[Term]
id: PR:000045295
name: histone H3.3, initiator methionine removed dimethylated 4 (human)
def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been dimethylated at the position equivalent to Lys-80 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Lys-80, MOD:00084." [HIstome_var_Hs:Histone_H3.3, PMID:12123582, PMID:16307923, PMID:20699226, PMID:21741597, PRO:DAN, PRO:JPB, PRO:JR]
comment: Category=organism-modification.
synonym: "H3.3:H3K79me2" BROAD [HIstome_ptm_Hs:H3K79me2]
synonym: "hH3.3/InitMet-/Me2:4" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P84243, 2-136, Lys-80, MOD:00084" EXACT PRO-proteoform-std [PRO:DNx]
xref: TDR:12831
is_a: PR:P84243 ! histone H3.3 (human)
relationship: has_part MOD:00084 ! N6,N6-dimethyl-L-lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part PR:000021937 ! initiator methionine