2BK120ub] synonym: "hHIST1H2BN/InitMet-/Ubiq:1" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000071830, Lys-121, MOD:01148" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q99877, 2-126, Lys-121, MOD:01148" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-3364012 "PR:000045116 located_in GO:0005654" is_a: PR:Q99877 ! histone H2B type 1-N (human) relationship: has_part MOD:01148 ! ubiquitinylated lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045113 name: histone H2B type 1-N, initiator methionine removed phosphorylated 1 (human) def: "A histone H2B type 1-N (human) that has had the initiator methionine removed and that has been phosphorylated on the residue at the position equivalent to Ser-15 of the amino acid sequence represented by UniProtKB:Q99877. UniProtKB:Q99877, 2-126, Ser-15, MOD:00046." [HIstome_var_Hs:Histone_H2B_type_1-N, PMID:12757711, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H2B_type_1-N:H2BS14ph" BROAD [HIstome_ptm_Hs:H2BS14ph] synonym: "hHIST1H2BN/InitMet-/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000071830, Ser-15, MOD:00046" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q99877, 2-126, Ser-15, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx] xref: TDR:1664 is_a: PR:Q99877 ! histone H2B type 1-N (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045112 name: histone H2B type 1-N, initiator methionine removed acetylated 1 (human) def: "A histone H2B type 1-N (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-13 of the amino acid sequence represented by UniProtKB:Q99877. UniProtKB:Q99877, 2-126, Lys-13, MOD:00064." [HIstome_var_Hs:Histone_H2B_type_1-N, PMID:16283522, PMID:18552846, PMID:20693536, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H2B_type_1-N:H2BK12ac" BROAD [HIstome_ptm_Hs:H2BK12ac] synonym: "hHIST1H2BN/InitMet-/Ac:1" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000071830, Lys-13, MOD:00064" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q99877, 2-126, Lys-13, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-4568653 "PR:000045112 located_in GO:0005654" is_a: PR:Q99877 ! histone H2B type 1-N (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000029531 name: histone H2B type 1-N def: "A histone H2B that is a translation product of the human H2BC15 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "H2B/d" EXACT [] synonym: "H2BFD" RELATED Gene-based [] synonym: "H2BC15" EXACT PRO-short-label [PRO:DNx] synonym: "HIST1H2BN" RELATED Gene-based [] synonym: "histone H2B.d" EXACT [] is_a: PR:000036509 ! histone H2B [Term] id: PR:000045115 name: histone H2B type 1-N, initiator methionine removed ADP-ribosylated 1 (human) def: "A histone H2B type 1-N (human) that has had the initiator methionine removed and that has been ADP-ribosylated at the position equivalent to Lys-31 of the amino acid sequence represented by UniProtKB:Q99877. UniProtKB:Q99877, 2-126, Lys-31, MOD:01399." [HIstome_var_Hs:Histone_H2B_type_1-N, PMID:20525793, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H2B_type_1-N:H2BK30ar" BROAD [HIstome_ptm_Hs:H2BK30ar] synonym: "hHIST1H2BN/InitMet-/ADPrib:1" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000071830, Lys-31, MOD:01399" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q99877, 2-126, Lys-31, MOD:01399" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q99877 ! histone H2B type 1-N (human) relationship: has_part MOD:01399 ! N6-(ADP-ribosyl)-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045120 name: histone H2B type 1-N, initiator methionine removed acetylated 5 (human) def: "A histone H2B type 1-N (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-47 of the amino acid sequence represented by UniProtKB:Q99877. UniProtKB:Q99877, 2-126, Lys-47, MOD:00064." [HIstome_var_Hs:Histone_H2B_type_1-N, PMID:20693536, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H2B_type_1-N:H2BK46ac" BROAD [HIstome_ptm_Hs:H2BK46ac] synonym: "hHIST1H2BN/InitMet-/Ac:5" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000071830, Lys-47, MOD:00064" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q99877, 2-126, Lys-47, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q99877 ! histone H2B type 1-N (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045121 name: histone H2B type 1-N, initiator methionine removed acetylated 6 (human) def: "A histone H2B type 1-N (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-121 of the amino acid sequence represented by UniProtKB:Q99877. UniProtKB:Q99877, 2-126, Lys-121, MOD:00064." [HIstome_var_Hs:Histone_H2B_type_1-N, PMID:18552846, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H2B_type_1-N:H2BK120ac" BROAD [HIstome_ptm_Hs:H2BK120ac] synonym: "hHIST1H2BN/InitMet-/Ac:6" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000071830, Lys-121, MOD:00064" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q99877, 2-126, Lys-121, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q99877 ! histone H2B type 1-N (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045122 name: histone H2B type 1-N, initiator methionine removed acetylated 7 (human) def: "A histone H2B type 1-N (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-16 of the amino acid sequence represented by UniProtKB:Q99877. UniProtKB:Q99877, 2-126, Lys-16, MOD:00064." [HIstome_var_Hs:Histone_H2B_type_1-N, PMID:19883641, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H2B_type_1-N:H2BK15ac" BROAD [HIstome_ptm_Hs:H2BK15ac] synonym: "hHIST1H2BN/InitMet-/Ac:7" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000071830, Lys-16, MOD:00064" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q99877, 2-126, Lys-16, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-4568693 "PR:000045122 located_in GO:0005654" is_a: PR:Q99877 ! histone H2B type 1-N (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000047810 name: histone H2B type 1-N, initiator methionine removed form (human) def: "A histone H2B type 1-N (human) that has had the initiator methionine removed. UniProtKB:Q99877, 2-126." [PRO:DNx, Reactome:R-HSA-181907, Reactome:R-HSA-977559] comment: Category=organism-modification. synonym: "PRO_0000071830" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hHIST1H2BN/InitMet-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q99877, 2-126" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-181907 "PR:000047810 located_in GO:0005654" xref: Reactome:R-HSA-977559 "PR:000047810 located_in GO:0005576" xref: TDR:1887 intersection_of: lacks_part PR:000021937 ! initiator methionine intersection_of: PR:Q99877 ! histone H2B type 1-N (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q99877 name: histone H2B type 1-N (human) def: "A histone H2B type 1-N that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q99877] comment: Category=organism-gene. synonym: "H2BFD" RELATED Gene-based [UniProtKB:Q99877] synonym: "H2BC15" RELATED Gene-based [UniProtKB:Q99877] synonym: "hH2BC15" EXACT PRO-short-label [PRO:DNx] synonym: "HIST1H2BN" RELATED Gene-based [UniProtKB:Q99877] synonym: "H2B/d (human)" EXACT [UniProtKB:Q99877] synonym: "histone H2B.d (human)" EXACT [UniProtKB:Q99877] xref: UniProtKB:Q99877 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000029531 ! histone H2B type 1-N relationship: has_gene_template HGNC:4749 ! H2BC15 (human)