[Term]
id: PR:000036800
name: histone H3.3 acetylated and methylated 1 (human)
def: "A histone H3.3 that has been acetylated on the N-terminal Met and methylated and acetylated on several Lys residues in human. UniProtKB:P84243, Met-1, MOD:00058|Lys-10, MOD:00083|Lys-28, MOD:00084|Lys-80, MOD:00064." [TDR:7224]
comment: Category=organism-modification. Note: Top down proteomics. Evidence=(ECO:0000006).
synonym: "hH3.3/AcMe:1" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P84243, Met-1, MOD:00058|Lys-10, MOD:00083|Lys-28, MOD:00084|Lys-80, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx]
xref: TDR:7224
is_a: PR:000008425 ! histone H3.3
relationship: has_part MOD:00058 ! N-acetyl-L-methionine
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine
relationship: has_part MOD:00083 ! N6,N6,N6-trimethyl-L-lysine
relationship: has_part MOD:00084 ! N6,N6-dimethyl-L-lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens