[Term]
id: PR:D4A5C3-1
name: 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic isoform 1 (rat)
def: "A 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rHMGCLL1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:D4A5C3-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000041769 ! 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic isoform 1

[Term]
id: PR:000032551
name: 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic
def: "A protein that is a translation product of the human HMGCLL1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "er-cHL" EXACT []
synonym: "HMGCLL1" EXACT PRO-short-label [PRO:DNx]
synonym: "3-hydroxy-3-methylglutaryl-CoA lyase-like protein 1" EXACT []
synonym: "3-hydroxymethyl-3-methylglutaryl-CoA lyase-like protein 1" EXACT []
synonym: "endoplasmic reticulum 3-hydroxymethyl-3-methylglutaryl-CoA lyase" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q8TB92-4
name: 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic isoform h3 (human)
def: "A 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8TB92-4." [PRO:DNx, UniProtKB:Q8TB92]
comment: Category=organism-sequence.
synonym: "hHMGCLL1/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8TB92-4
is_a: PR:Q8TB92 ! 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:D4A5C3
name: 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic (rat)
def: "A 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic that is encoded in the genome of rat." [OMA:D4A5C3, PRO:DNx]
comment: Category=organism-gene.
synonym: "Hmgcll1" RELATED Gene-based [UniProtKB:D4A5C3]
synonym: "rHMGCLL1" EXACT PRO-short-label [PRO:DNx]
synonym: "3-hydroxy-3-methylglutaryl-CoA lyase-like protein 1 (rat)" EXACT [UniProtKB:D4A5C3]
xref: UniProtKB:D4A5C3
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000032551 ! 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic
relationship: has_gene_template RGD:1565090 ! Hmgcll1 (rat)

[Term]
id: PR:Q8TB92-1
name: 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic isoform h1 (human)
def: "A 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8TB92-1." [PRO:DNx, UniProtKB:Q8TB92]
comment: Category=organism-sequence.
synonym: "hHMGCLL1/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8TB92-1
is_a: PR:Q8TB92 ! 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q8JZS7
name: 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic (mouse)
def: "A 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic that is encoded in the genome of mouse." [OMA:Q8JZS7, PRO:DNx]
comment: Category=organism-gene.
synonym: "Hmgcll1" RELATED Gene-based [UniProtKB:Q8JZS7]
synonym: "mHMGCLL1" EXACT PRO-short-label [PRO:DNx]
synonym: "3-hydroxy-3-methylglutaryl-CoA lyase-like protein 1 (mouse)" EXACT [UniProtKB:Q8JZS7]
xref: UniProtKB:Q8JZS7
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000032551 ! 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic
relationship: has_gene_template MGI:2446108 ! Hmgcll1 (mouse)

[Term]
id: PR:Q8JZS7-1
name: 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic isoform 1 (mouse)
def: "A 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mHMGCLL1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8JZS7-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000041769 ! 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic isoform 1

[Term]
id: PR:Q8TB92-2
name: 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic isoform h2 (human)
def: "A 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8TB92-2." [PRO:DNx, UniProtKB:Q8TB92]
comment: Category=organism-sequence.
synonym: "hHMGCLL1/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8TB92-2
is_a: PR:Q8TB92 ! 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000047880
name: 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic, initiator methionine removed form (human)
def: "A 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic (human) that has had the initiator methionine removed. UniProtKB:Q8TB92, 2-370." [PRO:DNx, Reactome:R-HSA-6788599]
comment: Category=organism-modification.
synonym: "PRO_0000334669" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hHMGCLL1/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q8TB92, 2-370" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-6788599 "PR:000047880 located_in GO:0005829"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:Q8TB92 ! 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q8TB92-5
name: 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic isoform h4 (human)
def: "A 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8TB92-5." [PRO:DNx, UniProtKB:Q8TB92]
comment: Category=organism-sequence.
synonym: "hHMGCLL1/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8TB92-5
is_a: PR:Q8TB92 ! 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000041769
name: 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic isoform 1
def: "A 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8JZS7-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "HMGCLL1/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000032551 ! 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic

[Term]
id: PR:A8WG57
name: 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic (zebrafish)
def: "A 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic that is encoded in the genome of zebrafish." [PRO:DNx]
comment: Category=organism-gene.
synonym: "hmgcll1" RELATED Gene-based [UniProtKB:A8WG57]
synonym: "z-HMGCLL1" EXACT PRO-short-label [PRO:DNx]
synonym: "zgc:172206" RELATED Gene-based [UniProtKB:A8WG57]
synonym: "3-hydroxy-3-methylglutaryl-CoA lyase-like protein 1 (zebrafish)" EXACT [UniProtKB:A8WG57]
xref: UniProtKB:A8WG57
intersection_of: only_in_taxon NCBITaxon:7955 ! Danio rerio
intersection_of: PR:000032551 ! 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic
relationship: has_gene_template ZFIN:ZDB-GENE-080220-15 ! hmgcll1 (zebrafish)

[Term]
id: PR:Q8TB92
name: 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic (human)
def: "A 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q8TB92]
comment: Category=organism-gene.
synonym: "HMGCLL1" RELATED Gene-based [UniProtKB:Q8TB92]
synonym: "hHMGCLL1" EXACT PRO-short-label [PRO:DNx]
synonym: "er-cHL (human)" EXACT [UniProtKB:Q8TB92]
synonym: "HMGCL-like 1 (human)" EXACT [UniProtKB:Q8TB92]
synonym: "3-hydroxy-3-methylglutaryl-CoA lyase-like protein 1 (human)" EXACT [UniProtKB:Q8TB92]
synonym: "endoplasmic reticulum 3-hydroxy-3-methylglutaryl-CoA lyase (human)" EXACT [UniProtKB:Q8TB92]
xref: UniProtKB:Q8TB92
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000032551 ! 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic
relationship: has_gene_template HGNC:21359 ! HMGCLL1 (human)