[Term] id: PR:Q8N884 name: cyclic GMP-AMP synthase (human) def: "A protein MB21D1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q8N884] comment: Category=organism-gene. synonym: "CGAS" RELATED Gene-based [UniProtKB:Q8N884] synonym: "hCGAS" EXACT PRO-short-label [PRO:DNx] synonym: "MB21D1" RELATED Gene-based [UniProtKB:Q8N884] synonym: "h-cGAS" EXACT [UniProtKB:Q8N884] synonym: "C6orf150" RELATED Gene-based [UniProtKB:Q8N884] synonym: "cGAS (human)" EXACT [UniProtKB:Q8N884] synonym: "cGAMP synthase (human)" EXACT [UniProtKB:Q8N884] synonym: "2'3'-cGAMP synthase (human)" EXACT [UniProtKB:Q8N884] synonym: "Mab-21 domain-containing protein 1 (human)" EXACT [UniProtKB:Q8N884] xref: Reactome:R-HSA-3244653 "PR:Q8N884 located_in GO:0005829" xref: UniProtKB:Q8N884 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000030833 ! protein MB21D1 relationship: has_gene_template HGNC:21367 ! CGAS (human) [Term] id: PR:Q8N884-1 name: cyclic GMP-AMP synthase isoform h1 (human) def: "A cyclic GMP-AMP synthase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8N884-1." [PRO:DNx, UniProtKB:Q8N884] comment: Category=organism-sequence. synonym: "hCGAS/iso:h1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q8N884-1 is_a: PR:Q8N884 ! cyclic GMP-AMP synthase (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q8C6L5 name: cyclic GMP-AMP synthase (mouse) def: "A protein MB21D1 that is encoded in the genome of mouse." [OMA:Q8C6L5, PRO:DNx] comment: Category=organism-gene. synonym: "Cgas" RELATED Gene-based [UniProtKB:Q8C6L5] synonym: "mCGAS" EXACT PRO-short-label [PRO:DNx] synonym: "Mb21d1" RELATED Gene-based [UniProtKB:Q8C6L5] synonym: "m-cGAS" EXACT [UniProtKB:Q8C6L5] synonym: "cGAS (mouse)" EXACT [UniProtKB:Q8C6L5] synonym: "cGAMP synthase (mouse)" EXACT [UniProtKB:Q8C6L5] synonym: "2'3'-cGAMP synthase (mouse)" EXACT [UniProtKB:Q8C6L5] synonym: "Mab-21 domain-containing protein 1 (mouse)" EXACT [UniProtKB:Q8C6L5] xref: UniProtKB:Q8C6L5 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000030833 ! protein MB21D1 relationship: has_gene_template MGI:2442261 ! Cgas (mouse) [Term] id: PR:000030833 name: protein MB21D1 def: "A protein that is a translation product of the human CGAS gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "CGAS" EXACT PRO-short-label [PRO:DNx] synonym: "MB21D1" RELATED Gene-based [] synonym: "C6orf150" RELATED Gene-based [] synonym: "cGAMP synthase" EXACT [] synonym: "2'3'-cGAMP synthase" EXACT [] synonym: "Mab-21 domain-containing protein 1" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:Q8N884-2 name: cyclic GMP-AMP synthase isoform h2 (human) def: "A cyclic GMP-AMP synthase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8N884-2." [PRO:DNx, UniProtKB:Q8N884] comment: Category=organism-sequence. synonym: "hCGAS/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q8N884-2 is_a: PR:Q8N884 ! cyclic GMP-AMP synthase (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens